Báo cáo y học: "Enhanced reactivity to pain in patients with rheumatoid arthritis" ppsx

... Proinflammatory cytokines mediating burn-injury pain. Pain 2008, 135:98-107.54. Geiss A, Varadi E, Steinbach K, Bauer HW, Anton F: Psychoneu-roimmunological correlates of persisting sciatic pain in patients ... multipletypes of stressors on the physiology and symptomatology of patients with RA. Collectively, laboratory research has docu-mented a maladaptively pro-inflammatory response to stressamong RA patients, ... subscalesof bodily pain, energy/fatigue, and physical functioning. Withinthe RA group, TNF-α levels were unrelated to bodily pain orphysical functioning but showed a tendency to relate to lowerlevels...

Báo cáo y học: "Increased plasma homocysteine levels in patients with multiple sclerosis and depression" ppsx

... issuesjointly; that is, to investigate plasma homocysteine levels in patients with MS and depression.Accordingly, the present study was designed in order to assess Hcy plasma levels in MS patients ... Depression Inventory; EDSS, Extended Disability Status Scale; Hcy, plasma homocysteine; RR-MS, relapsing/remitting MS.Correlation graph between plasma homocysteine (Hcy) and Beck Depression Inventory ... Gaubatz J, Yang F, Durante W,Chan L, Schafer AI, Pownall HJ, Yang X, Wang H: Hyperhomo-cysteinemia decreases circulating high-density lipoproteinby inhibiting apolipoprotein A-I protein synthesis...

Báo cáo y học: "Elevated matrix metalloproteinase-9 in patients with systemic sclerosi" doc

... YG, Christen WG, Foster SC: Correlation of metal-loproteinase-2 and -9 with proinflammatory cytokines inter-leukin-1β, interleukin-12 and the interleukin-1 receptorantagonist in patients with ... inflammation,resulting in fibrosis. MMP-9 can trigger inflammationdirectly, by tissue destruction, or indirectly, by generation ofan inflammatory signal or recruitment of inflammatory cells[32]. Infiltration ... 92-kD gelatinase (type V collagenase) by rheumatoid syno-vial fibroblasts and its induction in normal human fibroblastsby inflammatory cytokines. J Clin Invest 1991, 88:1656-1662....

Báo cáo y học: "Altered dendritic cell distribution in patients with common variable immunodeficiency" pot

... lymphocytes of patients with com-mon variable immunodeficiency (CVI) produce reduced levelsof interleukin-4, interleukin-2 and interferon-gamma, but pro-liferate normally upon activation by ... beenreported to be normal in CVID [7,8], their involvement in theorigin of some CVID cannot be ruled out, as these cells areknown to interact directly with B cells, to present antigen to Tcells, and to ... (DCs) in the generation of immunoglobulin-secreting plasma cells. In thework reported herein, we analyzed the frequency of peripheralblood plasmacytoid DCs (pDCs) and myeloid DCs (mDCs) in acohort...

Báo cáo y học: "Atherosclerotic disease is increased in recent-onset rheumatoid arthritis: a critical role for inflammation" ppsx

... purposes) in decision-making regarding preventive measures includingstatin therapy [29], although further studies are needed to define whether this strategy is effective. In addition to monitor-ing ... related to inflammatory factors associated with RA. To investigate the presence of subclinical atherosclerosis in theearly stages of RA, we measured the cIMT in RA patients with symptom duration <12 ... USA).ResultsClinical featuresForty patients presenting with definite RA within 12 months ofsymptom onset were studied (Table 1). Three of these patients had previous CV events, including one male with...

Báo cáo y học: " Assessment of effectiveness measures in patients with schizophrenia initiated on risperidone longacting therapy: the SOURCE study results" ppt

... although theincidence of extrapyramidal AEs may vary among theatypical antipsychotics [13]. Atypical long-acting antipsy-chotic therapy, a relatively new treatment modality in man y sys tems of ... Martin SD, Medori R, Parellada E, StoRMiStudy Group: Efficacy and safety of direct transition to risperidone long-acting injectable in patients treated with various antipsychotic therapies.Int ... Br JPsychiatry Suppl 1992, 18:133-139.29. Burton SC: Strategies for improving adherence to second-generationantipsychotics in patients with schizophrenia by increasing ease of use.J Psychiatr...

Báo cáo y học: " Adjunctive long-acting risperidone in patients with bipolar disorder who relapse frequently and have active mood symptoms" doc

... requiring psychiatric intervention in the pre-vious 12 months [15]. In the or iginal study, subjects with any degree of mood symptom severity wereincluded. T he current analysis focused only on ... dis-ease characteristics, symptomatology, as well as thescales used to measure symptoms. While these data maybe hypothesi s-generating, the timing of improvement ofsymptom domains among these different ... resulted in clini-cal and symptom i mprovement within 4 weeks of treat-ment initiation with significant increases in remissionrates and patient functioning. RLAI also was found to beeffective in...

Báo cáo y học: " Prevalence of metabolic syndrome in patients with schizophrenia, and metabolic changes after 3 months of treatment with antipsychotics results from a German observational study" doc

... possibly reflec tsthat changes in metabolic parameters may occur in patients treated with any antipsychotic medication,though these may differ in grade and type according to Table 8 Laboratory test: ... thatchanges in metabolic parameters in patients treated with antipsychotics may, in part, be genetically determined[17].MetS is characterized by the coincidence of hyperten-sion, abdominal ob esity, ... abnormalresponses to insulin and diabetes-like glucose tolerancecurves [8,9] were observed in psychiatric patients. Pla-nansky and Heilizer [10] reported weight gain already in 1959 in patients treated with...

Báo cáo y học: " Immune response to allergens in sheep sensitized to house dust mite" potx

... for histological staining and immunochemistry.Eosinophil counts were determined in paraffin sectionsstained with Giemsa stain (Sigma). Mast cells weredetected in paraffin sections by immunochemical ... Briefly, PFA-fixed tissue sections wereincubated with 10% FBS in PBS to block non-specificbinding sites, followed by incubation with anti-ovinetryptase Ab (1:250 in PBS), then washed and incubated with ... immunochemical staining[23] using a polyclonal rat anti-ovine tryptase antibody,kindly provided by Prof Hugh Miller (University of Edin-burgh, UK); all sheep dermal and lung mast cells are tryp-tase-positive...

Báo cáo y học: "Rhinorrhea, cough and fatigue in patients taking sitagliptin" docx

... week Yes Yes Yes Yes 1 week 33% INS+ICS 0% 6 Yes Yes Yes 2 weeks Yes Yes Yes Yes 1 week 31% n.d. n.d. 7 Yes nil nil n.d. Yes Yes Yes Yes 1 week 17% n.d. n.d. 8 Yes Yes No Rx 2 weeks nil Yes ... N-terminal Tyr-Pro dipeptide fromNPY1-36 to generate NPY3-36 [37]. NPY3-36 binds to Y2 receptors that have relative antagonist properties to Y1 receptor activation. Y2 inhibitory autoreceptors ... n.d. Yes Yes Yes Yes 1 week 49% Positive 19% 3 Yes Yes Yes 7 weeks Yes Yes Yes Yes n.d. Restriction Positive n.d. 4 Yes nil nil 8 weeks Yes Yes Yes Yes 1 week n.d. Positive 11% 5 Yes Yes...

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