Báo cáo y học: "Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral disc" ppsx

... Kizawa H, Kou I, Iida A, Sudo A, Miyamoto Y, Fukuda A, Mabuchi A, Kotani A, Kawakami A, Yamamoto S, Uchida A, Nakamura K,Notoya K, Nakamura Y, Ikegawa S: An aspartic acid repeat poly-morphism ... analysis in disc as wasreported by Kizawa et al. [4] in cartilage. Another shortcoming is that we were not able to carry out a complete analysis of the localization of asporin in the aging/degenerating ... localization patterns of asporin within the human and sand rat intervertebral disc, and to assess asporin expres-sion in the human disc in vivo and in vitro.Materials and methodsClinical study populationExperimental...

Báo cáo y học: "Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis" ppt

... specifically control the PGE2 synthesis asso-ciated with inflammation in patients with OA and otherinflammatory diseases.ConclusionmPGES-1 was upregulated by proinflammatory cytokines in OA chondrocytes ... 485 ATG CAG CCT GCT TCT GCA AACCT TAC TCC AGA TCT GGC AT 30COX-1 401 CTT TCT CCA ACG TGA GCT ATTGTG CAT CAA CAC AGG CGC CTC TTC32COX-2 1157 AGA CAG ATC ATA AGC GAG GGC CACT TGC ATT GAT GGT ... was reported thatcartilage is the main target of cytokines such as IL-1β andTNF-α in OA, and it seems that activated chondrocytesmight be a major source of various inflammatory mediatorsassociated...

Báo cáo y học: "Deficiency of functional mannose-binding lectin is not associated with infections in patients with systemic lupus erythematosu" pptx

... to mannan (data not shown).Assessment of MBL pathway activationMBL pathway activation was assessed by an enzyme-linkedimmunosorbent assay technique that measures the completeMBL pathway activity ... pathway in this assay, an antibodyagainst C1q is added to the reaction mixture [23]. Functionalactivity of the MBL pathway was expressed as percentage of a standard consisting of pooled human ... Paarde-kooper J, Hack CE: Application of a monoclonal antibodyagainst a neoepitope on activated C4 in an ELISA for the quan-tification of complement activation via the classical pathway. JImmunol...

Báo cáo y học: "Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis" ppsx

... Furukawa H, Yoshino S, Yukioka M, Tohma S, Matsubara T,Wakitani S, Teshima R, Nishioka Y, Sekine A, Iida A, Takahashi A, Tsunoda T, Nakamura Y, Yamamoto K: Functional haplotypes ofArthritis Research ... 5PADI4, encoding citrullinating enzyme peptidylarginine deimi-nase 4, are associated with rheumatoid arthritis. Nat Genet2003, 34:395-402.8. Nakashima K, Hagiwara T, Yamada M: Nuclear localization ... of rheumatoid arthritis patients [abstract].Arthritis Res Ther 2003, 5(Suppl 1):S2.7. Suzuki A, Yamada R, Chang X, Tokuhiro S, Sawada T, Suzuki M,Nagasaki M, Nakayama-Hamada M, Kawaida R, Ono...

Báo cáo y học: "Association of ENPP1 gene polymorphisms with hand osteoarthritis in a Chuvasha population" doc

... advanced OA. In contrast to general-ized arterial calcification of infancy, in which hydroxyapatitecrystals are formed, calcium pyrophosphate dihydrate crystaldeposition is observed in these patients ... handOA in a large sample of Caucasian nuclear families. Wefocused our attention on a relatively isolated population in southern Russia, the Chuvashians. They live in small villages in the Chuvasha ... properly cited.AbstractPeriarticular calcification is a common attendant symptom ofgeneralized arterial calcification of infancy, a rare Mendeliandisorder caused by mutations of the gene coding...

Báo cáo y học: "Vitamin D receptor gene polymorphisms and susceptibility of hand osteoarthritis in Finnish wome" pdf

... thus the recall bias may affect the accuracy of informationgathered. Finally, vitamin D intake was not assessed in ourpopulation.Despite these limitations, the present findings are not antici-pated ... she was classified as having finger OA.Symmetrical OA was defined as a subcategory of OA in at least two symmetrical pairs of the joints (if two joints of the hand are affected, the same joints ... VDR baT haplotype has been related to enhancedabnormality in the calcium regulation of the parathyroid hor-mone secretion from adenomatous parathyroid cells of primary human parathyroid tumor...

Báo cáo y học: "FusionSeq: a modular framework for finding gene fusions by analyzing paired-end RNA-sequencing data" pdf

... 2005,310:644-648.24. Soda M, Choi YL, Enomoto M, Takada S, Yamashita Y, Ishikawa S, Fujiwara S,Watanabe H, Kurashina K, Hatanaka H, Bando M, Ohno S, Ishikawa Y, Aburatani H, Niki T, Sohara Y, Sugiyama Y, Mano H: ... validation of the fusion candidate. All validated fusions in this data sethave breakpoints lying at the exon boundary. Thismight indicate that, in case of genomic rearrang ement, the splicing ... annotation sets, expressionvalues, and so on.Software and data availabilityFusionSeq is available for download at [34]. Data setsused in this study are available via dbGaP [55] (studyaccession...

Báo cáo y học: "ExpressionPlot: a web-based framework for analysis of RNA-Seq and microarray gene expression data" doc

... AccessExpressionPlot: a web-based framework foranalysis of RNA-Seq and microarray gene expression dataBrad A Friedman1,2,3*and Tom Maniatis4AbstractRNA-Seq and microarray platforms have ... looking at the distribution of the wholeset, the event_heatmap tool visualizes the individual levels or fold-change of all the genes in the set as a heatmap (Figure 6c).Administrative tasksExpressionPlot ... 2way plot and table_browser. (a) 2way plot of human tissue panel RNA-Seq data [1] showingbrain gene expression on the y- axis and average expression in all other tissues (pooled) on the x-axis....

Báo cáo y học: " SpeCond: a method to detect condition-specific gene expressio" doc

... National Academy of Sciences of the United States of America 2004, 101:6062–7. 15. Ihaka R, Gentleman R: R: A Language for Data Analysis and Graphics. Journal of Computational and Graphical Statistics ... performance against alternative approaches. In all cases, SpeCond displayed higher sensitivity and a lower false discovery rate. Importantly, the SpeCond package is not a black box; the user is encouraged ... Foundation SymAtlas dataset [14], and identify specifically expressed genes from 32 human tissues samples. The method is freely available as an R package within the Bioconductor software project...

Báo cáo y học: "Hypoalbuminaemia – A Marker of Cardiovascular Disease in Patients with Chronic Kidney Disease Stages II - IV"

... between hypoalbu-minemia and CVD is the reflection of inflammation induced malnutrition. The underlying mechanism be-hind this includes appetite suppression and increased catabolism by inflammatory ... hypoalbuminaemia is an independent predictor of CVD in early CKD stages; b) hypoalbu-minaemia may be used to identify the population at higher risk for CVD. Key words: Hypoalbuminaemia, cardiovascular ... (HTN), diabetes (DM), Dyslipidemia (DLP) and advanced age. Of late, novel risk factors like malnutrition and inflammatory state have been implicated in maintenance dialysis patients (CKD stage...

Xem thêm

Từ khóa: Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018 Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thống Báo cáo quy trình mua hàng CT CP Công Nghệ NPV Nghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoại Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit ĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN Phối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọ Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ long Phát hiện xâm nhập dựa trên thuật toán k means Nghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúng Nghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000 Thơ nôm tứ tuyệt trào phúng hồ xuân hương Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2 Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vật Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật Trách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘI HIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀM