Báo cáo y học: "Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity" ppt
Tài liệu Báo cáo Y học: Granule-bound starch synthase I A major enzyme involved in the biogenesis of B-crystallites in starch granules ppt
... measuresignificant rates of amylose synthesis and we can onlystate that the latter certainly does not exceed the rate of amylopectin synthesis. The increase in crystallinity wit-nessed during these first 12 ... displays the length and position of the six introns within the GBSSIsequence compared with those of rice and potato. The number and position of the introns are unrelated to those present in vascular ... issynthesized in vivo when the rate of amylopectin synthesisbecomes minimal. At these moments the rates of amylopec-tin synthesis are only 5% of their maximal values. In fact thislow rate of...
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Báo cáo y học: "Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity" ppt
... correlation between the proportion of total NKT cells and disease activity or drug therapy in our lupus patients, which suggests that the reduction in NKT cells in these patients does not arise ... cytokinesthat are secreted by the NKT cells in the different lupus mousemodels, with interleukin-4-secreting NKT cells inhibiting lupus and interferon-γ-secreting NKT cells exacerbating lupus [53,54,56,57]. ... herita-ble trait. These findings raise the possibility that one of the explanations for the clustering of multiple autoimmune disor-ders within the families of lupus patients is the presence of genetic...
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Báo cáo Y học: Guanosine diphosphate-4-keto-6-deoxy-D-mannose reductase in the pathway for the synthesis of GDP-6-deoxy-D-talose in Actinobacillus actinomycetemcomitans potx
... respectively) to the proteins enco-ded by ORFs in the clusters responsible for synthesizing the SPAs in other serotypes of A. actinomycetemcomitans. The biosynthetic pathway for GDP-6-deoxy-D-talose,Fig. ... regardless of the addition of the proteins. The peak that appeared at 24.0 min was in agreement with that of authentic NADP+. The reason why the NADP+peak appeared in the gmd gene productreaction ... 48.0% [43]. The GC content of the region essential for the biosynthesis of SPA in the otherserotype strains (b–e) of A. actinomycetemcomitans is alsolower than the average GC content of these genes...
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Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx
... isolated from thermophilic bacteria are usuallystable to heat and chemical denaturants, indicating that theymust have most of the determinants of protein stability.Initial clues to the relationship ... character of HT c-552 may depend on a few strong noncovalentinteractions. We further found that the increase in the stability of the quintuple mutant is almost the same as the sum of the three individual ... other in a proteinmolecule, and subtle changes in them can affect the overallstability. Thus, it is usually difficult to identify the exactfactors that contribute to the enhanced stability of the proteins...
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Báo cáo Y học: Mistletoe viscotoxins increase natural killer cell-mediated cytotoxicity pptx
... cytolyticactivity against the activating target, nor does it weaken the latter in such a way as to increase their lysis in the assay.Besides the lack of viscotoxin toxicity for the various targets cells ... bioactive in NK lysis are VTA1-3On the one hand, proteins were unexpected for the unusualthermostability and protease-insensitivity of the bioactiveextract, but, on the other hand, they could ... related to the family of thionins [46] and notoriously resistant to protein-denaturing agents [45,47]. Table 1 shows that the startingbioactivity of the Va extract has such characteristics. Otherworkers...
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Báo cáo y học: "THR0921, a novel peroxisome proliferator-activated receptor gamma agonist, reduces the severity of collagen-induced arthritis" pps
... As the involvement of each of these cytokines in the pathogenesis of arthritis is wellFigure 5Steady state mRNA levels of the inflammatory cytokines IL-1β, mono-cyte chemotactic protein (MCP)-1, ... this may bea primary mechanism by which THR0921 provides clinicalbenefit. The effect of THR0921 and other PPARγ ligands maybe due to their ability to inhibit the activity of key transcriptionfactors ... concentrations shown. After incubation, cells were stained with the tartrate-resistant acid phosphatase (TRAP) staining kit and enumerated under 40× magnification. The mean ± standard error of the...
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Báo cáo y học: " High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease." docx
... construct on the function of HMGB1, the importantissue is not the contribution of any possible ‘contamination’ of purified HMGB1 in in vitro experiments but rather the actualfunction of the ... Down-regulation of the aberrantexpression of the inflammation mediator high mobility groupbox chromosomal protein 1 in muscle tissue of patients with polymyositis and dermatomyositis treated with corticos-teroids. ... to alert the immune system to tissuedamage and to trigger an immediate response. A key facet of the biology of alarmins is therefore their translocation from the inside to the outside of the cell...
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Báo cáo y học: "Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis" ppsx
... collected from patients with septicemic melio-idosis and patients with sepsis and isolation of other organ-isms in the training and the two test sets concerning the totalleukocyte, platelet, ... constituting an excellent tool in the dis-covery phase, are currently inadequate for routine testing.Indeed, the data that are generated are not quantitative and are therefore susceptible to batch-to-batch ... sample are indicated by a spot, with the intensity of the spot representing the proportion of significantly differentially expressed transcripts for each one of the transcriptional modules. The...
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Báo cáo y học: " Protein kinase A-dependent Neuronal Nitric Oxide Synthase Activation Mediates the Enhancement of Baroreflex Response by Adrenomedullin in the Nucleus Tractus Solitarii of Rats" pps
... conceived of the study, designed and coordinated the experiments, and drafted the manuscript. All authors read and approved the final manuscript.Competing interests The authors declare that they have ... neuron. The enzyme activity of nNOS has been demonstrated tobe intimately associated with the state of phosphorylationat the amino acid residues Ser847 and Ser1416 [19]. Forinstance, phosphorylation ... in BRR enhancement that is mediated by a PKA-dependent mechanism in theNTS[12].Inthepresentstudy, the effect of ADM on baroreflex was further sug-gested to involve the activation of nNOS in...
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Báo cáo y học: " Non infective severe aortic paravalvular leakage 7 years after surgery: the role of suture technique" pot
... a partial prosthesis detachment at the level of the non coronary aortic sinus, due to the semicontinuous suture breaking (Figure 2). The othertwo sutures of the left and right coronary sinuses ... the aortic annulus and sew-ing ring of the artificial valve prior to lower the prosthe-sis. Then a gentle alternate traction on the threesemicontinuous sutures, usually with the help of asurgical ... or involving the anterior leaflet of mitral valve; the supraannularposition permits a prosthesis oversizing to reduce the risk of patient mismatch, without increasing the risk of PVL.At present...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVchuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDENghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Kiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)MÔN TRUYỀN THÔNG MARKETING TÍCH HỢPTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ