Báo cáo y học: "Dichloroacetate alleviates development of collagen II-induced arthritis in female DBA/1 mice" pot
Báo cáo y học: "Dichloroacetate alleviates development of collagen II-induced arthritis in female DBA/1 mice" pot
... impact on in vivo inflammatory immune response. (a) IgG anti -collagen II antibody levels from the DCA-drinking group and the water-drinking group. (b) Serum pro-inflammatory cytokine intereukin-6 ... analyses.Clinical evaluation of arthritis All of the DBA/1 mice were inspected every second or thirdday after booster to assess the presence of arthritis. To evalu-ate the intensity of arthritis, ... the incidence and the progression of RA in BMD: bone mineral density; CII: collagen II; CIA: collagen II-induced arthritis; DCA: dichloroacetate; DTH: delayed-type hypersensitivity; IL: inter-leukin;...
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Tài liệu Báo cáo Y học: Presence and regulation of the endocannabinoid system in human dendritic cells potx
... 2-arachidonoylglycerol (2-AG), the cannabinoid CB1and CB2receptors, and one of the enzymes mostlyresponsible for endocannabinoid hydrolysis, the fatty acidamide hydrolase (FAAH). By using a very ... cells, arethe most potent antigen-presenting cells of the immunesystem. They play a central role in the initiation of primaryimmune response and in the enhancement of secondaryimmune response ... against infectiousagents [7,8]. A modulation of the cytokine network and adecrease of T- and B-cell proliferation have been described in vitro [9]. A reduction of the cytolytic activity of...
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Báo cáo y học: "Intraoperative device closure of atrial septal defects in the Older Population" pot
... remained 100%at 1 year’s follow-up.Minor complications were encountered in somepatients, including transient arrhythmia(n = 5) in thecourse of the device deployment. Temporary sinus bra-dycardia, ... withoutCardiopulmonary Bypass. Asian Cardiovasc Thorac Ann 2007, 15:191-193.11. Li GS, Kong GM, Wang YL, Jin YP, Ji QS, Li JF, You BA, Zhang Y: Safety andEfficacy of Transcatheter Closure of Atrial Septal ... associated withmidline sternotomy and cardiopulmonary bypass in alonger hospital stay. The midline incisions would alsoreserve the physical and psychological trauma for thepatients in their future....
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Báo cáo y học: "Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections"
... 14distress syndrome within 30 days following inclusion.The secondary endpoint was overall survival within 30days following study inclusion. Outcomes were assessedduring hospital stay at days 3, ... values.The development of sepsis from a localized infection isa dynamic continuum and in the majority a sequelae of CAP [54]. The severity of a disease determines the con-sumption of costly and ... available in 94.8% of patients. The most frequently missing covariate con-tained in the CURB65 score was urea which was missing in 19.1% of patients, primarily because it was only rarelymeasured in...
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Báo cáo y học: "The evolving story of medical emergency teams in quality improvement"
... distinct career pathway. Involving such physicians in medicalemergency teams will likely facilitate the dual roles of these as aclinical outreach arm of the intensive care unit and in identifyingproblems ... higherthan routine incident-reporting systems, but without requiringsubstantial investments of additional resources. Academic centersare increasingly recognizing engagement in quality improvement ... for the development of METs rose from observations that, in the majority of patients, premonitory signs and symptoms of cardio-pulmonary instability are often present hours before clinicaldeterioration...
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Báo cáo y học: "Aplasia and Agenesis of the Frontal Sinus in Turkish Individuals: A Retrospective Study Using Dental Volumetric Tomograph"
... drainage system of the frontal sinus depends on its embryologic development [2,13]. The drainage usually occurs directly into the frontal recess [14] or into the frontal recess by way of rudimentary ... of the case in women. In addition, the authors also reported that a greater frequency of unilateral agenesis of the sinus occurs among females. In contrast with the study performed by Aydinlioğlu ... age of 8 years, the top of the frontal sinuses is at the level of the orbital roof, and by the age of 10 years, the sinuses extend into the vertical portion of the frontal bone. The final adult...
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Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf
... wereresidues Gly261 and Gly262. The replacement of Gly262 byAla resulted in an inactive enzyme. Substitution of Gly261by Ala resulted to an enzyme with lower stability andincreased energy of activation. ... Bouriotis1,21Department of Biology, Division of Applied Biology and Biotechnology, University of Crete, Greece;2Institute of Molecular Biologyand Biotechnology (IMBB), Enzyme Technology Division, and the3Institute ... respectively. By introducing an Ala residue in the place of Gly it is expected that the conformational flexibility of themain chain can be constrained with a minimum perturba-tion of the local...
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Báo cáo Y học: Rum1, an inhibitor of cyclin-dependent kinase in fission yeast, is negatively regulated by mitogen-activated protein kinase-mediated phosphorylation at Ser and Thr residues pptx
... noteworthy that these B-typecyclins are strictly regulated in terms of protein amountsduring cell cycling by transcription and ubiquitin-mediatedproteolysis [11]. Second, the kinase activity of ... phosphorylation-initiated ubiquitinatio-nation of p25rum1 in G1phase play a role in setting athreshold of cyclin levels important in determining thelength of the pre-Start G1phase and in ensuring ... assay In this study, mainly two types of in vitro kinase assay wereperformed. First, we examined whether MAPK phosphory-lates p25rum1by in vitro kinase assay. GST-p25rum1fusionproteins were bound...
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Báo cáo Y học: Isolation and characterization of MUC15, a novel cell membrane-associated mucin pot
... employed analysing pro-tein samples by SDS/PAGE using 18% polyacrylamidegels, and for the staining of proteins using CoomassieBrilliant Blue R-250 and PAS reagent.Peptide mapping of bovine ... phenylthiohydantoinderivatives. N-glycosylation sites were assigned to aspara-gine residues lacking an identifiable phenylthiohydantoinderivative during amino-acid sequencing of glycosylatedsamplesorshowingupasasparticacidinPNGaseFtreatedMUC15 ... identification of N-glycosylation sites during amino-acid sequencing, asan Asp-phenylthiohydantoin derivative is seen instead of the unidentifiable glycosylated asparagine derivative. Fol-lowing sequence...
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Báo cáo y học: "Prevalence and correlates of being bullied among in-school adolescents in Beijing: results from the 2003 Beijing Global" docx
... bullying was defined. Bullying com-prises different forms including verbal (such as beingmade fun of, and teasing) and physical forms (such as hit-ting, kicking, pushing, and being locked indoors) ... study reports an overall prevalence of being bulliedover the past 30 days to the survey among Beijing students of 20%. Males were more likely to have reported beingvictims of bullying than females ... SSconducted a re-analysis of data, participated in the inter-pretation of results, and drafting of the manuscript. ASMparticipated in the interpretation of the results, and draft-ing of the manuscript....
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