Báo cáo khoa học: " Neuropsychological testing and biomarkers in the management of brain metastases" doc
Báo cáo khoa học: " Neuropsychological testing and biomarkers in the management of brain metastases" doc
... decline in neurocognitive function. Ulti-mately, combining the outcomes of neuropsychological testing, biomarkers and imaging will help us improve the management of these patients.Competing interests The ... lev-els of certain proteins or neurotransmitters in the blood orurine may be indicators of CNS damage caused by inva-sion of brain metastases and/ or radiation induced dam-age. Much of the work ... modifier of hemoglobin that works by decreasing the binding affinity of hemoglobin to oxygen thus permitting greater oxygen-ation of hypoxic tumor cells and enhancing the effect of radiation. In addition...
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Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc
... molecules,including cyclins, cyclin-dependent kinases, their inhib-itors and the retinoblastoma protein (RB), as well asE2Fs.E2F and RB family members appear to participate in the regulation of cell-cycle ... December2010)doi:10.1111/j.1742-4658.2010.07980.x The escalating prevalence of obesity is one of the most pressing healthconcerns of the modern era, yet existing medicines to combat this globalpandemic are disappointingly limited in terms ... inhibitors include two fami-lies of proteins, the Cip (Kip) family and Ink4 family, and are central players in the exit of cells from the cellcycle [11]. Loss of p27Kip1or p21Cip1 in mice leads...
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Tài liệu Báo cáo khoa học: Domain deletions and substitutions in the modular protein evolution doc
... domain deletions are more com-mon at either of the protein termini, and that theiroccurrence is slightly higher at one of the termini,depending on the number of domains in the protein and the ... C−terminusLength of the N terminus in % of the deleted domainLength of the C terminus in % of the deleted domainPfam, N−terminus Pfam, C −terminusNumber of occurencesNumber of occurences2500035000550000 ... for the proteins with the complete arrangement. To take into account the variability of the length of the complete domain, the length of the N-terminal fragment was definned as the length of the amino...
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Báo cáo khoa học: "Case markers and Morphology: Addressing the crux of the fluency problem in English-Hindi SMT" pot
... create Hindilanguage models using the target side of the train-ing corpus.Training, tuning, and decoding were performedusing the Moses toolkit3. Tuning (learning the λ values discussed in section ... pre-dominantly SOV in its word-order, correct casemarking is a crucial part of making translationsconvey the right meaning.801Proceedings of the 47th Annual Meeting of the ACL and the 4th ... likely. The separation of the lemma and suffix helps in tiding over the data sparsity problem by allowing the systemto reason about the suffix-case marker com-bination rather than the combination of...
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Báo cáo khoa học: Oxidative stress is involved in the permeabilization of the inner membrane of brain mitochondria exposed to hypoxia/reoxygenation and low micromolar Ca2+ Lorenz Schild1 and Georg Reiser2 doc
... reperfusion in brain. There is a growing body of information concerning the mechanism of ROS generation by the respiratorychain in mitochondria. Complex I and complex IIIwere identified as generators of ... degree of protection by ADP sug-gests that the mitochondrial injury is caused by open-ing of the mPTP. There is evidence that ADP inhibitsopening of the mPTP by occupying binding siteslocated in ... and oxygen consumptionwas analysed. The corresponding values are shown in Fig. 1. After 15 min of incubation in the presence of 3.5 lm Ca2+ in an air atmosphere, state 3 respiration of brain...
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Báo cáo khoa học: Membrane compartments and purinergic signalling: the role of plasma membrane microdomains in the modulation of P2XR-mediated signalling pot
... (glycero-)sphingolipids. In addition the fatty acid chains of the phospholipids composingthese rigid domains are generally more saturated thanthose in the lipids of the surrounding membrane. In fact, this ... cluster in response to extracellular stimuli and the size of the domains containing those clusters has been estimated. In summary, multiple lines of evidence have helped toargue in favour of the ... ecto-nucleotidases in lipid rafts would promote the acceler-ated degradation of ATP to ADP and adenosine in the periphery of these microdomains. ADP and adenosine would activate respectively P2Y and P1...
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Báo cáo khoa học: "Combining Distributional and Morphological Information for Part of Speech Induction" doc
... states of the model does not reduce the conditional en-tropy of the gold standard tags; rather it increases the lexical ambiguity of the model H(TIW). Thisis because the states of the HMM ... at the conditional entropy of the gold standard tagsgiven the induced tags. We use the symbol W torefer to the random variable related to the word, Gfor the associated gold standard tag, and ... all) in the training data. In addition we areinterested primarily in inducing small numbers of clusters (at most 128) from comparatively smallamounts of data using limited or no sources of external...
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Báo cáo khoa học: "Parental attitudes and opinions on the use of psychotropic medication in mental disorders of childhood" docx
... They then experience a process of grief and the acceptance of pharmacotherapy seems to coincidewith the acceptance of the psychiatric diagnosis. It is the final proof of what they fear. They ... change the attitude of the parents is whether they themselves would accept med-ication [13,14]. In the literature there are only a few reports regarding the attitudes and opinions of the general ... inform the par-ents on the efficacy and safety of treatment, and then takeinto consideration the opinions and attitudes of the fam-ily. Only by paying attention to the desires, fears and beliefs...
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Báo cáo khoa học: " Intensity modulated radiotherapy (IMRT) in the treatment of children and Adolescents - a single institution''''s experience and a review of the literature" pps
... of the children. HB is responsiblefor the anaesthesia management of the children. PH isresponsible for the clinical treatment of the children ashead of the division of radiation oncology in ... photon, electron and IMRT techniques in the treatment of intraocular retinoblastoma [30]. The bestsparing of the bony orbit was achieved with IMRT yieldinga promising potential of avoiding asymmetrical ... head -and- neck tumors since the sensitivestructures like eyes, brain stem, parotid glands or innerears represent an extraordinary challenge in the radiother-apeutic management. Starting with the...
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Báo cáo khoa học: "PARSING VS. TEXT PROCESSING IN THE ANALYSIS OF DICTIONARY DEFINITIONS" pot
... less than the eight man-months spent developing and testing the LSP definition grammar. Tagging and head finding were performed on a sample of 2157 noun definition texts, covering the nouns ... working on improving the head finder, as well as developing similar "grammars" for posmominal phrases and for the major phrase str~tures of other definition types. In the course of ... the node to the right of the taxonomy marker 'W") serving as a pointer to its own defining node. The resulting network is quite dense. We simplify by leaving out other parts of the...
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