... 0 .24 seconds).However, caution should be used in acute inferior-wall MI to avoid possiblebradycardia. A common dosage is three 5-mg boluses of intravenous metoprolol 22 0 The Intensive Care Manual ch09.qxd ... Yusef S, et al. Effects of angiotensin-converting-enzyme inhibitor, ramipril, on cardio-vascular events in high-risk patients (The HOPE Study). NEJM, 20 00;3 42( 3):145–153.4. Hochman JE, Sleeper ... responses, despite the plethora of diseases that inflict humankind. 22 8 The Intensive Care Manual ch10.qxd 11/7/01 4:16 PM Page 22 8• Diabetic hemorrhagic retinopathy• Pregnancy• History of chronic...