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Population genetic variation in gene expression is associated with phenotypic variation in Saccharomyces cerevisiae pdf

Population genetic variation in gene expression is associated with phenotypic variation in Saccharomyces cerevisiae pdf

Population genetic variation in gene expression is associated with phenotypic variation in Saccharomyces cerevisiae pdf

... Access2004Fayet al.Volume 5, Issue 4, Article R26Research Population genetic variation in gene expression is associated with phenotypic variation in Saccharomyces cerevisiae Justin C Fay*§, Heather ... expression is associated with phenotypic variation in Saccharomyces cerevisiaeThe relationship between genetic variation in gene expression and phenotypic variation observable in nature is not well understood. ... of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL. Population genetic variation in gene expression is associated...
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Báo cáo y học: "Complete suppression of viral gene expression is associated with the onset and progression of lymphoid malignancy: observations in Bovine Leukemia Virus-infected sheep" pdf

... silencing of viralgenes, including the oncoprotein Tax, is associated with tumor onset.Conclusion: Our findings suggest that silencing is critical for tumor progression and identify two distinctmechanisms -genetic ... these findings suggest that besides genetic changes, epigenetic mechanisms such as DNAmethylation and chromatin modifications might beinvolved in tumor -associated virus latency.DiscussionUsing ... of genetic alterations in the proviral genome. This independ-ent observation reinforces our previous conclusion andsuggests that besides genetic alterations, epigenetic mech-anisms might be involved...
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báo cáo khoa học: " Adiponectin receptor-1 expression is associated with good prognosis in gastric cancer" pptx

... expression expression is associated with is associated with is associated with is associated with good good good good prognosis in prognosis in prognosis in prognosis in gastric cancer gastric ... performed in triplicate. Immunohistochemical stainingImmunohistochemical stainingImmunohistochemical stainingImmunohistochemical staining All surgically obtained specimens were fixed in ... of adiponectin in cancer etiology is not yet fully understood. Although adiponectin may provide indirect protection against carcinogenesis by affecting insulin sensitivity and inflammatory...
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Báo cáo y học: "Transition of healthy to diseased synovial tissue in rheumatoid arthritis is associated with gain of mesenchymal/fibrotic characteristics" pdf

... α-smaFigure 1Haematoxylin and eosin staining on healthy and arthritic synovial tissueHaematoxylin and eosin staining on healthy and arthritic synovial tissue. Haematoxylin and eosin staining was performed ... both thelining and the sublining adjacent to the lining. This same stain-ing pattern is found for collagen type IV. This observationimplies that, in RA patients, cells from the lining layer ... with haematoxylin and eosin showed an increase in the number ofcell layers of the synovial lining of RA patients (Figure 1). E-cadherin staining was found in the healthy synovium, espe-cially in the lining...
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Báo cáo y học: "Estrogen receptor-α gene haplotype is associated with primary knee osteoarthritis in Korean population" docx

... OA, and genetic variations in the ER-α gene may be involved in OA.Keywords: estrogen receptor, haplotype, knee osteoarthritis, polymorphismIntroductionOsteoarthritis (OA) is a common disorder ... BtgI polymorphism (codon 594) in the ER-α gene and ER-α haplotypes of three polymorphisms (PvuII in intron 1, XbaI in intron 1, and BtgI in exon 8) with primaryknee OA in the Korean population. ... mechanisms in osteoarthritis.Best Pract Res Clin Rheumatol 2001, 15:693-709.2. Reginato AM, Olsen BR: The role of structural genes in thepathogenesis of osteoarthritic disorders. Arthritis Res...
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Báo cáo khoa học: "Weak expression of cyclooxygenase-2 is associated with poorer outcome in endemic nasopharyngeal carcinoma: analysis of data rom randomized trial between radiation alone versus concurrent chemo-radiation (SQNP-01)" pdf

... 1–4, weak staining; 5–8, moderate staining;and 9–12, strong staining. For the purpose of statisticalanalysis, the cohort was grouped into tumors with negli-gible or weak staining (N = 34) ... and cisplatin.Of the 221 patients, 88 were referred for treatment from asingle institution following initial diagnosis of NPC. Forlogistic reasons, only patients from this hospital wereincluded ... wasused to determine the level of COX-2 expression. A singlehead and neck histopathologist was assigned to performthe scoring. She was blinded to all patient characteristicsincluding the treatment...
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Báo cáo y học: "The ITGAV rs3738919-C allele is associated with rheumatoid arthritis in the European Caucasian population: a family-based study" docx

... vitronec-tin, fibronectin, osteopontin, sialoprotein, thrombospondin,fibrinogen, von Willebrand factor, tenascin, agrin, matrix metal-loproteinases, and prothrombin) [6]. The integrins are involved in ... reproduction in any medium, provided the original work is properly cited.AbstractThe integrin αvβ3, whose αv subunit is encoded by the ITGAV gene, plays a key role in angiogenesis. Hyperangiogenesis is involved ... genome-wide linkage analysis of rheumatoid arthritisincluding covariates. Arthritis Rheum 2004, 50:2757-2765.6. Eliceiri BP, Cherech DA: The role of alphav integrins duringangiogenesis: insights into...
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Báo cáo y học: "Deficiency in mouse Y chromosome long arm gene complement is associated with sperm DNA damag" pdf

... must arise during spermiogenesis since this is when the NPYq-encoded genes are expressed in nor-mal mice [3,5,28]. In keeping with the two step modelfor the generation of DNA damage in epididymal ... compac-tion. In addition to demonstrating the involvement ofNPYq-encoded genes in regulating chromatin remodel-ing during spermiogenesis, the study also providesimportant insights into the regulation ... =0.000001) in the analysis of the three NPY-deficient geno-types in a single ANOVA, with aberration rate increasing with the extent of NPYq deficiency. However, this increasewas predominantly seen with...
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Báo cáo y học: "Deficiency in mouse Y chromosome long arm gene complement is associated with sperm DNA damag" pptx

... Bayesian sta-tistics that allows the integration of data fromheterogeneous sources. Integration is important because with expression data alone it is difficult to distinguishdirect from indirect ... Wehave also integrated information about binding motifs atpromoters. Doubtless, the dominant feature in our classi-fication is gene expression. This is, however, rather spe-cific and more informative ... expression, we inte-grated our data together with other published datasets todetermine the targets of Mbp1 and Swi4. This hasallowed us to distinguish direct targets of Cln3 fromgenes induced indirectly...
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Báo cáo y học: "High nuclear expression of STAT3 is associated with unfavorable prognosis in diffuse large B-cell lymphoma" doc

... nuclear staining of STAT3, and 24 cases (32.4%) with strong nuclear staining of P-STAT3. Representativestaining outcomes were shown in Figure 1. Thereexisted a consistence between the STAT3 expression and ... angiogenesis [11]. Hypermethylationsilencing of SOCS (the Suppressor of Cytokine Signal-ing) genes leads to reactivation of STAT pathway,resulting in the resistance to ABT-869, a pr omisingmulti-targeted ... Peking University School of Oncology, BeijingCancer Hospital & Institute; Key Laboratory of Carcinogenesis andTranslational Research (Ministry of Education); Beijing 100142, ChinaFull list...
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