... that requires further study, up to and including biopsy. Soft, flat, submandibular nodes (< ;1 cm) are often palpable in healthy children and young adults, and healthy adults may have palpable ... simplex, herpesvirus-6, varicella-zoster virus, rubella, measles, adenovirus, HIV, epidemic keratoconjunctivitis, vaccinia, herpesvirus-8 b. Bacterial—streptococci, staphylococci, cat-scratch disease, ... disease) f. Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Table 6 0 -1 Diseases Associated with Lymphadenopathy 1. Infectious diseases a. Viral—infectious mononucleosis syndromes...