Báo cáo khoa học: " What is an acceptably smoothed fluence? Dosimetric and delivery considerations for dynamic sliding window IMRT" ppt
Báo cáo khoa học: " What is an acceptably smoothed fluence? Dosimetric and delivery considerations for dynamic sliding window IMRT" ppt
... OncologyOpen AccessResearch What is an acceptably smoothed fluence? Dosimetric and delivery considerations for dynamic sliding window IMRTNicolini Giorgia1, Fogliata Antonella1, Vanetti Eugenio1,2, ... conditions s25 and s80Figure 4DVHs of targets and organs at risk (Head and Neck case) for the two extreme smoothing conditions s25 and s80.Table 2: DVH analysis: differences between plans obtained ... by changing calculation algorithm (PBC and AAA) and dose calculation grid (2.5 mm and 5.0mm). Dose distributions were analysed in terms of DVH for the planning target volumes (PTV) and for the...
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Báo cáo khoa học: LIN54 is an essential core subunit of the DREAM / LINC complex that binds to the cdc2 promoter in a sequence-specific manner ppt
... DHCH and D Nmutants in a panel of different cell lines. Although diffi-cult to overexpress, distinct bands corresponding toLIN54 and the DHCH and DN mutants could bedetected (marked by asterisks). ... depletion ofhuman LIN9 and B-MYB [9–11]. This suggests thatthe ability to promote cell cycle progression and mito-tic entry is not an isolated function of LIN9 and B-MYB, but that it is mediated ... beenfound in plants and animals, but not in yeast. Thefounding family member TSO1 is essential for flowerdevelopment [17,18]. Mutations in TSO1 cause defectsin mitosis and cytokinesis. Interestingly,...
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Báo cáo khoa học: "What is the Minimal Set of Fragments that Achieves Maximal Parse Accuracy?" potx
... size and lexicalization, are in principle taken to form agrammar (see Bod 1993, 1998; Goodman 1998;Sima&apos ;an 1999). The set of subtrees that is used is thus very large and extremely redundant. ... structure and probability.These rules are used to create a derivation forest for a sentence (using a CKY parser), and themost probable parse is computed by sampling asufficiently large number of random ... 90.8% LP and 90.5% LR outperformthe scores of the best previously published parserby Charniak (2000) who obtains 90.1% for bothLP and LR. Moreover, our scores also outper-form the reranking...
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báo cáo khoa học: "What is the value and impact of quality and safety teams? A scoping review" potx
... evaluation and creationof a valid, useful knowledge and evidence base for qual-ity and safety. This will require improved conceptions ofthe nature of quality and safety issues, an understandingof ... understand the types ofquality and safe team initiatives, the evidence abouttheir impact, and the barriers and facilitators to estab-lishing teams and team initiatives.MethodsData sources and ... MEM, and AJFscreened search results and reviewed papers against the inclusion criteria.DEW, SES, and JMN extracted data and assessed papers for methodological and reporting quality. DEW and...
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Báo cáo khoa học: Prohibitin is expressed in pancreatic b-cells and protects against oxidative and proapoptotic effects of ethanol pdf
... 2-mercaptoethanol, 2% SDS,62.5 mm Tris ⁄ HCl, pH 6.7) at 50 °C for 30 min and rep-robed with anti-actin, anti-heat shock protein 60 or anti-his-tone H1 serum as appropriate. Quantitative image analysiswas ... FEBS 495Statistical analysisThe data were analyzed by one-way ANOVA with Tukeymultiple comparisons or Student’s t-test and are presentedas the mean ± standard error of the mean (SEM).P < ... PHB is essential for normal mitochondrial development and its deficiency in yeasts and Caenorhabditis elegans is associated with deficient mitochondrial function [44] and a reduced life span [45,46]....
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Tài liệu Báo cáo khoa học: Antimicrobial effects of H4-(86–100), histogranin and related compounds – possible involvement of DNA gyrase ppt
... attachment, capture and destruction ofinvading microorganisms. The NETs contain nuclearmaterials that include DNA and bactericidal proteins and histone-derived peptides such as buforins and pos-sibly ... finding of buforin-I inporcine, bovine and human stomach lavage fluids sup-ported the concept that such a defense mechanism alsoexists in vertebrates. In chicken, antimicrobialhistones H2A and H2B ... CB, Kim HS & Kim SC (1998) Mechanism ofaction of the antimicrobial peptide buforin II:buforin II kills microorganisms by penetrating the cellmembrane and inhibiting cellular functions....
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Tài liệu Báo cáo khoa học: The nuclear lamina Both a structural framework and a platform for genome organization pdf
... structural framework and a platform for genomeorganizationJoanna M. Bridger1, Nicole Foeger2, Ian R. Kill1 and Harald Herrmann31 Centre for Cell and Chromosome Biology, Division of Biosciences, ... [1]).Moreover, their down-regulation is associated withspecific cancers, such as lymphoma and leukaemia [2], and lung cancer [3].In contemporary metazoan cells the lamina is com-prised of fibrous polypeptides ... phylalike cnidaria or nematodes and four major forms inmammals, designated A-type (lamin A and lamin C) and B-type (lamin B1 and lamin B2), in addition to an increasing number of associated...
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Tài liệu Báo cáo khoa học: Casein kinase 2 specifically binds to and phosphorylates the carboxy termini of ENaC subunits ppt
... Amino acid analysis of phosphorylated GST-b and -c. The circles indicate positions ofmarker phospho serine, threonine and tyrosine. (B and C) Phosphorylation of wild-type and mutated b and c subunits ... serines and threonines on the Ctermini of b and c weremutatedtoalanineandexamined for phosphorylation by fraction 76. In b the majorphosphorylated residue was S631 and mutating it to alanineblocked ... b,andc)whichtransverse the membrane twice so that both the C and Ntermini are intracellular [5–8]. Cell surface expression ofENaC is determined by an interaction between the C tails ofb and...
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Báo cáo khoa học: A large complex mediated by Moc1, Moc2 and Cpc2 regulates sexual differentiation in fission yeast ppt
... H. Kato and Y. Matsuo for technicaladvices and R. Ogawa for her technical assistance.This research was supported by grant-aid from theMinistry of Education, Culture, Sports, Science and Technology ... Zn-finger-type protein is localized to the nucleus and is involved in stress resistance and sexual differentia-tion [15]. Moc4/Zfs1 contains two Zn-finger motifs, is localized to the nucleus, and is involved ... in30 lL lysis buffer (including protease inhibitor and PMSF) and 60 lLof2· Laemmli buffer (4% SDS, 20% glycerol,0.6 m b-mercaptoethanol, 8 m urea and 0.12 m Tris/HClpH 6.8) was added and vortexed....
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Báo cáo khoa học: A single intersubunit salt bridge affects oligomerization and catalytic activity in a bacterial quinone reductase pptx
... protein variants. The two double protein vari-ants give rise to bands positioned between the K109L and D137L variant. Considering that the two doubleprotein variants have an intermediate isoelectric ... bridgebetween Lys109 and Asp137 is formed across this interface. (B) Inthe K109D ⁄ D137K variant, the number of interactions is greatlyreduced and the salt bridge can no longer be formed. The figurewas ... Steady-state and rapid reaction parameters for wild-type YhdA and protein variants. Turnover measurements were carried out withNADPH and oxygen as substrates. The rate of reduction and oxidation...
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