... be
confined to the periphery. The finding of increased areas of
punctate hyperalgesia in patients with RA after topical
application of capsaicin is in accord with increased
excitability of spinal ... role in the treatment of
chronic pain, although there have been few studies assessing
the efficacy of the technique for arthritic pain. Underlying
mechanisms of...
... [57].
Recognizing early symptoms of hepatic toxicity and dis-
continuing treatment are important in optimizing recov-
ery. Early symptoms of hepatic toxicity include apathy,
malaise, fever, diminished ... and lamotrigine. The triad of hypersensi-
tivity includes fever, rash and internal organ involvement
with onset of symptoms within 1 to 8 weeks of exposure.
The frequency...
... of leisure in maintaining or restoring psychological well-
being in the presence of arthritis pain warrants further
study.
Psychosocial approaches to managing
arthritis pain
Search strategy
The ... [16]
compared the psychosocial functioning and coping of
mothers with chronic pain (including mothers with arthritis) to
mothers without pain, with regard to their ratings of pa...
... explained in the following way. The chance of
finding a seed-match and of producing a local alignment
of significant similarity rises with the length of the frag-
ment. Longer fragments, then, ... sequences
include only a small proportion of microbes found in
nature [14]. Finally, the target genome used for detection
of fragments of interest may not be sufficiently...
... be the start of the protein
coding domain. Sequence analysis of the 3¢ end cDNA
revealed that there is a polyadenylation signal upstream of
the poly(A).
Analysis of the primary structure of
M. ... 2002
Recently, the a subunit of a G protein of the Gq family
has been immunolocalized in olfactory sensilla preparations
of the silkmoth Antherea pernyi [23]. Using...
... to the break indices. Although in-
corporation of this information reduced the num-
ber of possible parses, the processing time in-
creased because of the addition of the link nodes
in the ... number indicating its position rela-
tive to the other words in the sentence. Once
a word is entered in the network, the system
assigns all of the possible...
... fibroblast lines. YM participated in the
molecular genetic studies and analysis. EK procured the sam-
ples and helped in the analysis of data. GW participated in the
design of the study, analysis of data, ... early
bacterial infection in the joint. Somatic mutations in
mitochondrial peptides displayed by MHCs may be recognized
as non-self, furthering the destruct...
... concerning the
role of T lymphocytes, B lymphocytes, dendritic cells, and
other antigen-presenting cells (APCs) in the pathophysiology
of IIMs.
T lymphocytes
T lymphocyte function
T lymphocytes ... demonstrated the presence
of differentiated B lymphocytes in the form of CD138
+
plasma
cells predominantly in the endomysium of muscle tissue of
patients with polymyosi...
... anti-
IL-15 therapy in RA patients [29].
T helper 17 cells
There is increasing evidence that IL-17 plays a role in the
immunopathology of RA. This proinflammatory cytokine is
produced by T helper ... anti-CD20 antibody
[2], and the increased interest in the role of autoantibodies in
RA. In addition to producing antibodies, proinflammatory
cytokines and chemokines, B cells...
... Surgery appears to be preferable as a one arm of multimodality therapy in p-stage III/N2 patients with
single or 2 involved lymp h nodes. The optimal incorporation of surgery into the multimodality ... conceived of the study, and drafted the manuscript. MT participated in
the study and performed the statistical analysis. SO, YS, YN, HS, HU, and FT
participated in the...