Báo cáo khoa học: "Job stress and job satisfaction of physicians, radiographers, nurses and physicists working in radiotherapy: a multicenter analysis by the DEGRO Quality of Life Work Group" ppt

... stress and job satisfaction of physicians, radiographers, nurses and physicists working in radiotherapy: a multicenter analysis by theDEGROQualityofLifeWorkGroupSusanne Sehlen*1,DirkVordermark2,ChristofSchäfer3, ... stress and job satisfaction of cancer care workers within the context of different radiotherapy departments in Germany and Austria.Methods and study populationsRecruiting of radiotherapy facilitiesRadiotherapy ... patient'sdeath and suffering [11].These imbalances with increasing demand of human and material resources on the one hand side and a lack of sufficient financial sources on the other side haveproduced a...

Báo cáo khoa học: Reconstruction ofde novopathway for synthesis of UDP-glucuronic acid and UDP-xylose from intrinsic UDP-glucose inSaccharomyces cerevisiae pptx

... UGD1-VSV-G-EcoRI-F(5¢-AGAATTCATGTATACTGATATTGAAATGAATAGATTGGGTAAAATGGTGAAGATATGCTGCATAGGAG-3¢) and UGD1-SalI-R (5¢ -AAAAAGTCGACTCATGCCACAGCAGGCATATCCTT-3¢); for UGD1-His, UGD1-His-EcoRI-F (5¢-AGAATTCATGCATCACCATCACCATCACATGGTGAAGATATGCTGCATAG-3¢) ... (5¢-AGAATTCATGCATCACCATCACCATCACATGGTGAAGATATGCTGCATAG-3¢) and UGD1-SalI-R, UXS3-EcoRI-F (5¢-AGATTCATGGCAGCTACAAGTGAGAAACAGA-3¢); and for UXS-c-Myc, UXS3-c-Myc-XhoI-R (5¢-TCTCGAGTTACAAATCTTCTTCAGAAATCAATTTTTGTTCGTTTCTTGGGACGTTAAGCCTTAG-3¢). ... reduced to approximately 54% relative to that in W30 3a strain (Fig. 3B and Table 1). In contrast, in the TOY3 strain, the amount of UDP-Glc was comparableto that in the W30 3a strain. To gain a better...

Báo cáo khoa học: Enzymes that hydrolyze adenine nucleotides of patients with hypercholesterolemia and inﬂammatory processes potx

... [9].Platelets also accumulate within atheroscleroticlesions, and can recruit additional platelets to form a thrombus, indicating that the arterial wall can assumeboth an in ammatory and prothrombogenic ... samples and standards of malondial-dehyde were read at 532 nm against the blank of the stand-ard curve. The results were expressed as nmolmalondialdehydeÆmL)1.Protein determinationProtein was ... and the importance of such hydrolysis. In line with this, literature data indi-cate that adenine nucleotides and adenosine areimportant modulators of atherosclerosis [18], and that upregulation...

Báo cáo khoa học: Mapping contacts between regulatory domains of skeletal muscle TnC and TnI by analyses of single-chain chimeras potx

... contraction [7]. The isolated N and C domains of TnC maintain their structural and functional characteristics [8] and calcium binding toN domain of TnC causes a conformational changethat exposes ... both in the presence and in the absence of calcium. On the other hand the TnI inhibitory and C-terminal domains were completelydigested by trypsin in the absence of calcium while the addition of ... Strong binding; + weak binding [16].c The actomyosinATPase activity in the presence of the binary complex formed by TnI and TnC and in the absence of calcium is 40% [10,16].dMeasured by SAXS.Fig....

Báo cáo khoa học: Studies on the regulatory properties of the pterin cofactor and dopamine bound at the active site of human phenylalanine hydroxylase pptx

... the hPAHÆadrenaline/dopamine binary complex [17] was superimposed onto that of the ligand-free rPAH containing the regulatory and catalytic domains [19] the catecholamine main-chain is alsoFig. ... protein kinase. Comparison of the inhibitoryproperties of the natural cofactor with the available three-dimensional crystal structure information on the ligand-free, the binary and the ternary ... binding of biopterin cofactor and amino acid substrateInternal protein dynamics are intimately connected to the catalytic activity of PAH, and our recent structural studieson hPAH have revealed...

Báo cáo khoa học: Hyperefficient PrPSc amplification of mouse-adapted BSE and scrapie strain by protein misfolding cyclic amplification technique pptx

... PrPScamplification of mouse-adaptedBSE and scrapie strain by protein misfolding cyclicamplification techniqueAiko Fujihara, Ryuichiro Atarashi, Takayuki Fuse, Kaori Ubagai, Takehiro Nakagaki, NaohiroYamaguchi, ... and R. Atarashi, unpublished data). Of note, small amounts of detergent-insoluble and PK-resistant PrP aggregates have been reported in unin-fected human brains in the presence of EDTA and deter-gent ... in an increasedrisk of contamination. Furthermore, although mildamplification has also been demonstrated in othermammalian species, such as mice, cervids and humans, the amplification levels in...

Báo cáo khoa học: The allene oxide cyclase family of Arabidopsis thaliana – localization and cyclization ppt

... TTCTTCTGCTGCTAT-3¢, and 5¢-TATGTCGACATTAGTAAAGTTACTTATAAC-3¢; and AOC4,5¢-TATCTAGATGATCATGGCTTCTTCTGCTGC-3¢, and 5¢-TATGTCGACATTAGTAAAGTTAGCGATC-GT-3¢), with additional XbaI and SalI restrictionsites. ... (AOC1,5¢-TATCTAGATGGCTTCTTCTACAATCTCTCT-3¢, and 5¢-TATGTCGACATTTGTAAAGTTGCTTACAAC-3¢; AOC2,5¢-TATCTAGATGGCTTCTTCAGCAGTGTC-3¢, and 5¢-TATGTCGACGTTGGTATAGTTACTTATAACTC-3¢; AOC3,5¢-TATCTAGATGGCTTC ... reaction.Cellular distribution of AOS and AOC1–AOC4All four AOCs of A. thaliana, as well as the Arabidop-sis AOS, are predicted to be localized in the chloro-plast and to contain appropriate N-terminal...

Báo cáo khoa học: "Old colchicine-induced polyploid materials of Betula pendula Roth and Betula pubescens Ehrh." docx

... Valanne,1972). On the other hand, the cell size of colchicine polyploids is greater (Table II), and the leaves and leaf organs are greaterthan at the diploid level. The ... thicker than those of diploidones, containing more parenchymatous and vascular tissue. In the tetraploids, the cell size of the parenchymatous tissuewas greater in relation ... had thinnerwalls than in the diploids. The guard cells of the stomata weresignificantly longer in the induced poly-ploids than in the colchicine-treated chro-mosomally...

Báo cáo khoa học: "Prescreening based on the presence of CT-scan abnormalities and biomarkers (KL-6 and SP-D) may reduce severe radiation pneumonitis after stereotactic radiotherapy" docx

... 5:32http://www.ro-journal.com/content/5/1/32Page 2 of 9 The progression of radiation-induced damage is the result of an early activation of an inflammatory reactionleading to the expression and maintenance of an elevatedcytokine cascade ... SK-Sdrafted the manuscript. AT, KO, AH, and RW reviewed the data and revised the manuscript. KO and KN designed the study and revised the final version. Allauthors have read and approved the final version ... symptomatic and notinterfering with activities of daily living (ADL); Grade 3,radiographic findings plus symptomatic and interferingwith ADL or O2 indicated; Grade 4, radiographic findingsplus life- threatening...

Báo cáo khoa học: Broad antibiotic resistance proﬁle of the subclass B3 metallo-b-lactamase GOB-1, a di-zinc enzyme potx

... reverse:(5¢-GATCTTGCTGCTTACTAACGCTCACTACGACCATACAGG-3¢)(5¢-GCACCTGTATGGTCGTAGTGAGCGTTAGTAAGCAGC-3¢)For the Q116H mutant forward and reverse:(5¢-GATCTTGCTGCTTACTCATGCTCACTACGACCATACAGG-3¢)(5¢-GCACCTGTATGGTCGTAGTGAGCATGAGTAAGCAGC-3¢)Production ... mutant, the presence of analanine or an asparagine residue at position 116decreased the ability of the latter mutants to chelate a zinc ion in the AHH or NHH site. Indeed, in the absence of added ... presence of increasing concentrations of zinc and the determination of KD2Activity was measured in the presence of increasing concen-trations of zinc at 30 °Cin20mm sodium cacodylate bufferpH...

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