... vol-ume delineation significantly reduced the GTV and itsexpansions, CTV and PTV, in 12 of 13 patients and increased target volumes in 1 patient, all together impact-ing the importance of accurate ... definition of target volumes with additional metabolic information, and it was more successful in discriminating betweentumor and benign connective tissue changes.The additional volume and intratumoral ... delineate target volumes separately. For each patient, target volumes (gross tumor volume [GTV], clinical target volume [CTV], and planning target volume [PTV]) were defined using the CT and PET-CT...