báo cáo khoa học: "Interest in quantitative genetics of Dutt’s and Deak’s methods for numerical computation of multivariate normal probability integrals" potx

... x0 y0 w1 h0" alt="" Interest in quantitative genetics of Dutt’s and Deak’s methods for numerical computation of multivariate normal probability integralsV. DUCROCQJ.J. COLLEAULN.R.A., ... correlated traits, for certain methods used to analyse discrete traits and for some studies on selection involving a limitednumber of candidates. Dutt’s and Deak’s methods can ... variable.Within this general framework, knowledge of the value of normal probability integrals if often required and consequently the scope of corresponding numerical methods is...

báo cáo khoa học: " Advances in the genetics of endometriosis" pptx

... are enzymes involved in the detoxiﬁcation of a broad range of toxic compounds and carcinogens, including dioxin [48]. Two of the most studied SNPs in detoxiﬁcation enzymes are in the GST genes ... in discovering the genetic basis of endo-metriosis are early detection and improved treatment of endometriosis-associated symptoms, including infertility and pelvic pain. GWASs may bring insight ... [35,39].Polymorphisms in cytokine genes, including tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6 and IL-10, and their receptors (IL-1RN and IL-2Rβ), have been extensively studied because of the involvement...

Báo cáo khoa học: "Adaptivity in Question Answering with User Modelling and a Dialogue Interface" pptx

... construct and update a model of the user’s interests, goals and level of under-standing. From a QA point of view, the main goal of the dialogue component is to provide users witha friendly interface ... processingWe perform query expansion, which consists in creating additional queries using question wordsynonyms in the purpose of increasing the recall of the search engine. Synonyms are obtained ... amount of linguistic processing appliedduring question processing and answer generation,while giving more relief to the post-retrieval phase and to the role of the UM.2 User modelDepending on...

Báo cáo khoa học: "atterns in individual growth, branch population dynamics, and growth and mortality of first-order branches of Betula platyphylla in northern Japan" docx

... a branch, and TBbmI:increment in total biomass of a branch) indicating thatbranch growth increased with increasing individualheight growth. In one regression (for FBbmI: increment in foliar ... FBbmI: increment in foliar bio-mass of a branch, WBbmI: increment in woody biomass of a branch, and TBbmI: increment in total biomass of abranch): larger branches in the upper part within individ-uals ... size and height of branches, the competitive status of individuals, and the size and growth of individuals.2. MATERIALS AND METHODS 2.1. Study site and data collectionAt the end of the growing...

báo cáo khoa học: "Updates in non-small cell lung cancer - insights from the 2009 45th annual meeting of the American Society of Clinical Oncology" potx

... taxanes due to inhibition of tubulindeacetylator HDAC and Platinum drugs by increasingDNA fragmentation in preclinical and phase I studies[43].Table 5: PFS and OS in Zodiac, Zeal, and Zest studies.TRIAL ... Egorin MJ, et al.: Phase I and pharmacokinetic study of vorinostat, a histone deacetylase inhibitor, in combination with carboplatin and paclitaxel for advanced solid malignancies. Clin Cancer ... as KRAS testing for making decisions in the first-line treatment setting cannot be recommended at thistime. Lastly, there is hope for improving outcomes in thesecond-line setting given the...

Báo cáo khoa học: Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (AriceptÒ) to cholinesterases doc

... of this class of inhibitors haveindicated that both the benzoyl containing functionality and the N-benzylpiperidine moiety are the key features for binding and inhibition of AChE. In the present ... Ala in Mo AChE, which results in again of binding energy suggesting that the bulky Tyr residuesterically hinders the binding of E2020 to AChE. This is alsoevident in the molecular model of ... gorge dimensions in accommodating bulky inhibitorswas also seen in the binding of propidium, decamethonium,tacrine and ethopropazine. The phenyl and the indanonerings in E2020 are ideally spaced...

báo cáo khoa học: " FCR (Fludarabine, Cyclophosphamide, Rituximab) regimen followed by 90yttrium ibritumomab tiuxetan consolidation for the treatment of relapsed grades 1 and 2 follicular lymphoma: a report of 9 cases" pot

... majority of patients during FCR treatment, and in all of them after90Y-RIT. Despite the high incidence of grade 3 or 4 neutropenia there were no patients requ ir-ing hospitalization for infection. ... setting of patients, specially at age of 60-75 and earlier in firstrelapse; further studies will help to clarify the best strat-egy for incorp orating R IT into the treatment algorithm of these ... rituximab) and after one year, at the second relapse, he received cyclo-phosphamide plus dexamethasone and rituximab,remaining in CR for 48 months. He died at 73 years of age for sepsis during support...

báo cáo khoa học: " Intestinal adhesion due to previous uterine surgery as a risk factor for delayed diagnosis of uterine rupture: a case report" pot

... her small intestine tightlycovered the anterior uterine wall, with bleedin g observedfrom the edge of the intestinal covering (Figure 1, arrow).After separating her small intestine, it became ... small intestine, uterine rupture becameevident; her small intestine covered and occluded the uterine rupture. Amniotic membrane beneath the rupture site remained intact.Kuwata et al. Journal of ... only causing the rupture but also masking it and thus preventing its early diagnosis.ConsentWritten informed consent was obtained from the patient for publicatio n of this case report and any...

báo cáo khoa học: "A simple technique to position patients with bilateral above-knee amputations for operative fixation of " docx

... patient is important in achieving and maintaining fracture reduction while notcausing skin injuries. Generally, the foot of the affectedlimb is put into a boot, and applying traction to thisFigure ... literature, and drafting the manuscript as the main author. AD was involved in reviewingthe literature and proofreading the manuscript. AD* critically revised themanuscript for important intellectual ... was involved in theconception of the study and revising the manuscript. All authors read and approved the final manuscript.Competing interestsThe authors declare that they have no competing interests.Received:...

báo cáo khoa học: "Changes in the distribution of the genetic variance of a quantitative trait in small populations of Drosophila melanogaster" docx

... 1977),fluctuating over generations or even diminishing in the remaining instances. For perform-within-line component of the genetic variance is directly estimated, its value diminisheswith ... 1955), and therefore segregatingloci affecting bristle number can be assumed to be initially in linkage equilibrium. Further-more, losses of lines during the period of inbreeding ... R; , and the mean and the variance of the distribution of the responsesobtained in different independent lines are R and V(Ri respectively. In each line, N individuals...

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