Báo cáo khoa học: "Treatment planning using MRI data: an analysis of the dose calculation accuracy for different treatment regions" ppt

... 5:62http://www.ro-journal.com/content/5/1/62Page 2 of 8RESEARC H Open Access Treatment planning using MRI data: an analysis of the dose calculation accuracy for different treatment regionsJoakim H Jonsson2*, ... for the different calculation geometries using the clinical treatment plan and (ii) comparison of the number of monitor units (MUs) required t o reach the prescribed dose with the different calculation ... MRI data: an analysis of the dose calculation accuracy for different treatment regions. Radiation Oncology 2010 5:62.Submit your next manuscript to BioMed Centraland take full advantage of: ...

Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx

... required for insulin-induced membrane translocation of PDK-1 andAkt activation in transfected HEK cells [14]. On the other hand, the functional signiﬁcance of the inter-action of Grb14 with tankyrase ... Although the interaction of Grb14 with the IR is probably the major determi-nant of the insulin-induced membrane translocation of Grb14, several lines of evidence suggest that the associ-ation of ... 0537 ⁄ 8). We thank Dr Gillian Dan-ielsen for her supply of superactive insulin analogs, DrBarry Posner for his gift of bpV(phen), and Dr RonaldKohanski for his gift of reduced and carboxyamidome-thylated...

Tài liệu Báo cáo khoa học: P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity pptx

... responsible for the stimulatory effect on DAT.DAT belongs to the family of neurotransmittertransporters that includes the norepinephrine and sero-tonin transporters (NET and SERT), which share arange ... Determination of Vmaxand Km for DAT, NET and SERT in the presence and absence of p25a. HEK-293-MSR cells were tran-siently transfected with DAT, NET or SERT and with p25a or mockvector. The cells ... preferential degeneration of the dopamine-producing neurons of the brain stem substantia nigra. Imbal-ances between mechanisms governing dopamine transport across the plasma membrane and cellular storage...

Tài liệu Báo cáo khoa học: Mixed lineage leukemia: a structure–function perspective of the MLL1 protein ppt

... induce the cor-rect conformation of the active site [26], which is con-sistent with the poor catalytic activity of the isolatedMLL1 SET domain. However, an analysis of crystalpacking forces ... extent the observed confor-mation of the isolated MLL1 SET domain in the crys-tal structure represents the range of possibleconformations that may exist in solution.Consistent with the conformational ... [32].These experiments begin to provide a picture of how the recruitment of MLL1 can increase the binding of other important transcriptional activators that ulti-mately could result in the synergistic...

Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain pdf

... the concomitant binding of Zn, leading to the for- mation of SDS-soluble monomeric zinc-bound Ab andsoluble copper-bound GIF [38]. Therefore, the metalswap led to simultaneous modiﬁcation of ... MT isoform has different anddistinct functions within the brain. Furthermore, the discovery and continued investigation of this brain-spe-ciﬁc MT isoform has led to intense interest in the roles of ... neurodegenerative disease.Synthesis and secretion of GIF in the brainCellular and temporal localization of GIFsynthesisWhilst the MT1 and MT2 isoforms are ubiquitouslysynthesized throughout most...

Tài liệu Báo cáo khoa học: Temperature and phosphate effects on allosteric phenomena of phosphofructokinase from a hibernating ground squirrel (Spermophilus lateralis) pptx

... changes in the extent to which the binding of allosteric ligandmodifies the affinity of enzyme for substrate. The Hanes–Wolf plot in Fig. 3(B) conclusively demon-strates that the Kmvalue for ... (Ea) values for the 3–15 °C tempera-ture range of the plots were 103.2 ± 0.2 and80.0 ± 1.2 kJ mol)1in the absence and presence of phosphate. For the 15–45 °C temperature range, the Ea values ... 0.18aSignificantly different from the corresponding value at 0 mM phosphate using one-way analysis of variance with the Student–Newman–Keuls test (two-tailed), P < 0.01;bsignificantly different...

Tài liệu Báo cáo khoa học: "What lies beneath: Semantic and syntactic analysis of manually reconstructed spontaneous speech" pdf

... coreargument regions of an utterance rather than in op-tional modifying material.Reconstructive insertions751Proceedings of the 47th Annual Meeting of the ACL and the 4th IJCNLP of the AFNLP, pages ... reconstruction of this text wouldtransform these errorful utterances intoﬂuent strings and offer an alternate mech-anism for analysis. Our investigation of naturally-occurringspontaneous speaker ... reorderings anddeletion of the less informative lexemes.These examples show varying degrees of difﬁ-culty for the task of automatic reconstruction. Ineach case, we also see that semantic analysis of...

Tài liệu Báo cáo khoa học: "Identifying Linguistic Structure in a Quantitative Analysis of Dialect Pronunciation" docx

... aggregate analysis of Bulgarian di-alects on one hand, and the identiﬁcation of linguis-tic structure in the aggregate analysis on the other. Inthis section the work closely related to the one ... papers the identiﬁcation of linguistic structurein the aggregate analysis is based on the analysis of the pronunciation of the vowels found in the data set.In work presented in this paper the ... detail.2.1 Aggregate Analysis of BulgarianDialectometry produces aggregate analyses of the dialect variations and has been done for different languages. For several languages aggregate analyseshave...

Tài liệu Báo cáo khoa học: "Prosodic Aids to Syntactic and Semantic Analysis of Spoken English" ppt

... word string. Exchanges between the parser and the SR are needed for handling situations where an ill- formed utterance gets further distorted by the SR. In these cases other knowledge sources ... purpose of utterances and their domain context, it is then possible to correct some of the insertion and mis-recognised word errors from the SR and determine the com- municative intent of the ... grammar they use to change all the rules of the form A -> B C to the form A -> B Link C, and add con- straints to the rules application in terms of the value of the =breaking indices"...

Báo cáo khoa học: Physicochemical properties and distinct DNA binding capacity of the repressor of temperate Staphylococcus aureus phage /11 doc

... affinity of CI to the two operators, and the mecha-nism of action of CI. In the present study, we report the purification of /11 CI to near homogeneity and, for the first time, present evidence for the ... regu-late the transcription of genes located on the two sides of the /11 cI-cro intergenic region. Furthermore, the information gathered in the present study may proveuseful in the construction of ... majorgroove of the DNA helix [1]. Therefore, the data alsosuggest that the interaction between CI and the opera-tor DNA may occur through the major groove of the operator DNA helix. The absence of detectable...

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