Báo cáo y học: "Regulatory T cells in systemic lupus erythematosus: past, present and future" pot

Báo cáo y học: "Regulatory T cells in systemic lupus erythematosus: past, present and future" pot

Báo cáo y học: "Regulatory T cells in systemic lupus erythematosus: past, present and future" pot

... disease activity, and the suppressive function of these cells was intact in cultures without antigen-presenting cells. The functional activity of both patient and healthy control Tregs, however, ... from becoming Th17 proinflammatory effector cells. Depletion of Review Regulatory T cells in systemic lupus erythematosus: past, present and future David A Horwitz Divi...
Ngày tải lên : 09/08/2014, 13:22
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Báo cáo y học: "Targeting B cells in systemic lupus erythematosus: not just déjà vu all over again" pdf

Báo cáo y học: "Targeting B cells in systemic lupus erythematosus: not just déjà vu all over again" pdf

... toxicities have emerged. One trivial possibility is that the binding of CD22 changes little in the organism, and thus the current randomized controlled trial may fail to find evidence for therapeutic ... even the fall in B cells in peripheral blood is quite modest and inconsistent (Figure 5 in [1]), there is at present no obvious way to follow patients for physiological effect...
Ngày tải lên : 09/08/2014, 08:22
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Báo cáo y học: "egulatory T cells in rheumatoid arthritis" ppsx

Báo cáo y học: "egulatory T cells in rheumatoid arthritis" ppsx

... healthy individuals, where they retain their capacity to initiate autoimmune inflammation [2], negative selection in the thymus is not sufficient to prevent the activation of self-reactive T cells ... occurred in the culture of PBMC derived from anti-TNF-treated patients with RA that were depleted of Tregs [38]. Together, these data might underline the potential role of cytokines in...
Ngày tải lên : 09/08/2014, 06:22
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Báo cáo y học: "Is closer linkage between systemic lupus erythematosus and anti-double-stranded DNA antibodies a desirable and attainable goal" ppsx

Báo cáo y học: "Is closer linkage between systemic lupus erythematosus and anti-double-stranded DNA antibodies a desirable and attainable goal" ppsx

... anti-dsDNA antibodies are pathophysio- logically involved in other clinical manifestations. Recent findings that intrathecal binding of anti-dsDNA antibodies to the NR2 glutamate receptor induces ... clinically relevant antibodies occurs. If anti-DNA antibody pathogenicity is determined by the interaction between antibody and tissue-specific antigens, the selection principle and/ or the...
Ngày tải lên : 09/08/2014, 06:22
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Báo cáo y học: "Replication of recently identified systemic lupus erythematosus genetic associations: a case–control study" pps

Báo cáo y học: "Replication of recently identified systemic lupus erythematosus genetic associations: a case–control study" pps

... significance. Tyk2 is a Janus-family tyrosine kinase that is bound to cytokine receptors and becomes activated after ligand binding. Defi- ciency of TYK2 leads to defects of multiple cytokine pathways, including ... effect in women and men. Competing interests The authors declare that they have no competing interests. Authors' contributions MS-G participated in design of the stud...
Ngày tải lên : 09/08/2014, 14:20
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Báo cáo y học: "TH-17 cells in rheumatoid arthritis" pdf

Báo cáo y học: "TH-17 cells in rheumatoid arthritis" pdf

... ± 7.5 years), of whom there were three taking methotrexate alone, two taking methotrexate plus an anti-TNF, one taking methotrexate and leflunomide, two taking methotrexate and abatacept and one ... between that study and other studies concerning IL-17 and TH-17 cells (including the work presented here) is not clear, although it is possible that differences in patient selection...
Ngày tải lên : 09/08/2014, 10:23
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Báo cáo y học: "Mesenchymal stem cells in arthritic disease" pot

Báo cáo y học: "Mesenchymal stem cells in arthritic disease" pot

... proliferative ability in an uncommitted state while retaining the potential to differentiate along various lineages of mesenchymal origin, including chondrocyte, osteoblast, and adipocyte lineages, in response ... immunosuppressive and anti-inflammatory functions that have been demonstrated both in vitro and in vivo. Due to the scarcity of MSCs, especially the apparent decrease...
Ngày tải lên : 09/08/2014, 13:22
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Báo cáo y học: "Line bisection performance in patients with generalized anxiety disorder and treatment-resistant depressionLine bisection performance in patients with generalized anxiety disorder and treatment-resistant depression"

Báo cáo y học: "Line bisection performance in patients with generalized anxiety disorder and treatment-resistant depressionLine bisection performance in patients with generalized anxiety disorder and treatment-resistant depression"

... on the other. Bearing that GAD and TRD patients often present negative emotions in mind, we have hy- pothesized that these subjects would bisect lines fur- ther leftward than the healthy volunteers ... bisection error to the left of the true center has been interpreted as a relative right hemisphere activation, which might relate to the subject’s emotional state. Considering that pat...
Ngày tải lên : 26/10/2012, 08:57
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Báo cáo y học: "Skin prick testing in patients using beta-blockers: a retrospective analysis" pot

Báo cáo y học: "Skin prick testing in patients using beta-blockers: a retrospective analysis" pot

... patient was taking cetirizine and another was taking amitriptyline at the time of skin testing. These medications may have blunted the skin test response. Other common concomi- tant medications ... important, we argue that with allergy skin prick testing and intradermal testing with insect venoms and penicillin, the risk of anaphylaxis is so low that testing can be completed safely on m...
Ngày tải lên : 08/08/2014, 21:20
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Báo cáo y học: "Estimated intelligence quotient in anorexia nervosa: a systematic review and meta-analysis of the literature" pot

Báo cáo y học: "Estimated intelligence quotient in anorexia nervosa: a systematic review and meta-analysis of the literature" pot

... population. We based this hypothesis on thefactthatitwasshownthatIQpredictstermination from treatment; that is, patients with a higher IQ are more likely to remain in psychological treatment [14]. Methods Search ... contributed to drafting the manuscript. DS contributed to the design of the study, performed the statistical analyses, drafted the results section and critically reviewed the...
Ngày tải lên : 09/08/2014, 01:21
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