Báo cáo y học: "Glutathione and growth inhibition of Mycobac

Báo cáo y học: "Glutathione and growth inhibition of Mycobacterium tuberculosis in healthy and HIV infected subjects" pot

... 3c). Assay of cytokines in blood culture supernatants from healthy and HIV- positive subjects Cytokines were measured in blood culture supernatants from healthy and HIV- infected subjects. Interestingly, ... synthesis in response to H37Rv infection and NAC treatment was similar in healthy subjects and HIV patients. H37Rv induced almost ten-fold increases in IL-...

Ngày tải lên : 10/08/2014, 05:20

12
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Báo cáo y học: "RANKL increases the level of Mcl-1 in osteoclasts and reduces bisphosphonate-induced osteoclast apoptosis in vitro" pps

... retraction and alterations in plasma membrane morphology) are consistent with the inhibition of FPP synthase. This leads to the inhibition of protein prenylation and the slow accumulation of unpre- nylated ... generally been disappointing. We examined whether the ability of bisphosphonates to induce osteoclast apoptosis and inhibit bone resorption in vitro is influenced...

Ngày tải lên : 09/08/2014, 14:20

9
497
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Báo cáo y học: "Fat-Storing Multilocular Cells Expressing CCR5 Increase in the Thymus with Advancing Age: Potential Role for CCR5 Ligands on the Differentiation and Migration of Preadipocytes" pot

... novel con- ceptual point of view concerning the understanding of the process of thymic physiology in aging, where the increase in adipocytes an fat-bearing cells may Int. J. Med. Sci. 2010, ... understand the crosstalk and interregulatory rela- tionships between chemokines and cytokines, mes- enchymal cells and adipocytes during the aging process, in particular during th...

Ngày tải lên : 08/08/2014, 18:20

14
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Báo cáo y học: "An open pilot study of zonisamide augmentation in major depressive patients not responding to a low dose trial with duloxetine: preliminary results on tolerability and clinical effects" ppsx

... details 1 Department of Neuroscience, Section of Psychiatry, University of Genova, Genoa, Italy. 2 Department of Hematology and Oncology, Section of Semeiotics and Medical Methodology I, University of Genova, ... study rath er aimed to investigate the role of the combination of the two drugs, and the unusual choice of the SNRI duloxetine (mainly metabolized by CYP1A...

Ngày tải lên : 09/08/2014, 01:21

8
560
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Báo cáo y học: "Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption" ppt

... inhibited and this led to a reduction in synovial hyperplasia and joint swelling with maintenance of joint integrity [31]. Similar results were obtained in an autoantibody-mediated murine model ... metalloproteinases (MMPs) are a family of 23 enzymes in man that facilitate turnover and breakdown of the ECM in both physiology and pathology. The MMP family con- tains the o...

Ngày tải lên : 09/08/2014, 06:22

10
386
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Báo cáo y học: "The 3rd International Meeting on Gene Therapy in Rheumatology and Orthopaedics" pot

... efficiently into cells by attaching protein transduction domains to their amino-termini. One such protein transduction domain is derived from the TAT protein of HIV; Jeffrey Marx (Medtronics Inc., Minneapolis, ... previous meeting in this series, and further clinical trials seem likely. Introduction Every 3 years, a loosely affiliated network of investigators holds an informal, 2-day...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: "Magnetic resonance imaging changes of sacroiliac joints in patients with recent-onset inflammatory back pain: inter-reader reliability and prevalence of abnormalities" potx

... likelihood of covering all kinds of abnormalities will increase by increasing patient number. The real value of MRI will therefore be ascertained in future, by following the patients longitudinally and ... 46 History of inflammatory bowel disease present (%) 15 History of uveitis present (%) 15 History of psoriasis present (%) 24 Family history of ankylosing spondylitis pr...

Ngày tải lên : 09/08/2014, 07:20

6
400
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$Báo cáo y học: "Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity" pot$

Báo cáo y học: "Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity" pot

... censoring at 4 years. Results Continuation rates of infliximab therapy Of the initial 511 patients enrolled in the study, 507 effectively started infliximab therapy. All patients had long-standing, active, ... primarily maintained to evaluate effectiveness and safety issues [27,28]. Evaluation of the efficacy of long-term therapy shows that, after 4 years of infliximab therapy,...

Ngày tải lên : 09/08/2014, 08:22

7
438
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Báo cáo y học: " High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis" ppsx

... inhibitor Apolipoprotein A α 1 -Antitrypsin PEDF Fibronectin Tetranectin Fibronectin Clustrin H 4 inhibitor α 1 -Antichymotrypsin Pregnancy zone protein Gelsolin α 1 -Acid glycoprotein Fibrinogen S100 Kinninogen ... cohort of 62 individuals, including healthy individuals and patients with early and late OA. Our results show clear differences in protein profiles between healthy...

Ngày tải lên : 09/08/2014, 10:20

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Báo cáo y học: "Cartilage preservation by inhibition of Janus kinase 3 in two rodent models of rheumatoid arthritis" doc

... efficacy produced by CP-690550 in the rodent models of arthritis may result from its ability to affect signaling of a number of cytokines including IL-2, -7, -15 and -21 as a con- sequence of JAK3 inhibition ... exhibited the safety liabilities associated with calcineurin inhibition, yet has demonstrated efficacy in a number of animal models including delayed-type hypersens...

Ngày tải lên : 09/08/2014, 10:22

9
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