... analysis of Ikaros has indicated that it containsdistinct domains that are implicated in activating orrepressing transcription [4,5,19,33]. One discrete domainwithin the N-terminus contains ... that other (nonpocket) regions of CtBP will beinvolved in the interaction. In this way, it seems likely thatproteins such as Eos may be able to bind to CtBP that is already associated with another ... family protein Eos associates with C-terminal-binding protein corepressorsJose´Perdomo and Merlin CrossleyDepartment of Biochemistry, G08, University of Sydney, NSW, AustraliaEos is a zinc...