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Báo cáo y học: "No stone unturned" pot

Báo cáo y học:

Báo cáo y học: "No stone unturned" pot

... leaving no stone unturned in our efforts to find them a treatment. If we only do research that applies discoveries we already have made, we are only looking under stones that have already been turned. ... lamppost. A passerby offers to help and asks exactly where he lost them. “Over there,” he replies, pointing off into the darkness. “But then, why are you looking for them here?” says the puzzled ... here.”If the only kind of research we do is based on what we already know, we are looking where we already have light. If it turns out that’s where the keys are, fine. But we usually aren’t sure...
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Báo cáo y học:

Báo cáo y học: " No effect of short-term amino acid supplementation on variables related to skeletal muscle damage in 100 km ultra-runners - a randomized controlled trial" potx

... or carbohydrate plus casein hydrolysate (6% carbo-hydrate + 1.8% protein hydrolysate) 500 ml immediatelypre-exercise and every 5 km in the study of Saunderset al. [15]. In the study of Valentine ... kinase and myoglobin, remain increased for upto seven days after a marathon [ 38], they should bemeasured not only immediately after the race but alsoin the recovery phase. Presumably the intake ... Biotechnology, andBiochemistry 2003, 67:372-375.40. Buckley JD, Thomson RL, Coates AM, Howe PR, Denichilo MO, Rowney MK:Supplementation with a whey protein hydrolysate enhances recovery ofmuscle force-generating...
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Báo cáo y học: No associations of Helicobacter pylori infection and gastric atrophy with plasma total homocysteine in Japanes

Báo cáo y học: No associations of Helicobacter pylori infection and gastric atrophy with plasma total homocysteine in Japanes

... al. Homocysteine syn-thesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women. ... Hamajima N, et al. Associations between polymorphisms in the thymidylate synthase and serine hy-droxymethyltransferase genes and susceptibility to malignant lymphoma. Haematologica. 2003; 88: 159-66. ... and plasma total homocysteine according to genotypes of methylenetetrahydrofolate re-ductase (MTHFR) and thymidylate synthase (TS), H. pylori infection and gastric atrophy Table 3. Odds ratio...
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Báo cáo y học: "No increased risk of infant hypospadias after maternal use of loratadine in early pregnancy"

... with which apparent statistically significant increases have to be handled when no prior hypothesis exists. Key words: Hypospadias, loratadine, pregnancy, drug safety. 1. Introduction In a recent ... care in the country. Children with hypospadias will therefore be identified also when they, perhaps years after birth, undergo reconstructive surgery. A description of the system of ascertainment ... respectively) and a study from CDC, using data from the National Birth Defects Prevention Study [5], found no association in a retrospective case-control study of 563 infants with hypospadias...
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Báo cáo y học: "Comparison of osteogenic potentials of human rat BMP4 and BMP6 gene therapy using [E1-] and [E1-,E2b-] adenoviral vectors"

... from R&D Systems (Minneapolis, MN) and displayed two bands at 18 kD and 23 kD. This difference may be due to dissimilar cell types, which may produce different numbers of glycosylation sites. ... may be expressed by their adenoviral vectors in AN and SD rats, the osteogenic potentials of BMP4 or BMP6 are significantly reduced in immunocompetent rats. This limitation may be caused by ... osteogenic potential of direct BMP adenovirus vector gene therapy, the results of this study indicate that BMP gene therapy has unique characteristics and that the initial immune response may play...
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Báo cáo y học:

Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"

... would have very profound implications for human germline gene therapy. Gene transfer into embryos (using pronuclear microinjection or RVVs) is inherently very costly and technically demanding, ... Similarly, the pronuclei in ovine zygotes are very difficult to visualise, due to sharing a very similar refractive index with the cytoplasm; this necessitates the use of top-quality optics, ... contrast (DIC) microscopy, instead of standard phase contrast microscopy. Thus, empirical adjustments enable pronuclear microinjection to be employed with zygotes from essentially any mammal. It would...
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Tài liệu Báo cáo Y học: Antimicrobial dendrimeric peptides pot

Tài liệu Báo cáo Y học: Antimicrobial dendrimeric peptides pot

... 5200(RLYR)21950(RLYR)4338(RLYR)848Dendritic R4 (RLYR)2K 3700(RLYR)4K2K 1510(RLYR)8(K2K)2K 1514Dendritic R8 RLYRKVYG 3950(RLYRKVYG)2K 1420(RLYRKVYG)4K2K 610(RLYRKVYG)8(K2K)2K 112Tachyplesin 108928 ... determinedaccurately because o f its poor solubility in phosphatebuffers, this peptide rapidly and quantitatively inducederythrocytes aggregations.Proteolytic stabilityThe proteolytic stability of d ... attributes. They display potent and broad-spectrum activity under both low- and high-salt conditions,enhanced proteolytic stability and dec reased hemolyticactivity. Furthe rmore, they require...
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Báo cáo Y học: Mydj2 as a potent partner of hsc70 in mammalian cells doc

Báo cáo Y học: Mydj2 as a potent partner of hsc70 in mammalian cells doc

... 269) 1555cells, using a-hydroxy-farnesyl phosphonic acid, showedthat Mydj2, in agreement with previous studies [10,30] existsin two forms, a farnesylated and a nonfarnesylated one(data not shown).We ... the farnesylatedand the nonfarnesylated forms of Mydj2 protein by Westernblotting analysis, using the same anti-dj2 Ig as in immuno-fluorence experiments. As shown in F ig. 5 , Mydj2 does notseem ... and only t henonfarnesylated form is translocated to the nucleus.Association of cochaperones Mydj2 with Myhsc70The partner selectivity between chaperones and cochaper-ones is not entirely clear....
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Báo cáo Y học: C-labelling experiments potx

Báo cáo Y học: C-labelling experiments potx

... CO2Acetaladehyde fi acetateGlyceraldehyde 3-P fi glycerolFormation of Acetyl-CoA in the cytosolAcetate fi acetyl-CoA (cytosolic)Anaplerotic reaction (cytosolic)Pyruvate (cytosolic) + CO2fi ... 6-PEMP-pathwayGlucose 6-P fi fructose 6-P (reversible)Fructose 6-P fi 2 glyceraldehyde 3-PGlyceraldehyde 3-P fi phosphoenolpyruvatePhosphoenolpyruvate fi pyruvate (cytosolic)PP-pathwayGlucose ... N-ethoxycarbonyl amino acid ethylesters and N-(N¢,N¢-dimethyl)methylene amino acid ethylesters, were synthesized and analysed by GC-MS [4,13]. Themass spectra obtained from the GC-MS analysis...
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Báo cáo y học:

Báo cáo y học: "No aggression in a 4-year-old boy with an androgen-producing tumour: Case Repor" pdf

... in mammals. In The Physiology of Aggression and DefeatEdited by: Eleftheriou BE, Scott JP. New York: Plenum; 1971:43-63. 4. Moyer KE: The Psychobiology of Aggression New York: Harper & Row;1976. ... of anxiety, some behavioural problems, anddelayed speech development, the boy was referred to ouroutpatient unit for child and adolescent psychiatry. Atpsychiatric examination, January 2003, ... Sánchez-Martín et al.[19] examined 28 boys and 20 girls with a mean age of 4years by videotaping them every morning during free playin the classroom during 4 months. They found that higherlevels of...
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