Báo cáo y học: "Predicting the future of anti-tumor necrosis factor therapy" potx
Báo cáo y học: "Predicting the future of anti-tumor necrosis factor therapy" potx
... informa-tive sets of genes whose expression changes during therapyEditorialPredicting the future of anti-tumor necrosis factor therapyCornelis L VerweijDivision of Inflammatory Disease Profiling, ... costs for therapy, there isa strong need to make predictions on success before the start of therapy. In the current issue of Arthritis Research & Therapy,Hueber and colleagues become the first ... Essentially, twophases of unresponsiveness might be identified: a primaryphase directly after the start of treatment and a secondaryphase that develops in initial responders during the course of therapy....
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Báo cáo y học: "Demonstrating the benefit of medical emergency teams (MET) proves more difficult than anticipated"
... anticipated. These factors significantly reduced the power of the study. Based on their findings, the authors estimate that more than 100 hospitals would be needed to show the 30% difference they sought. ... goal of identifying and treating patients early in the course of their illness is preferable to waiting until more serious signs and symptoms have developed. Certainly, at the University of ... underpowered, the results of this study provide a reliable basis for the design of future studies. While we cannot definitively say that MET systems improve outcomes, it seems self-evident that the...
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Tài liệu Báo cáo khoa học: "Predicting the fluency of text with shallow structural features: case studies of machine translation and human-written text" doc
... indepen-dent of each other. Fluency was judged directly by the assessors, while adequacy was meant to assess the content of the sentence compared to a humangold-standard. Yet, the assessments of the ... influenced by manyfactors. The way the sentence fits in the con-text of surrounding sentences is one obvious factor (Barzilay and Lapata, 2008). Another well-known factor is vocabulary use: the presence ... were often the same—readability/fluency of the sentence is important for understanding the sentence. Only after the assessor has understood the sentence can (s)he judge how it compares to the human...
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Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf
... although the HGGG loop was acritical structural element for the catalytic efficiency of the enzyme, the cold adaptation of the enzyme could not beattributed to the presence of the Gly cluster ... G261A/ Y2 69A designed on the basis of side-chain packing criteriafrom a modelled structure of the enzyme resulted in restor-ation of the energy of activation to the levels of the nativeenzyme ... particularly attempted to investigate the functional importance of the Gly pair, located in the vicinity of the active site of the cold adapted enzyme and to study itspotential role in the establishment...
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Tài liệu Báo cáo Y học: Dissecting the effect of trifluoroethanol on ribonuclease A Subtle structural changes detected by nonspecific proteases ppt
... the content of secondary structure only after the disruption of the native tertiary structure of RNase A(Figs 2–4). Interestingly, the preservation of the tertiarystructure coincides with the ... hydro-chloride (GdnHCl), urea or elevated temperatures, theydestroy the tertiary structure of proteins which results in the loss of enzymatic activity. Regarding the secondary struc-ture of ... significantchanges of the spectroscopic properties of the enzyme couldbe detected. Therefore, the decrease of the proteolyticsusceptibility has to be attributed to a decreased (local)flexibility of the RNase...
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Báo cáo Y học: Probing the role of glutamic acid 139 of Anabaena ferredoxin-NADP+ reductase in the interaction with substrates pptx
... when studying the catalyticefficiency for these mutants in the diaphorase reaction, all of them yield values very close to those of the wild-typeenzyme at the different ionic strengths assayed (within ... FNR the side-chain of E139 might influence the properties of the flavin, assuming some of the functionscarried out by E301 in the wild-type enzyme [22]. In thiscontext, a special reactivity of the ... inother systems [35]. Therefore, it is not unexpected that the surface potential change of one of the partners might alsoproduce a different coupling of the redox cofactors involvedin the...
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Báo cáo Y học: Beyond the ABCs of CKC and SCC Do centromeres orchestrate sister chromatid cohesion or vice versa? potx
... complement of chromosomes. The fidelity of chromosome transmission is enhanced notonly by the geometry of stable centromere–MT interac-tions, but also by the action of a centromere-basedregulatory system ... way, the critical connections that hold sisterstogether from S phase through early mitosis are literally cutby Ômolecular scissorsÕ in the form of Esp1/separase at the onset of anaphase. The ... redundancy between these two complexes, they arelikely to play distinct roles in meiosis. The most fascinatingproperty of Rec8 is its persistence at sister centromeres untilanaphase of meiosis...
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Báo cáo khoa học: "Predicting the yield of Douglas fir from site factors on better quality sites in Scotland" pot
... n3ha-1yr-1 for the typical site. The 95% Cl for the mean GYCfor the site ranged from ±0.7 for the typicalsite to ±2.4 m3ha-1yr-1 for the high yieldingsite. The range ... the sum of the angles to the horizon at the 8 cardinal points of the com-pass) was the single most significant factor affecting productivity, explaining 32-69% of the ... employs some part of all the variables. The principal components obtained fromanalysis were then correlated with GYC. The variables having the greatest effect onGYC were then...
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Báo cáo y học: "Evaluating the Safety of Intranasal Steroids in the Treatment of Allergic Rhinitis" docx
... for the clinician to be comfortable with the side-effect profile and be able to discuss potential safety concerns regarding these therapies.Among the safety concerns with the use of INCs are the ... allergies are ‘ the most commonchronic condition in Canadians 12 years of age andolder.’’1In one study, 42% of children were diagnosedwith AR by the age of 6 years. The prevalence of AR hasincreased ... for the clinician to be comfortablewith the- side effect profile and be able to discuss potentialsafety concerns regarding these therapies. Among the safety concerns with the use of INCs are the...
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Báo cáo y học: "Dissecting the determinants of depressive disorders outcome: an in depth analysis of two clinical cases" pot
... 1Institute of Psychiatry, University of Bologna, Italy, 2Department of Psychology, Catholic University, Milan, Italy and 3Department of Psychiatry, San Raffaele Scientific Institute, Milan, ItalyEmail: ... bipolardisorder of Mr. A daughter strengthen the genetic hypoth-esis. On the contrary, only Mrs. B mother aunt wasaffected by depression and anxiety, pharmacologicallytreated. Therefore, the genetic ... loss anxiety and it needs earlydefenses [64].We can hypothesize that the maturity of Mr. A defenseshas a protective function, while the immaturity of Mrs. Bdefenses could be a further factor...
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Từ khóa: Nghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngChuong 2 nhận dạng rui roKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Nguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015QUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ