Báo cáo khoa học: "A phase I radiation dose-escalation study to determine the maximal dose of radiotherapy in combination with weekly gemcitabine in patients with locally advanced pancreatic adenocarcinoma" doc
... and
late toxicity. As in our study, the acute toxicity consisted of
dose- limiting GI toxicity. Application of the linear quad-
ratic model indicates that 42 Gy in 2.8 Gy-fractions is bio-
logically ... considerations
The study intent was to determinate the DLT of escalating
doses of RT delivered concurrently with a fixed dose of
gemcitabine (300 mg/m
2
) adm...
... patients including phase II and III
trials comparing different agents in the treatment of radi-
ation dermatitis. In one Phase III trial, 194 female patients
receiving breast or chest-wall irradiation ... Application of the cream was accomplished with
the ventral surface of the fingers using a rotary motion of
the fingers with light pressure to the skin....
... been
obtained in phase I studies using cisplatin -combination
CTRT with either topotecan o r tira pazamine [60-62].
Several phase I/ II studies are currently investigating the
combination cisplatin-topotecan ... trial 0219 is
testing the added value of tirapazamine to cisplatin for
CTRT in carcinoma of the cervix.
Therateofgastrointestinal(GI)toxicityinourstudy
man...
... It is likely that the typing information of additional
markers in this chromosomal region improves the ordering capabilities of a
given mapping panel, leading to the revision of previous findings.
The ... markers within the
linkage groups are indicated at the far right side. Markers that connect ordered linkage
groups protrude on the right side of the middle axis. L...
... intuitive touchable
user interface in order to either learn more
about the content of a topic or to interactively
expand a topic with newly computed related
topics.
In the first step, the topic graph is ... measure of association
strength is based on the pointwise mutual in-
formation between chunk pairs which explic-
itly takes their distance into account. An ini-
tial...
... perceptron.
will describe it in detail in Section 4. In this ar-
chitecture, knowledge sources that are intractable to
incorporate into the perceptron, can be easily incor-
porated into the outside linear ... predicating
fails.
3.2 Training Algorithm
We adopt the perceptron training algorithm of
Collins (2002) to learn a discriminative model map-
ping from inputs x ∈ X to...
...
the initial rules (i. e. lexicalized rules), in which the
lexicalized TSRs model all non-syntactic phrase
pairs with rich syntactic information. In addition,
we find that the number of initial ...
defines a kind of auxiliary rules to integrate forest-
to- string rules into tree -to- string models. One prob-
lem of this method is that the auxiliary rules are
not des...
... properties of a pattern into account:
• domain relevance: its distribution in the rele-
vant documents and irrelevant documents
(documents in other domains);
• trustworthiness of its origin: the ... assigned the argument role infor-
mation and a unique id.
Step2: For i= 2 to n: (depicted in Figure 3)
1. find the set of the lowest nodes N
1
in t that
dominate...
... homodi-
merization of CARP [49]. We therefore propose that
the loss of CARP dimerization promotes the binding to
titin by improving the accessibility of the titin-binding
domain. Interestingly, the importance ... stimulation activates
the interaction of a protein complex with the kinase
domain of titin, reducing the nuclear translocation of
the transcription...
... set of indices of the partially-established entities to
the left of (note that ), and
the set of the partially-established entities. The link
model is then
(1)
the probability linking the active ... mention
is linked with an in- focus partial entity while dashed
arrows indicate starting of a new entity.
added in the next step by either linking to the exist...