Báo cáo y học: "Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients" potx
Báo cáo y học: "Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain"
... significantly shorter in the CCI rats compared with sham controls. Mechanical allodynia and thermal hyperalgesia in- duced by CCI was attenuated by intrathecal adminis-tration with TLR4 -siRNA (p<0.05, ... Conclusions/Significance: These findings suggest that suppression of TLR4 mediated by intrathecally administered siRNA may be a new strategy for the treatment of neuropathic pain. Key words: Toll-like receptor ... transfection reagent (Neuromics, Edina, MN, USA) was administered intrathecally once daily for 7 days, starting from 1 day before CCI surgery. Evaluation of tactile allodynia and thermal hyperalgesia...
- 9
- 487
- 0
Báo cáo y học: "Association between antipsychotics and weight gain among psychiatric outpatients in Pakistan: a retrospective cohort study" ppsx
... and weight gain among psychiatric outpatients in Pakistan: a retrospective cohort studySyed Ahmer*1, Rashid AM Khan1 and Saleem Perwaiz Iqbal2Address: 1Department of Psychiatry, Aga ... Aga Khan University, Karachi, Pakistan and 2Department of Paediatrics & Child Health, Aga Khan University, Karachi, PakistanEmail: Syed Ahmer* - syed.ahmer@aku.edu; Rashid AM Khan - rashid.masud@aku.edu; ... started appear-ing[6]. Since then many studies have been publishedfirmly establishing a clear link between antipsychotics and diabetes mellitus, more with atypical than typicalantipsychotics...
- 4
- 330
- 0
Báo cáo y học: "Antibodies to mutated citrullinated vimentin for diagnosing rheumatoid arthritis in anti-CCP-negative patients and for monitoring infliximab therapy" ppt
... not for citation purposes)Vol 10 No 6Research articleAntibodies to mutated citrullinated vimentin for diagnosing rheumatoid arthritis in anti-CCP-negative patients and for monitoring infliximab ... enzyme immunoassay; ELISA: enzyme-linked immunosorb-ent assay; MCV: mutated citrullinated vimentin; PTPN22: protein tyrosine phosphatase nonreceptor type 22; RA: rheumatoid arthritis; RF: rheumatoid ... released in increased amounts in response to growth factors and proinflammatory cytokines, suggestinginvolvement in the pathophysiology of RA [24]. The few stud-ies of anti-MCV usually found performance...
- 7
- 413
- 0
Báo cáo y học: "New insights into integrin signalling: implications for rheumatoid arthritis synovial fibroblasts" pptx
... transfer to synoviocytes andosteoclasts. J Clin Invest 1999, 104:137-146.14. Pap T, Franz JK, Hummel KM, Jeisy E, Gay RE, Gay S: Activationof synovial fibroblasts in rheumatoid arthritis: lack ... cultured rheumatoid synoviocytes. JRheumatol 1995, 22:817-828.12. Morel JC, Park CC, Zhu K, Kumar P, Ruth JH, Koch AE: Signaltransduction pathways involved in rheumatoid arthritis syn-ovial ... invasion of articular cartilage by rheumatoid synovial fibroblasts is inhibited by antibodies to specific inte-grin receptors and by collagenase inhibitors. Arthritis Rheum1997, 40:1298-1307.10....
- 2
- 251
- 0
Báo cáo y học: "Improved cartilage integration and interfacial strength after enzymatic treatment in a cartilage transplantation model" potx
... 5Research articleImproved cartilage integration and interfacial strength after enzymatic treatment in a cartilage transplantation modelJarno van de Breevaart Bravenboer1, Caroline D In der Maur2, ... constructs.Discussion In the present study we found an improvement in histologi-cal and biomechanical integration of articular cartilage after treatment with a combination of hyaluronidase and collagenase, a protocol ... wound healing and integration may be a causeof potential failure of otherwise promising techniques.Injury to cartilage results in the formation of an acellular and thus metabolically inactive...
- 8
- 477
- 0
Báo cáo y học: "Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients" potx
... single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patientsMatthias Pierer, Sylke Kaltenhäuser, Sybille Arnold, Matthias ... providefurther evidence that the PTPN22 1858T allele is associated with RA irrespective of autoantibody production. The increased frequency of the risk allele in male patients and its association with ... frequencies of the variant PTPN22 1858T allele in RA patients and healthy controls areshown in Table 1.All genotypes containing the rare 1858T allele were found atincreased frequencies in RA patients....
- 7
- 420
- 0
Báo cáo y học: " Antibodies to mutated citrullinated vimentin for diagnosing rheumatoid arthritis in anti-CCP-negative patients and for monitoring infliximab the" pdf
... released in increased amounts in response to growth factors and proinflammatory cytokines, suggestinginvolvement in the pathophysiology of RA [24]. The few stud-ies of anti-MCV usually found performance ... widely expressedby mesenchymal cells and macrophages and easy to detect in the synovium. Modification of the protein occurs in macro-phages undergoing apoptosis, and antibodies to citrullinated vimentin ... Berglin E, Rantapää-Dahlqvist S: Antibodies against mutated citrullinated vimentin are a better predictor of disease activity at 24 months in early rheumatoid arthritis than antibodies against cyclic...
- 7
- 342
- 0
Báo cáo y học: "Offensive’ snakes: cultural beliefs and practices related to snakebites in a Brazilian rural settlement" docx
... substance as anantivenom is both historically ancient and geographicallyTable 3 Charms related to snakebites, according to the inhabitants of the county of Pedra Branca, Bahia State, Brazil.Charms ... pricking are synonymous and used asequivalent to offending. In this artic le, the word offensemeans a direct injury, real and/ or imaginary, caused byany animal to a person, seriously jeopardizing ... Beliefs related directly or indirectly to the injuries (real and/ or imaginary) caused by snake bites, according to the dwellers of the county of Pedra Branca, Santa Terezinha, Bahia State, Brazil.Beliefs...
- 13
- 461
- 0
Báo cáo y học: "Cor triatriatum presenting as heart failure with reduced ejection fraction: a case report" pptx
... bypas s (CPB) was achieved by standardascending aorta and bicaval cannulation. Mildlyhypothermic (32°C) CPB was established. Cold blood car-dioplegia was administered in an antegrade fashionthrough ... triatriatum. Cathet Cardiovasc Diagn 1992, 25:323-6.doi:10.1186/1749-8090-6-83Cite this article as: Kokotsakis et al.: Cor triatriatum presenting as heart failure with reduced ejection fraction: ... patient was asymptomatic(NYHA class I), in sinus rhythm. TTE and MRI revealed a mildly dilated LV with great improvement in systolicfunction and an estimated LVEF of 50%.DiscussionCor triatriatum...
- 4
- 392
- 0
Báo cáo y học: "Delayed intracardial shunting and hypoxemia after massive pulmonary embolism in a patient with a biventricular assist device" pdf
... CAS E REP O R T Open AccessDelayed intracardial shunting and hypoxemia after massive pulmonary embolism in a patient with a biventricular assist deviceThomas Weig1*, Michael E Dolch1, ... monthspostpartum on a cardiac biventricular assist device (BVAD) as bridge to heart transplantation with delayed onset of intracardial shunting and subsequent hypoxemia due to massive pulmonary embolism. ... cardiopul-monary bypass and after LVAD activation [12,13]. Alter-natively, manual occlusion of the pulmonary arteryshortly before activatio n of the LVAD by the surgeon and transesophageal...
- 4
- 379
- 0
Báo cáo y học: "Association between isotretinoin use and central retinal vein occlusion in an adolescent with minor predisposition for thrombotic incidents: a case report" doc
... purposes)Journal of Medical Case ReportsOpen Access Case reportAssociation between isotretinoin use and central retinal vein occlusion in an adolescent with minor predisposition for thrombotic incidents: ... documented case of this association. Case presentation: An otherwise healthy 17-year-old white man who was treated with systemic isotretinoin for recalcitrant acne was referred with central retinal vein ... a case reportGeorgios Labiris*1, Andreas Katsanos1, Maria Karapetsa2, Ioanna Mpanaka2 and Dimitrios Chatzoulis1Address: 1Ophthalmology Department, University Hospital of Larissa,...
- 5
- 243
- 0
Báo cáo y học: " Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B" pps
... purposes)NTHi-induced COX-2 and PGE2 expression mediated by p38 MAPK and NF-kappa B signaling pathwayTo determine the role of NTHi-induced p38 MAPK and NF-kappa B activations in NTHi-induced COX-2 and PGE2 ... the inhibition of p38 MAPK. Conclusion: NTHi induces COX-2 and PGE2 expression in a p38 MAPK and NF-kappa B-dependent manner through TLR2 in lung epithelial cells in vitro and lung tissues in ... induced COX-2 expression was mediated by TLR2 in the epithelial cell in vitro and in the lungs of mice in vivo. NTHi induced phosphorylation of p38 MAPK and up-regulated DNA binding activity of NF-kappa...
- 9
- 290
- 0
Báo cáo y học: "Circulating immune complexes and complement C3 and C4 levels in a selected group of patients with rhinitis in Lebanon" pot
... (65.5%).Dermatophagoides pteronyssinus (Dpt) was the causativeallergen in 62, Dermatophagoides farinae (Df) in 58, cathair dander in 23 and dog hair dander in 9 patients (some patients were allergic ... because C3 and C4 levels were within thenormal range in all patients tested (Table 1). In support of the lack of involvement of the classical and lectin comple-ment pathways is the study by ... infants at high risk of asthma. Lancet 2000, 13(355(9216)):1680-1683.21. Andersson M, Laukkanen M, Salkinojasalonen M: 3-Hydroxy fattyacids: Stable indicators of endotoxin in hay and straw dust.Journ...
- 4
- 221
- 0
Báo cáo y học: "Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury" pps
... Silva et al., Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury Critical Care 2010, 14:R114 Silva et al. Critical Care ... 68:585-618.33. Kulkarni AC, Kuppusamy P, Parinandi N: Oxygen, the lead actor in the pathophysiologic drama: enactment of the trinity of normoxia, hypoxia, and hyperoxia in disease and therapy. Antioxid ... properly cited.ResearchHypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injuryPedro L Silva1, Fernanda F Cruz1, Livia C...
- 16
- 287
- 0
Báo cáo y học: "Association between serum soluble CD40 ligand levels and mortality in patients with severe sepsis" potx
... procalcitonin to determine itsassociation with sCD40L levels. There are been reportedan association between sCD40L levels and severity ofacute coronary artery syndrome [31] and between tropo-nin and ... associated with mor-tality at 30 days in a large series of septic patients. We found higher serum sCD40L levels in patients with severe sepsis than in healthy controls, in agree-ment with previous ... severity. CD40 Ligand (CD40L) and its soluble counterpart(sCD40L) are pr oteins that exhibi t prothrombot ic and proinflammatory properties on binding to their cell sur-face receptor CD40 [2,3]. CD40L...
- 8
- 320
- 0
Từ khóa: Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018chuyên đề điện xoay chiều theo dạngMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)chuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)