Báo cáo y học: "Shadows on the wall" ppsx

... cells. is one may actually be on the way out, I’m glad to say, but all the biology and biochemistry textbooks I’m aware of still imply it, if they don’t say so directly. I suspect many scientists ... originators’ hype proclaimed they would be. I don’t mind trying such things out to see if they might be useful, but we seem utterly unable to pull the plug on them, or even phase them out gradually, ... and the ﬁre is a walkway along which people carrying things, including replicas of animals, pass continuously. All the people of the cave can ever see are the shadows cast on the wall in front...

Báo cáo y học: "Update on the treatment of ocular toxoplasmosis"

... survey of the opinion of oph-thalmic specialists in uveitis was performed recently by Gary Holland. [3] The reasons that were commonly accepted to introduce a therapy were the following: a) the ... lesion within the vascular arcades of the posterior pole (zone 1) b) the presence of a lesion in the proximity of the optic nerve or the macula c) or a severe inflammatory reaction within the ... primary infection. Disease evolution depends on many factors: the immune response of the host, the virulence of the parasite and environmental factors and ocular toxoplasmosis can heals spontaneously...

Tài liệu Báo cáo Y học: Studies on the nonmevalonate pathway of terpene biosynthesis The role of 2C-methyl-D -erythritol 2,4-cyclodiphosphate in plants docx

... 2C-methyl-D-erythritol4-phosphate can be converted into a cyclic diphosphate by the consecutive action of 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, 4-diphosphocytidyl-2C-methyl-D-erythritolkinase ... Stereochemistry of the isoprenylation oftryptophan catalyzed by 4-(g,g-dimethylallyl) tryptophan synthasefrom Claviceps, the first pathway-specific enzyme in ergot alkaloidbiosynthesis. J. Am. ... 6).DISCUSSION The conversion of 2C-methyl-D-erythritol 4-phosphate into the corresponding 2,4-cyclodiphosphate by the consecutiveaction of three recombinant E. coli enzymes (specified by the ispD,...

Báo cáo y học: "Report on the Molecular Approaches to Osteoarthritis Symposium, Imperial College London, UK, 18–20 April 2004" docx

... sequestered in the extracellular matrix,possibly by perlecan. Damaging the tissue by simplecutting releases the growth factor very rapidly andactivates the chondrocytes. bFGF upregulates synthesisof ... difficulty ofpredicting its progression. There is often disparitybetween the X-ray appearance and symptoms, and a lackof satisfactory markers for monitoring progression orresponses to therapy. ... collagen and proteoglycan by chondrocytes. MaryGoldring (Boston, MA, USA) has shown that the inhibitionof expression of type II collagen occurs at the transcriptional level. The mechanism is complex;...

Báo cáo y học: " Analysis on the clinical features of 22 basaloid squamous cell carcinoma of the lung" doc

... wassignificantly influenced by treatment mode and clinicalstage of the tumor. The post-operation mortality hazardof patients treat ed with a combination of chemotherapyand radiation therapy was 1.296 ... history,pulmonary function and the location of tumors [4]. The results of this study demonstrated that the mediansurvival time of basaloid squamous cell carcinoma andPDSC patients were 19 months ... clinicalstage of the tumor. The post-operation mortality hazardof patients treat ed with a combination of chemotherapyand radiotherapy was 1.296 times higher than othertreatment modes (p = 0.025). The...

Báo cáo y học: "Gout in the spotlight" ppsx

... place downstream of the MSU-inflammasomeinteraction or whether they take place concurrently. This toocan be addressed experimentally as the tools are currentlyavailable. The current data show ... practice, particularly in the elderly population withmultiple co-morbidities. Any new therapies that target the new inflammatory processes set off by MSU crystals willpotentially have a major impact ... for citation purposes)Arthritis Research & Therapy Vol 10 No 3 Soregulated molecules. A major question, in light of the findingsreported by Martinon and colleagues [3], is whether theseevents...

Báo cáo y học: "Impact of the Kenya post-election crisis on clinic attendance and medication adherence for HIV-infected children in western Kenya"

... them to go on the roads and try toget [to clinic]. The risks to personal safety were seen to vary based on the fam-ilies' tribal affiliation, their location, and whether they were in the ... contributed to the conception and design of the study, revised the manu-script critically, and gave final approval for publication.SEW contributed to the conception and design of the study, conducted ... decisions.None of the authors have any competing interests to dis-close.Authors' contributionsRCV had full access to all the data in the study and hadfinal responsibility for the decision...

Báo cáo y học: " Efficacy of the Valsalva Maneuver on Needle Projection Pain and Hemodynamic Responses During Spinal Puncture"

... orally on the morning of surgery. On arrival in the operating room, ECG electrodes and non-invasive blood pressure (NIBP) monitor were applied and oxygen saturation was monitored by pulse oxymeter. ... reduction of pain in balloon group compared with distraction and control groups.8 This study evaluated the efficacy of Valsalva maneuver on needle projection pain and hemody-namic responses ... Abstract This study evaluated the efficacy of the valsalva maneuver that can induce baroreceptor ac-tivation and nociception, on needle projection pain and hemodynamic responses associated with...

Tài liệu Báo cáo Y học: Mutations in the docking site for cytochrome c on the Paracoccus heme aa3 oxidase Electron entry and kinetic phases of the reaction pptx

... for the two-subunit wild-type complex confirms the contribution ofadditional charge(s) located on the two further subunits of the native oxidase.In focussing on the main interaction domain on ... indeedrelate to the early phases of electron entry. Using the cyanide-inhibited enzyme, the reaction sequence is limited to the transfer of the first two electrons reaching the CuA/hemea redox ... information is at hand for the docked complex, the interaction domain for cytochrome c on the cyto-chrome bc1complex of yeast turned out to be confined to afew residues only [33].Both the mutants...

Báo cáo Y học: Effect of the disease-causing mutations identiﬁed in human ribonuclease (RNase) H2 on the activities and stabilities of yeast RNase H2 and archaeal RNase HII pot

... interaction of the backbone atoms and the side-chain Cb atom [35,37–40]. This may be the reason why the mutation at Gly10 destabilizes the protein. Thus,Gly10 contributes to the stabilization of ... immunity.Of these mutations, the Gly37 ﬁ Ser mutation in the catalytic subunit (RNASEH2A) has been shown togreatly reduce enzymatic activity without seriouslyaffecting the stability of the complex ... whether other mutations in the accessory proteins (RNASEH2B and RNASEH2C)also reduce enzymatic activity without seriously affect-ing complex stability. In addition, the reason why the Gly37...

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