0
  1. Trang chủ >
  2. Luận Văn - Báo Cáo >
  3. Báo cáo khoa học >

Báo cáo y học: "Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis" pdf

Báo cáo y học:

Báo cáo y học: "Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis" pdf

... 4Research articleNovel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritisPei Jin1, Juan Zhang1, Percy F Sumariwalla2, ... VEGF receptor type 1, VEGF receptor type 2, VEGF receptor type 3, angiopoietin receptor Tie1, Met (receptor for hepatocyte growth factor), colony-stimulatingfactor 1 receptor, platelet -derived ... destruction.Conclusion The present study shows that unique ASV derived from receptors that play key roles in angiogenesis – namely,VEGF receptor type 1 and, for the first time, Tie1 – can markedlyreduce...
  • 16
  • 481
  • 0
Báo cáo y học:

Báo cáo y học: "Novel self-epitopes derived from aggrecan, fibrillin, and matri" ppt

... iscrucial for the understanding of disease pathogenesis andadditionally may provide targets for antigen-specific immunetherapy. In this study, we tested 9 self-peptides derived from joint-related ... IFN-γ.Cytokine analysis by lymphocyte intracellular staining and flow cytometryT-cell cultures were performed as described above for 72hours with 4 × 105 cells in 200 μl per well using PBMC from 14 ... their parents. The local medical ethics reviewboard approved the study.Peptide selection and synthesis The joint-related self-epitopes were selected on the basis of the molecular mimicry computer...
  • 10
  • 335
  • 0
Tài liệu Báo cáo Y học: Trehalose-based oligosaccharides isolated from the cytoplasm of Mycobacterium smegmatis Relation to trehalose-based oligosaccharides attached to lipid docx

Tài liệu Báo cáo Y học: Trehalose-based oligosaccharides isolated from the cytoplasm of Mycobacterium smegmatis Relation to trehalose-based oligosaccharides attached to lipid docx

... 269) 3143 The origin of these cytosolic oligosaccharides is notknown. They could be synthesized in the cytosol byglycosyltransferases which add glucosyl or galactosyl resi-dues to the free ... any of the reactions involved in their biosynthesis represent excellent potential target sites for chemotherapeutic intervention intuberculosis. However, in mycobacteria there may be asmany ... different pathways for the formation oftrehalose. The well-established pathway involves forma-tion of trehalose 6-phosphate by transfer of glucose from UDP-glucose to glucose 6-phosphate by the trehalosephosphate...
  • 8
  • 403
  • 0
Báo cáo Y học: Two GPX-like proteins from Lycopersicon esculentum and Helianthus annuus are antioxidant enzymes with phospholipid hydroperoxide glutathione peroxidase and thioredoxin peroxidase activities pptx

Báo cáo Y học: Two GPX-like proteins from Lycopersicon esculentum and Helianthus annuus are antioxidant enzymes with phospholipid hydroperoxide glutathione peroxidase and thioredoxin peroxidase activities pptx

... of the opal codonUGA used for insertion of a selenocysteine in mammalGPXs. The selenocysteine residue is important for the catalytic activity of GPX as replacement of selenocysteine bycysteine ... phospholipidhydroperoxides and a weaker affinity towards t-butylhydroperoxide, as indicated by their respective apparentKmvalues. There was no detectable activity with hydrogenperoxide.Considering the ... GPX4-like GPX. However, these in vitro activitiesremain low. This can be explained by the lack of the rareselenocysteine residue replaced by a cysteine in the catalyticsite of plant GPXs [13]....
  • 7
  • 362
  • 0
Báo cáo Y học: Thermal stability of peroxidase from the african oil palm tree Elaeis guineensis pdf

Báo cáo Y học: Thermal stability of peroxidase from the african oil palm tree Elaeis guineensis pdf

... followdenaturation (y) prior to the minimization procedure,according to the expression:FU¼ y À y NÞ= y y NÞð6Þwhere y N¼ a1+ a2T and y U¼ b1+ b2T represents the mean values of the y characteristic ... experimental data, there are as yet no publications inwhich DSC data have been interpreted through the use of the whole Lumry–Eyring kinetic model [18]. Therefore, toanalyse the irreversible thermal denaturation ... ÀXni ¼1 y y calciÞ2Xni ¼1 y y miÞ2sð2Þwhere y iand y calci are, respectively, the experimental andcalculated values of Cexp; y miis the mean of the experimentalvalues...
  • 7
  • 615
  • 0
Báo cáo y học:

Báo cáo y học: "ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis" pdf

... elegans. They formpart of subfamily B (adamalysin subfamily), family M12, in clanMA of the metallopeptidases, as defined in the MEROPSdatabase [5,6] and are structurally and evolutionarily relatedto ... cleave the growth factor,suggesting that the inhibitory effect is brought about bysequestering VEGF from its cell receptor [41]. By analogy to the thrombospondins, the angioinhibitory activity might ... theseinteractions [83,84]. These processing events also alter the activities of these proteins; for example, they reduce the angioinibitory capacity of ADAMTS-1 and alter the activity ofADAMTS-4 against...
  • 10
  • 312
  • 0
Báo cáo y học:

Báo cáo y học: "Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis" pps

... subject totake the tablets during the 30 day supplement period. The subjects were asked to return the bottle for a tablet count at the end of the 30 day treatment. To test the efficacy of the vita-min ... through the same2 day testing procedure described above at the end of the 30day supplementation period.Laboratory analysesBlood hematology and chemistry analyses and urinalysis wereperformed ... concentration was assayed by the tyrosine decarboxylase enzymatic procedure of Camp etal. [20] with a modification of the extraction procedure for plasma and erythrocytes. The modification is...
  • 8
  • 415
  • 0
Báo cáo y học:

Báo cáo y học: "tatin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis" pptx

... geranylgeraniol reversed the response, confirming a role for inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase and geranylgeranylation.Likewise, inhibition by NG-monomethyl-L-arginine ... geranylgeranyl pyro-phosphate and geranylgeraniol, but not farnesylpyrophosphate or squalene, reverse statin-mediated effects. The role of geranylgeranylation in CD59 expression was there-fore ... flow-cytometric analysis. EAL wasinvolved in endothelial cell isolation, northern analysis andstudy design. PHM participated in the design of the study andsupervised experiments performed in the...
  • 12
  • 510
  • 0
Báo cáo y học:

Báo cáo y học: " Impact of concomitant DMARD therapy on adherence to treatment with etanercept and infliximab in rheumatoid arthritis. Results from a six-year observational study in southern Sweden" docx

... CRP levels might be a predictor for a high level of adher-ence to therapy. On the other hand, the 1-year level of adher-ence to therapy found in our study closely resembles valuesfound in randomised ... 10(page number not for citation purposes)other DMARDs, and finally a group of patients treated withTNF blockers as the only antirheumatic therapy (mono-therapy). The group 'other DMARD' ... mono-therapy, the levels of adherence to therapy at 4 years (1 year)were 18% (47%) and 53% (74%), respectively. The corre-sponding numbers for TNF blockers given in combination withother DMARDs...
  • 10
  • 502
  • 0
Báo cáo y học:

Báo cáo y học: "Low-intensity pulsed ultrasound activates the phosphatidylinositol 3 kinase/Akt pathway and stimulates the growth of chondrocytes in three-dimensional cultures: a basic science study" pot

... system by preferen-tially activating the PI3K/Akt pathway rather than the MEK/MAPK pathway.Cyclin B1 and cyclin D1Consistent with the increased chondrocyte growth, the expression of the ... significantly but only tran-siently on day 3 of culture, in comparison with the controlgroup [15]. In the current study with a 3D culture system, the number of chondrocytes doubled by the end of the ... 0517591586, 2005–2006) from the Japanese Ministry of Education, Culture, Sports, Science and Technology, and Grants of the Kenkyu-Senryaku Project (2007) from Yokoham City University.References1....
  • 11
  • 483
  • 0

Xem thêm

Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnmẫu báo cáo y học cổ truyềnbao cao y hoc colchicinphan ban luan trong bao cao y hoc co truyenbáo cáo khoa học ảnh hưởng của việc thay thế cỏ xanh trong khẩu phần bằng bã dứa ủ chua đến khả năng sản xuất của bò thịt potNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVchuyên đề điện xoay chiều theo dạngNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Nguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Chiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namMÔN TRUYỀN THÔNG MARKETING TÍCH HỢP