Báo cáo y học: " Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts" ppt
Báo cáo y học: " Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts" ppt
... et al., Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibro-blasts Genome Biology 2010, 11:R5Mehta et al. Genome Biology 2010, ... nuclear actin:myosin motor function. Nuclear myosin 1β is required for chromosome territory repositioning in HDFs placed in low serum In an effort to elucidate which myosin isoform wasinvolved in chromosome ... requires nuclear myosin and actinFigure 7 Chromosome repositioning requires nuclear myosin and actin. The relocation of human chromosomes 10 and 18 after incubation in low serum is myosin and actin...
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Báo cáo y học: "DAS28 best reflects the physician''''s clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment" potx
... by eliminating variablesthat are already incorporated into the DAS28 (or are highlyrelated to them such as CRP and 68 tender joint and 66 swol-len joint count) and taking into account only ... evaluating insufficient response to infliximab therapy (especially in daily practice) andthat this variable can only slightly be improved by adding sup-plemental variables.DAS was developed in ... measured to best evaluate theeffect of therapy and remaining disease activity in daily prac-tice (and in clinical trials). The aim of the present analyses was to evaluate whether the decision to increase...
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Báo cáo y học: " Differential toll-like receptor 3 (TLR3) expression and apoptotic response to TLR3 agonist in human neuroblastoma cells" docx
... Ganglioneuroblastoma; (IRF3):Interferon regulatory factor 3; (NB): Neuroblastoma; (PKR): Double-strandedRNA-dependent protein kinase; (poly(I:C): Polyinosinic-p olycytidylic acid);(TLR): Toll-like receptor.AcknowledgementsThis ... TLR3agonist, polyinosinic-polycytidylic acid (poly(I:C)), on the growth of human NB cells was evaluated by WST-1 cellproliferation assay, flow cytometry analysis, and immunoblot analysis. Blockade ... implicated in the selective cytotoxicity of TLR3 agonist towards high TLR3-expressing NBcells.Keywords: neuroblastoma, toll-like receptor 3, poly(I:C), apoptosisIntroductionNeuroblastoma (NB)...
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Báo cáo y học: "Weight loss, leukopenia and thrombocytopenia associated with sustained virologic response to Hepatitis C treatmen"
... risk factors for acquiring HCV infection were related to injection drug use and tattooing. Mild and moder-ate liver inflammation determined by Knodell score was presented in the majority of patients ... regarding the influence of on-treatment factors during therapy. The purpose of our analysis was to identify clinical, biological, vi-rological and histological predictive factors that may be ... combined pegylated interferon alfa-2a or alfa-2b plus ribavirin. Genotypes of HCV were defined using the Bayer TRUGENE HCV Genotyping Test. Serum concentra-tion of HCV RNA was determined...
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Báo cáo Y học: A new conceptual framework for enzyme catalysis Hydrogen tunneling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes docx
... used asa tool for (a) increasing the catalytic efficiency of enzymes in the biotechnology industry (by enhancing the coupling ofdynamics to the reaction coordinate), and (b) producingmore effective ... nss4@le.ac.ukAbbreviations:TST,transitionstatetheory;TTQ,tryptophantrypto-phylquinone; MADH, methylamine dehydrogenase; AADH, aroma-tic amine dehydrogenase; TMADH, trimethylamine dehydrogenase;TSOX, heterotetrameric sarcosine dehydrogenase; ... enzyme inhibitors in the pharmaceuticalindustry (by dampening those vibrations coupled to thereaction coordinate). Such advances have broader implica-tions, as they will also give insight into...
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Báo cáo y học: "Advanced glycation end-product (AGE)-damaged IgG and IgM autoantibodies to IgG-AGE in patients with early synovitis." ppt
... is induced by AGE,can contribute to the inflammatory cycle by the inductionof proinflammatory cytokines, via the nuclear factor-κBpathway [21]. No studies have yet examined RAGEexpression in ... Nε-(car-boxymethly)lysine (50 mg/ml) inhibited the binding of poly-clonal anti-IgG-AGE antibodies to IgG-AGE by 40% butdid not inhibit RF binding to IgG. Lysine at the same con-centration did not inhibit ... with the inflammatory response, whereas anti-AGE-IgG is associated with rheumatoid factor positiverheumatoid arthritis in the early synovitis cohort at the initial visit Serum findingCharacteristic...
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Báo cáo y học: "Phenotypic and functional characterisation of CD4+ memory T cells homing to the joints in juvenile idiopathic arthritis" pps
... a functional point of view, chemokines can be broadlyclassified into two groups: inflammatory and homeostatic[4]. The inflammatory chemokines are induced by proin-flammatory stimuli and control ... neogenesis by a lymphotoxin-dependent mechanism or recruit T cells to the inflamed tissues by a lymphotoxin-independentmechanism.Taken together, our findings suggest that CCR7+ memoryT cells ... expression ofCCR7 in memory T cells homing to the synovial microenvi-ronment in relation to expression of the inflammatory chem-okine receptors CCR5 and CXCR3. In this study we therefore investigated...
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Báo cáo y học: "Interactions between IL-32 and tumor necrosis factor alpha contribute to the exacerbation of immune-inflammatory diseases" ppt
... 3Inflammatory cytokines were induced by human IL-32β in miceInflammatory cytokines were induced by human IL-32β in mice. (a) Raw 267.4 was cultured with the supernatant of human IL-32β (h IL-32β) ... generally dependent on the TNFα-inducing effect in these mouse models of inflammatory diseases.DiscussionTNFα is a potent proinflammatory cytokine related to thepathogenesis of inflammatory diseases ... expression wasprominent in the synovial tissues of rheumatoid arthritis patients,especially in synovial-infiltrated lymphocytes by in situhybridization. To examine the in vivo relationship...
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Báo cáo Y học: Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N1,N11-diethylnorspermine pdf
... N1,N11-diethylnorspermine (DENSPM) which induces a rapid depletion o f all polyamines by downregulating the activity of the biosynthetic e nzymes and upregulating the activity ofthe catabolic enzyme ... the induction of SSAT results in the acetylation ofspermine and spermidine, which are subsequently oxidized by polyamine oxidase to form spermidine and putrescine,respectively. In addition, stoichiometric ... SSAT in the sonicate was deter-mined by measuring the synthesis of [14C]acetylspermidineafter incubation with [14C]acetyl coenzyme A and spermi-dine [20].Flow cytometry and data analysisCells...
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnbáo cáo khoa học y họcbáo cáo y tế học đườngmẫu báo cáo y tế học đườngbáo cáo y tế học đường cuối nămNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Thơ nôm tứ tuyệt trào phúng hồ xuân hươngSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀM