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Báo cáo y học: "Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link" docx

Báo cáo y học:

Báo cáo y học: "Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link" docx

... 1Theories on the causal association between hyperuricemia and selected cardiovascular diseases. Simple causal diagrams on the associationbetween hyperuricemia and selected cardiovascular diseases. ... women after adjustment for cardiovascular risk factors and diuretic use. These resultsraised the question of an association of serum urate with cardiovascular disease and cardiovascular death ... probablyconfounded by other factors in the cardiovascular disease causal pathway [8].Several large epidemiological studies investigating the association between serum urate levels and cardiovascular mortality...
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Báo cáo y học: "Specifying and reporting complex behaviour change interventions: the need for a scientific method" potx

... controlled trials (RCTs) that are theoretically and methodologically consistent across studies, Bloom hassuggested meta-analytic strategies to take advantage ofnaturally-occurring variations in ... includeproviding a consistent and generalisable frameworkwithin which to gather evidence; promoting the under-standing of causal mechanisms that both enrich theory and facilitate the development ... concepts in the theory) that arecausally related to behaviour, and are therefore appropri-ate targets for the intervention, can confer a range of ben-efits including potentially stronger effects...
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Báo cáo y học: " Facilitators and obstacles in pre-hospital medical response to earthquakes: a qualitative study"

... Tsunami in Thailand and Indonesia [27,43], the Chi-Chi earthquake in Taiwan [16,39] and the Gujaratearthquake in India [44].As demonstrated, the army plays an important part in the early response ... evacuated mainly by air.It was the air force’s responsibility, along with the airtransport organization, to provide the evacuation by air.In addition they carried managers, medical teams and equipment ... this airport.”Another participant added that “Theairforceandairtransport organization concentrated all efforts on estab-lishing a reliable evacuation path by air from Bam to the rest of the...
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Báo cáo Y học: Ontogeny and subcellular localization of rat liver mitochondrial branched chain amino-acid aminotransferase docx

Báo cáo Y học: Ontogeny and subcellular localization of rat liver mitochondrial branched chain amino-acid aminotransferase docx

... fetal hepatocytes and the presence of an active and inactive form of the BCATm infetal and adult liver, respectively.MATERIALS AND METHODSFetal liversWistar rats of 17- and 19-days gestation ... [9,12].Isolation of total RNA and Northern blot analysisTotal RNA was isolated from liver, heart, or placentaaccording to Chomczynski and Sacchi [15]. For Northernanalysis, 20 mg RNA was subjected ... ontogeny. The branched-chain amino acids (BCAA) leucine, iso-leucine, and valine are required mainly for body proteinsynthesis. The initial enzymes for catabolism of the BCAAare regulated differently...
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Báo cáo y học: "Chondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subchondral bone osteoblasts: a basic science study" pptx

... 5'-GTT-TACTTTGGTGCCAGG (antisense) and 5'-GCTTGAAACATAGGAGCTG (sense) (OPG), 5'-GGGTAT-GAGAACTTGGGATT (antisense) and 5'-CACTATTAAT-GCCACCGAC (sense) (RANKL), and 5'-CAGAACATCATCCCTGCCTCT ... participated in study design, analysis and interpretationof data, manuscript preparation, and statistical analysis. SKTparticipated in study design, acquisition of data, analysis and interpretation ... of data, manuscript preparation, and statisticalanalysis. JV and EM participated in study design. DL partici-pated in acquisition, analysis, and interpretation of data. HF and ML participated...
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Báo cáo y học: "omparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi" pps

... glycolysis, tricarboxylic acid cycle,glyoxylate cycle, pentose phosphate shunt, and synthesisof all 20 standard a mino acids and the five nucleic acidbases. Moreover, dermatophytes appear ... (Eurotiales), Coccidioides and Histo-plasma (Onygenales) the mating type (MAT) loci areflanked by APN2 and the SLA2 genes encoding a DNAlyase and a cytoskeleton protein, respectively [37]. The MAT ... ×104conidia/ml and shaken at 180 rpm for three days at30°C. Total RNA was isolated using a commercial kitas described by the manufacturer (Qiagen, Hilden,Germany). After RNA extraction, a cDNA librarywas...
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Báo cáo y học: "Preformulation and stability in biological fluids of the retrocyclin RC-101, a potential anti-HIV topical microbicide/; potx

... transition sepa-rately, and peak areas were manually tabulatedStatistical analysisHPLC data obtained from the preformulation studieswere expressed as the average percentage of the peakarea ... Day and Dr. Manimalha Balasubramani at the Genomics and Proteomics Core Laboratories at the University ofPittsburgh for the assistance provided for the MALDI-TOF MS analysis. LornaRabe and ... Barcic, MaryMcQueen, Kathy Laychak, and Cindy Schatzman from the Magee-WomensClinical & Translational Research Center (CTRC) for all the assistanceprovided. Lindsay Ferguson, Yardlee Kauffman,...
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Báo cáo y học:

Báo cáo y học: " Pathogenesis of rheumatoid arthritis: how early is early" pdf

... helper type 1 cellscontribute to the perpetuation of disease. However, there is noguarantee that the mechanisms of late disease are identical to veryearly rheumatoid arthritis. Evaluation of the ... to the resolution. In this context, the study by Raza and colleagues raises questions about the role of T cells inRA and other forms of inflammatory arthritis.Many studies have suggested that ... pushed even earlier, perhaps to the preclinical phase.CommentaryPathogenesis of rheumatoid arthritis: how early is early?Gary S FiresteinDivision of Rheumatology, Allergy and Immunology, UCSD...
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Báo cáo y học: "Wildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in mice" pps

... activity and provide a cautionary tale for genetically uncontrolled studies.Background The epidermal growth factor receptor (EGFR) pathwayplays key roles in the development and maintenance ofmany ... HomozygousEgfrwa2 mutant and wildtype littermates were evaluated for defects in locomotor and maskingbehaviors.Results: Mice homozygous for Egfrwa2 showed normal daily locomotor activity and ... within the hypothalamus and is considered the primary anatomicalcircadian clock, and are associated with circadian time-Published: 16 November 2006Journal of Circadian Rhythms 2006, 4:15 doi:10.1186/1740-3391-4-15Received:...
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Báo cáo y học:

Báo cáo y học: " Treatment of forefoot problems in older people: study protocol for a randomised clinical trial comparing podiatric treatment to standardised shoe advi" potx

... [http://nhg.artsennet.nl/kenniscentrum/k_richtlijnen/k_nhgstandaarden/Samenvattingskaartje-NHGStandaard/M01_svk.htm].17. Garrow AP, Papageorgiou AC, Silman AJ, Thomas E, Jayson MI,Macfarlane GJ: Development and validation of a questionnaire to assessdisabling ... their assessment, and whether adequate deci-sions are made regarding treatment. For this evaluation, the notes of the podiatrists and the results of the entranceexamination will be made available ... Bothprimary and secondary outcome measures will be col-lected at baseline and after 3, 6, 9, and 12 months. Dataon personal education and work history, shoe history and co-morbidity[28] are collected...
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