Báo cáo khoa học: "A single centre experience with sequential and concomitant chemoradiotherapy in locally advanced stage IV tonsillar cancer" doc

... 5:121http://www.ro-journal.com/content/5/1/121Page 9 of 10RESEARC H Open AccessA single centre experience with sequential and concomitant chemoradiotherapy in locally advanced stage IV tonsillar cancerRobin J D Prestwich*†, Kiran Kancherla†, ... 2001,127(2):135-9.doi:10.1186/1748-717X-5-121Cite this article as: D Prestwich et al.: A single centre experience with sequential and concomitant chemoradiotherapy in locally advanced stage IV tonsillar cancer. Radiation Oncology 2010 5:121.Submit ... al: Concomitant chemoradiotherapy versus induction docetaxel, cisplatin and 5 fluorouracil (TPF) followed by concomitant chemoradiotherapy in locally advanced head and neck cancer: a phase II randomized...

Báo cáo khoa học: A single EF-hand isolated from STIM1 forms dimer in the absence and presence of Ca2+ ppt

... developpredicative tools for predicting the role of Ca2+ and Ca2+-binding proteins in biological systems.Materials and methodsMolecular cloning and modelling of engineeredCD2.STIM1.EFThe single EF-hand ... Ca2+-coordinating residues in positions 1 and 3 of the EF-hand motif signiﬁcantlycompromised the metal-binding capability of the engi-neered protein, indicating that the metal binding ofCD2.STIM1.EF ... of investigating theCa2+-binding sites in native Ca2+-binding proteins, weestablished a grafting approach to dissect their site-speciﬁc properties. This approach has been used in theinvestigation...

Tài liệu Báo cáo khoa học: "A Lexicon for Exploring Color, Concept and Emotion Associations in Language" doc

... associated with luck in China and Denmark, but with bad luck in Nigeria and Ger-many and reﬂects ambition and desire in India.Some expressions involving colors share thesame meaning across ... with red and brown, anticipation with green, fear with black, joy with pink, sadness with black, brown and gray, surprise with yel-low and orange, and ﬁnally, trust is associated with blue and ... de-scriptions in conveying emotion, obtaining adeeper understanding of the associations betweencolors, concepts and emotions may be helpful formany tasks in language understanding and gener-ation....

Báo cáo khoa học: A comparative analysis of the transcriptome and signal pathways in hepatic differentiation of human adipose mesenchymal stem cells doc

... dis-tinct narrow time interval of transcription initiation[25], and regulate transactivation of several endoderm- and hepatocyte-speciﬁc factors, including transthyretin,albumin and tyrosine aminotransferase ... °C. Finally, the chip was rinsed in 0.05· SSC beforedrying by low-speed centrifugation. For staining, the chipwas immersed in an NaCl ⁄ Pisolution containing 10 lgÆmL)1of streptavidin ⁄ ... expressCYP3A4 and MDR-1 at levels comparable to those in primary human hepatocytes.Expression of liver-selective transcription factors,such as HNFs, CCAAT ⁄ enhancer-binding proteins and GATA-binding...

báo cáo khoa học: "A rare case of xanthogranuloma of the stomach masquerading as an advanced stage tumor" ppt

... (CT) revealedthickening of the gastric wall and findings indicative of abdominalwall invasion.abFigure 2 Macroscopic examination of the specimens.a.Uponmacroscopic examination, the specimens ... immunohistochemically positive forCD68 and were non reactive with CAM5.2, AE1/3 and S-100 protein (Figure 3). The xanthogranuloma waslocated near to the gastric cancer, but w as not in con-tact with it. The ... xanthogra-nuloma combined with early gastric cancer. W hen wefind SMT of the stomach, we should bear in mind notonly neoplastic tumors but also inflammatory tumors.Further accumulation and investigation...

Tài liệu Báo cáo khoa học: A single amino acid substitution of Leu130Ile in snake DNases I contributes to the acquisition of thermal stability A clue to the molecular evolutionary mechanism from cold-blooded to warm-blooded vertebrates docx

... enzyme activities in vivo.Wefound that amphibian DNases I are characterized by a C-terminal end with a unique cysteine-rich stretch and byinsertion of a Ser residue into the Ca2+-binding site,resulting ... deoxyribonuclease isolated from bovine, ovine, and porcine pancreas. Derivation of the amino acid sequence ofovine DNase and revision of the previously published amino acidsequence of bovine DNase. J. Biol. ... Amphibian DNases I arecharacterized by a C-terminal end with a unique, cysteine-richstretch and by the insertion of a serine residue into the Ca2+-binding site. Biochem. J. 357, 473–480.15. Yasuda,T.,Awazu,S.,Sato,W.,Iida,R.,Tanaka,Y.&Kishi,K.(1990)...

Báo cáo khoa học: A single mismatch in the DNA induces enhanced aggregation of MutS Hydrodynamic analyses of the protein-DNA complexes pot

... the squelching actionof DNA following protein binding. However, interest-ingly, the protein regains a unique mode of aggrega-tion even when bound to DNA following anenhancement in the concentration ... presence ofa single mismatch, thereby generating large protein ⁄DNA complexes encompassing the mismatch.ResultsMutS interaction with MutL and stoichiometryanalyses In this study, we have investigated ... associ-ated with the molecular aggregates of mismatch repairproteins MutS, MutL in relation to their interaction with mismatch containing DNA and the ongoing ATPhydrolysis. Here we have mainly used...

Báo cáo khóa học: A single mutation that causes phosphatidylglycerol deﬁciency impairs synthesis of photosystem II cores in Chlamydomonas reinhardtii pdf

... were present in all strains (Fig. 3), although theirrelative ratios were altered in strains mf1 and mf2, exhibitingan increase in band D and splitting of band C. All of thesebands correspond ... of D2 and apoCP43 remained similar to those in the WTstrain. We noted that labelling of D1 and apoCP47 wereclearly detectable in 40 min pulses in mf1 and mf2 strains(Fig. 5B), suggesting that ... cassetteconferring spectinomycin resistance [18] excised with EcoRV and SmaI was then cloned in reverse orientation with respect to the petA coding region in p(bAC)FFFlinearized with HincIItoyieldplasmidpihK(bAC)FFF.This...

Báo cáo khoa học: A single intersubunit salt bridge affects oligomerization and catalytic activity in a bacterial quinone reductase pptx

... variants in thecrystalline state were analyzed using the msd-pisaserver [20] taking into account all the interactions ofprotein chains within the asymmetric unit as well as with symmetry equivalent ... enzymaticproperties. Closer inspection, however, revealed that aglycine-rich loop in the vicinity of the isoalloxazinering system with Gly106 directly interacting with C(2=O) of the pyrimidine moiety shows ... chromatographywere veriﬁed by native PAGE, in accordance with thestandard procedures for SDS-PAGE, using 12.5% separat-ing gels and 5% stacking gels. The gels and the runningbuffer, respectively lacked SDS...

Báo cáo khoa học: A single mutation in Escherichia coli ribonuclease II inactivates the enzyme without affecting RNA binding pot

... co-ordina-tion with the subsequent loss in activity, withoutaffecting substrate binding. Our band-shift experimentsdemonstrate that the RNA binding of the D209Nmutant is not reduced and not in uenced ... metal binding inhibitor (10 mmEDTA). In some cases, these metal ligands can be sub-stituted with a water molecule or by another acidicresidue in the vicinity, allowing the metal binding even in ... seem to be involved in substrate binding. Nocleavage activity was detected either with the linearpolyadenylic acid substrate or with stem–loop contain-ing RNAs (SL9A or malE-malF RNAs) in the...

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