... dinucleotides and silencesgene expression [26–28]. Furthermore, the interaction wasspecific for MBD1, as we failed to detect any interaction between p59 OASL and other members of the MBD familyusing the ... [12]. The products of these three genesare known, respectively, as the small (p42/p46), the medium(p69/p71) and the large (p100) forms of OAS [13], all ofwhich are enzymatically active. The ... human UbTo investigate whether the p59 OASL–MBD1 interaction isspecific for the UbL of p59 OASL and not Ub in general, weperformed a pull-down assay between monomeric Ub and MBD1 (Fig. 7).35S-labeled...