Báo cáo y học: " Review of "Witches, Westerners, and HIV: AIDS and Cultures of Blame in Africa" by Alexander Rodlac" pdf

... 1 of 2(page number not for citation purposes) AIDS Research and TherapyOpen AccessBook review Review of "Witches, Westerners, and HIV: AIDS and Cultures of Blame in Africa" by Alexander ... explana-tory models of the AIDS epidemic and offers a convincing and fine-grained analysis of the African quest to explain and account for personal misfortune in a time of signifi-cant social and economic ... success of AIDS intervention programs in Africa. Second is the chal-lenge of explaining the culturally coherent logic behindthe seemingly irrational and contradictory views of Afri-cans who blame...

Báo cáo y học: " Review of the use of Topiramate for treatment of psychiatric disorders" pptx

... per drinking day, percentage of heavy drinking day, percentage of day abstinent) and plasma gamma-glutamyl transferase as an objective index of alcohol consumption. The secondary efficacy variablewas ... encour-aging considering the rather disappointing success rates of efficacious prevention programs [110] and have potentialimplications in reversing increased body weight and obes-ity induced by psychotropic ... CGI rating scales were used. Atstudy entry, patients had a minimum score of 12 on YMRS and HAM-D and a minimum score of 4 on CGI. Topiram-ate was introduced at the dose of 25 mg/day and increasedby...

Báo cáo y học: " Review Cells of the synovium in rheumatoid arthritis" ppsx

... interferon-γ producing cells, which areknown to be involved in the induction and maintenance of theproinflammatory cytokine cascade.Role played by B cells as antigen-presentingcells in rheumatoid ... bindingprotein, both of which are found in early RA and pre-diseasesera [29]. Antibody and T-cell reponses to heavy chain bindingprotein have been identified both in patients with RA and in animal ... approachthan targeting a single cytokine or chemokine.The role played by B cells in the maintenance of ectopicgerminal centre-like structures, as well as in the immuneresponse in RA synovium, has...

Báo cáo y học: " Review Cells of the synovium in rheumatoid arthritis" pot

... antigen-presenting and antigen-priming cells of the immune system. We review the antigen-presenting and proinflammatory roles played by dendritic cells in the initiation of rheumatoid arthritis (RA) and ... proteins such as vimentin may be acquired by ingestion of apoptotic macrophages. Effector function,including cytokine production and B-cell and monocytehelp, of autoantigen-specific memory T ... proinflammatory cytokines [36-38]. NF-κB-induced cytokines such as TNF, IL-1 and IL-6 activate innateresponses in RA, leading to the release of C-reactive protein(CRP) and complement, and...

Báo cáo y học: "Review Cells of the synovium in rheumatoid arthritis" pot

... cytokines are produced in the inflamed synovium as a result of the influx of inflammatory cells from the circulation and synovial cell hyperplasia. The upregulation of proinflammatory cytokines ... highexpression of the inhibitor of Wnt/β-catenin signaling, DKK-1, in the inflamed synovium, especially in the synoviocytes and synovial microvessels, and in cartilage adjacent to inflam-matory tissue ... cellularinteractions in the RA joint involving macrophages, T and Blymphocytes, and synovial fibroblasts. Laboratory investi-gations in vitro and in vivo have resulted in new findingsabout the role of the...

Báo cáo y học: "Review Cells of the synovium in rheumatoid arthritis" ppsx

... antigenpresentation in monocytes and inhibits the production of pro-inflammatory cytokines, GM-CSF, and Fc-γ receptors by synovial Mφ. Consistently with cytokine and chemokinedownregulation, IL-10 clearly suppresses ... post-injury tissue remodelling (reviewed in [2])Lipid metabolism Mφ synthesis of prostaglandins (PGs) E2 and I2Pro-inflammatory activity of PGE2 and PGI2 and leukotrienes in Expression of ... molecules and TGF-β receptors in the lining and sublining layers, at the cartilage-pannus junction, and in thesynovial fluid [78-80]. The pro-inflammatory effects of TGF-βare substantiated by induction...

Báo cáo y học: "Review of "The Twelfth West Coast Retrovirus Meeting" and "The Twenty-third Annual Symposium on Nonhuman Primate Models for AIDS"" doc

... results in a frame work, a model was proposed in which the drug inhibits the final Gag cleavage step by binding to a pocket formed by oligomerization of Gagduring particle assembly, thereby blocking ... immunityIt is becoming increasingly evident that the innateimmune system plays a critical role in the control of infec-tious diseases. Harvesting the potential of this system in the treatment and ... experienced in supplying treatments in manyparts of the world make it imperative that additional waysto stop the infection, including effective vaccines and AIDS Research and Therapy 2006, 3:1...

Báo cáo y học: " Review of "HIV Chemotherapy: a Critical Review" by Salvatore T. Butera" docx

... of its class to enter clinicaltrials. The chapter on RNAi is a nice summary of the state of the art in this rapidly emerging field. As was pointedout by the authors, given the specificity of ... Central yours — you keep the copyrightSubmit your manuscript here:http://www.biomedcentral.com/info/publishing_adv.aspBioMedcentral AIDS Research and Therapy 2006, 3:7 http://www.aidsrestherapy.com/content/3/1/7Page ... molecules and the inherent difficulties in delivering them to the cells of interest, it is unclear whether this strategy will have animpact as a therapy on a virus as heterogeneous and rap-idly changing...

Báo cáo y học: " Review of Anton A. Niekerk and Loretta M. Kopelman (eds.) Ethics and AIDS in Africa: The Challenge to our Thinking" pptx

... since theBlack Plague of the 14th century. And Africa: cradle of humankind, burdened by colonization, famine, poverty and civil war. In what ways do ethics, AIDS and Africa gotogether, and ... impact of AIDS in sub-Saharan Africa and take on some of the key ethicalissues raised by HIV /AIDS research, policy and clinicalpractice in the region. Although rich in details, it is fair tosay ... suffering from AIDS in thedeveloping world, but given the money-making impera-tives of big pharma, this responsibility can only realisti-cally take the form of some investment in R&D in thedeveloping...

Báo cáo y học: " Tropheryma whipplei tricuspid endocarditis: a case report and review of the literature" ppsx

... association of a lysotropic agent(hydroxychloroquine) to doxycycline tends to reduce theacidity of the vacuole in which Tropheryma whipplei islocated and thus improves the efficacy of doxycyclineinactive ... clear.Concerning treatment, our patient was initially treated by ceftriaxone then with a combination of sulfamethoxa-zole/trimethoprim, hydroxychloroquine and doxycyclinefor one year. By analogy with ... dayfor a minimum of one year. The blood levels of doxycy-cline and hydroxychloroquine were measured every othermont h and doses adapted to therapeutic levels (doxycy-cline: > 5 μg/ml, hydroxychloroquine...

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