Báo cáo y học: "Identification of an altered peptide ligand based on the endogenously presented, rheumatoid arthritis-associated, human cartilage glycoprotein-39(263–275) epitope: an MHC anchor variant peptide for immune modulation" pot
Báo cáo y học: "Identification of an altered peptide ligand based on the endogenously presented, rheumatoid arthritis-associated, human cartilage glycoprotein-39(263–275) epitope: an MHC anchor variant peptide for immune modulation" pot
... modification at the key MHC anchor position. The latter quality may add to improved safety of APL therapy.Ideally, the properties of an APL for immunotherapy of RAwould blend: affinity for MHC class ... substitutions mayfunction as partial TCR agonists on the one hand and preventunwanted immune reactivity on the other [32,33]. Thisapproach may thus provide an improved option for APLtherapy. The ... not shown).In conclusion, the analysis of both the hybridoma panel and the polyclonal T cell response to the 263–275 epitope has led to the identification of MHC binding and TCR contact residueswithin...
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Báo cáo y học: "Impact of drug classes and treatment availability on the rate of antiretroviral treatment change in the TREAT Asia HIV Observational Database (TAHOD" pdf
... Yuliana, Faculty of Medicine Udayana University & Sanglah Hospital, Bali, Indonesia;S Oka* and M Honda, International Medical Centre of Japan, Tokyo, Japan;JY Choi* and SH Han, Division ... Insti-tute of Allergy and Infectious Diseases (NIAID), grant no. U01-AI069907, and the Ministry of Foreign Affairs of the government of The Netherlands. The National Centre in HIV Epidemiology and ... http://www.aidsrestherapy.com/content/4/1/18Page 8 of 10(page number not for citation purposes)confirms the hypothesis that most of the switches are dueto toxicity or tolerance issues rather than related...
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Báo cáo y học: "Identification of a SmD3 epitope with a single symmetrical dimethylation of an arginine residue as a specific target of a subpopulation of anti-Sm antibodies" ppsx
... of inhibition can beexplained by the variety of different anti-Sm antibody sub-populations and by the variety of corresponding epitopes.Recently, two polyclonal antibodies (SYM10, SYM11)were ... mapping of the carboxyl-terminal extensions of SmD1 and SmD3To evaluate the effect of arginine dimethylation on the anti-genicity of SmD1 and SmD3 and to localize relevantepitopes on both polypeptides, ... specifically bind to the symmetricalform of dimethylarginine and react with a variety of otherknown autoantigens [42]. Those antibodies may shed morelight on the correlation of anti-SMP antibodies...
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Báo cáo y học: "Identification of clinical and simple laboratory variables predicting responsible gastrointestinal lesions in patients with iron deficiency anemia"
... bleeding lesion. GI evaluation can be endoscopic and radiographic. Asymptomatic colonic and gastric carcinoma may present with IDA and exclusion of these conditions is of prime concern. The upper ... [3-6, 11]. Iron deficiency anemia is considered as an alarm sign for the presence of possible GI malignancies, and inadequate evalua-tion of patients with IDA may delay the diagnosis of GI tumors ... minimally 12 and maximally 60. The patients investigated previous smoking history, coronary artery disease, diabetes mellitus and malignancy history in their family. Statistical Analysis ...
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Báo cáo y học: "Identification of Cellular Membrane Proteins Interacting with Hepatitis B Surface Antigen using Yeast Split-Ubiquitin System"
... recombination. Yeast colony PCR was done for 22 randomly picked colonies to assess the size of cDNA insert. For each colony picked, half was streaked on SD/-Trp plate and the other half inoculated ... are then cloned into the yeast cell and expressed on the cell membrane. If the prey protein interacts with the bait protein, this would bind the NubG and Cub domains together to form the ubiquitin ... co-receptor of coxsakie B virus. The significance of our findings is suggested by the identification of cellular membrane proteins interacting with other virus proteins. Further functional analysis of...
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Tài liệu Báo cáo Y học: Characterization of an omega-class glutathione S-transferase from Schistosoma mansoni with glutaredoxin-like dehydroascorbate reductase and thiol transferase activities pptx
... [38]. The same abnormality was also observedwhen the phylogenetic analysis of S. mansoni nuclearreceptors was performed [39]. The proposed explanation for this observation is that the human parasites ... strong inhibitory effect of S-hexylglutathione on the enzyme activity. The preference of SmGSTO for more hydrophobic alkyl-bound S-hexylglutathione rather than glutathione could reflect someparticular ... additional functions wereattributed to GSTs including the transport of hydrophobicligands, binding to bilirubin and carcinogens [3,4], the isomerization of maleylacetoacetate and the regulation of stress...
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Báo cáo y học: "Identification of subpopulations with characteristics of mesenchymal progenitor cells from human osteoarthritic cartilage using triple staining for cell surface markers" docx
... (re)differentiationpotential of distinct subpopulations are necessary toimprove further the functional quality of the cell populationsused for transplantation. The methods of FACS analysisand cell ... patients and analyzed the kinet-ics of cultivation and the potential for differentiation. The data analysis after sorting is exemplarily shown for onepatient in Fig. 4. The gates used for cell ... offer important approaches for quality con-trol and application of cell populations with greater purity.ConclusionIn conclusion, there is increasing evidence for cellular het-erogeneity of...
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Báo cáo y học: "Screening of an endothelial cDNA library identifies the C-terminal region of Nedd5 as a novel autoantigen in systemic lupus erythematosus with psychiatric manifestations" ppt
... analysis and the clinical associa-tions. AS participated in the analysis and interpretation of dataand in the revision of the manuscript. RR participated in the design of the study and in the revision ... screening of the library and participated in the design of the study and in the analysis of data. MS carriedout the experiments on endothelial cell line and apoptosis andparticipated in the design of ... revision of the manuscript. EPparticipated in analysis of data. GV participated in the designand revision of the study. EO conceived of the study, partici-pated in its design and coordination, and...
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Báo cáo y học: "Identification of kinectin as a novel Behçet''''s disease autoantigen" doc
... anti-kinectin antibody with different manifesta-tions or disease 'subtypes' of BD is another important project.Anti-kinectin is clearly only one of the antigen-antibody sys-tems identified ... 3'-untranslated region. (b) Autoradiography of in vitro transcription and translation products of the candidate clones BD44 and BD42 labeled by [35S]-methionine and analyzed on a 12.5% gel SDS-PAGE. ... tran-scription and translation of BD44 and BD42 clones directed the synthesis of [35S]-methionine-labeled polypeptides thatmigrated at 95 and 60 kDa, respectively, in addition to smallerpolypeptides...
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Báo cáo y học: "Identification of citrullinated α-enolase as a candidate autoantigen in rheumatoid arthritis" doc
... isdemonstrated by the uniform migration of deiminated enolaseat a pI of 5 and by the replacement of arginine by citrulline inall the peptides listed in Table 1.In our study, 15% of the control ... mainly confined to the subsynovium. (b) No staining was visible on the control. (c) Staining produced by the anti-α-enolase antibody on an adjacent section was much stronger, and included the ... that,among the numerous potential antigens generated by citrulli-nation of proteins in cells of monocytic phenotype, there wasapparent selectivity among our four screening sera for one cit-rullinated...
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnmẫu báo cáo y học cổ truyềnbao cao y hoc colchicinphan ban luan trong bao cao y hoc co truyenreceived including services rendered by employees through its own equity instruments or an amount that is based on the value of its own equity instruments such as share options or share appreciation rights1990 p 86 the difficulty or lack of difficulty a word presents may override its frequency and or range and decisions to bring forward or postpone the teaching of an item may be based on learnabilitymultilayer adsorption in binary liquid mixtures calculation of thermodynamical potential function profiles based on the lattice model f bergerstudents assessment of speaking topics and activities based on the textbook new headway pre intermediate the third editionqualitative data analysis qda process example of data reduction invivo coding based on the interview transcriptbáo cáo khoa học y họcbáo cáo y tế học đườngmẫu báo cáo y tế học đườngbáo cáo y tế học đường cuối nămbáo cáo y tế học đường năm 2012Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXChuong 2 nhận dạng rui roKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ