Báo cáo y học: "START lipid/sterol-binding domains are amplified in plants and are predominantly associated with homeodomain transcription factors" potx
... lipid/sterol-binding domains are amplified in plants and are predominantly associated with homeodomain transcription factors<p>A survey of proteins containing lipid/sterol-binding StAR-related ... lipid/sterol-binding domains are amplified in plants and are
predominantly associated with homeodomain transcription factors
Kathrin Schri...
... erosive disease,
including large joint involvement, and were refractory to com-
bination therapy with DMARDs and, in four patients, with
tumour necrosis factor (TNF)-blocking agents. Heparinized
whole ... treatment and compared with the avidity of TT
antibodies following repeated immunizations. Synovial biopsies
were obtained by arthroscopy before HDC plus HSCT, and
analyzed by...
... complementarity-determin-
ing region (CDR3)- typing of T cells infiltrating the joints has
been used, aiming to identify clones that are specifically
enriched in the inflamed synovia. Some CDR3- ... cells) are
shown. (Panel a) Treg cells are 1.33% and 2.9% in the total lymphocyte population and within the CD4
+
subset, respectively. (Panel b) Treg cells
are efficiently rem...
... recording information on
critical care resources, including the timing of introduction of
METs. In addition, ANZICS maintains an Adult Patient Data-
base (ANZICS-APD), which currently contains information ... undertaken using the
information contained within the database.
Assessment on timing of introduction of MET service
We obtained information from a database maintained by the
ANZICS ARC...
... Sp3.
Receptor tyrosine kinases (RTKs) are cell surface receptors
that contain intrinsic protein tyrosine kinase activity in their
cytoplasmic regions. They are responsible for transmitting
signals from ... activity in TM4 cells. Within this region, four
protein-binding sites were detected by DNase I footprinting
and gel shift assays. Three of them contained Sp1 cis-acting
motifs, wh...
... abundantly in
lactating mammary glands and is secreted in association with
fat globules. This protein consists of two-repeated EGF-l ike
domains, a mucin-like domain and two-repeated discoidin-
like domains ... detected
in various other tissues, including brain, lung, heart, kidney
and spleen in some mammals such as mouse, human and
bovine [7–9]. The mouse and bovine MF...
... not
necessarily result in similar changes at the protein level and
indicate that UCP3 density in SS and IMF mitochondria can
be differently affected by metabolic changes.
Keywords: fasting; intermyofibrillar ... Kuhne,
Pierre Flandin, Jean-Paul Giacobino and Patrick Muzzin
Department of Medical Biochemistry, Faculty of Medicine, University of Geneva, Switzerland
Uncoupling protein-3 (U...
... leaving TNFα-
induced NF-κB activation intact. ER-retained oligomers may
independently activate novel signalling pathways leading to
inflammation, may modify ER stress-induced responses, or may ... studied.
Conversely, the effect of TNFR1 mutations outside immune
cells also needs to be examined. Understanding the signalling
pathways connecting protein misfolding and inflammation will
be int...
... 'sympathetically maintained pain'
[5].
Naturally occurring sympathetic neurotransmitters are cate-
cholamines known as norepinephrine, epinephrine, and
dopamine. All three substances act within the ... Diatchenko and
colleagues [10] also demonstrated that COMT inhibition in
rats results in a dramatic increase in sensitivity to pain. Low
COMT activity may increase pain se...
... concentrations,
respectively, are modulated by hormones and neuronal
pathways coordinated by a subordinate neuroendocrine
centre in the hypothalamus, which follows a strict 24-hour
daily cycle.
The closest similarity with ... diseases
[16].
Insights into neurohormonal effects of
melatonin in autoimmunity
MLT is an important neurohormone mainly synthesized by the
pineal gland with...