... inhibition studiesThe nature and magnitude of the inhibition by the productgalactose 1-phosphate was determined by observing theeffect of increasing concentrations of the compound on theapparent turnover ... in lens fibre cells cause the uptake of water by osmosis, swelling of the cells, cells lysis andultimately cataracts. The condition is treated by removal of galactose and lactose from the diet.Galactokinase ... (Fig. 3) with a turnover number (kcat )of8 .7s)1,Km,gal of 970 lMand Km,ATP of 34 lM. These values are of the same order of magnitude as previously reported for theyeast [23], rat [18,19]...