Báo cáo khoa học: "Does the surgeon still have a role to play in the diagnosis and management of lymphomas?" docx

... squamous carcinoma as thisrequires an alternative therapeutic approach. There is a question as to the accuracy of FNAC in the diagnosis of lymphomas as the tumours often contain malignant and reactive ... study was to examine whether the 21st cen-tury surgeon still has a role to play in the diagnosis and management of lymphoma.Patients and methods The study was a retrospective study of all patients ... lymphomatous nodes corresponded to the distribution of lymphadenopathy as a whole, with the majority of palpable nodes being in the cervical, inguinal and axillary chains and as such were amenable to...

báo cáo khoa học: " Does dissemination extend beyond publication: a survey of a cross section of public funded research in the UK" potx

... collection and analysis for the study. All authors wereinvolved in the writing of the first and subsequent versions of the paper, and read and approved the final manuscript. PMW is the guarantor of the study.Competing ... importance of and appear committed to disseminating the findings of their work. Although researchers are focussed on academic publication, a range of dissemination activities arebeing applied albeit ... onresearch dissemination does enhance the uptake of research findings in policy and practice.SummaryResearchers recognise the importance of, and appearcommitted to, disseminating t he findings of...

Báo cáo khoa học: Novel diadenosine polyphosphate analogs with oxymethylene bridges replacing oxygen in the polyphosphate chain pdf

... prom-ising for the noninvasive characterization of vascular in ammation [19]. Of various Apn A analogs investigated so far aspotential substrates and/ or inhibitors of speciﬁc Ap4 A hydrolases, ... ab ,a b¢-disubstituted analogs of Ap4 A (e.g. ApCHFppCHFpA was cleaved at 3% of the rate of AppppA) [22]. They constitute a symmet-rical mode of cleavage of 5 by water attack at Pb. The failure ... orientation of the P-O-C-P linkage in the a, b active site. Takentogether, the results of cleavage of compounds 3 and 5 show that the asymmetrically acting Ap4 A hydro-lases can reach the scissile...

Báo cáo khoa học: Unique proteasome subunit Xrpn10c is a speciﬁc receptor for the antiapoptotic ubiquitin-like protein Scythe docx

... domain as a chaperone-binding region in its C-terminal region (and thereby it is also calledBAG-6) and a single UBL domain in its N-terminalregion, but the function of the latter domain remainscompletely ... domain proteins and the Rpn10 subunit of 26Sproteasome, originally called S 5a, can bind to a poly-ubiquitin chain linked to proteins in vitro [13–18].Deletional analysis of Rpn10 revealed that ... domains in bothDomain I and Domain II are involved in targeting of Scythe to Xrpn10c in vivo. These results indicate thatScythe is a novel protein that contains functional tan-dem ubiquitin homology...

Báo cáo khoa học: " Radical stereotactic radiosurgery with real-time tumor motion tracking in the treatment of small peripheral lung tumors" docx

... Shirato H, Shimzu S, Ogura S, Onimaru R, Kitamura K,Yamazaki K, Miyasaka K, Nishimura M, Dosaka-Akita H: Small-vol-ume image-guided radiotherapy using hypofractionated,coplanar, and noncoplanar ... During treatment delivery the tumorposition was tracked using the live camera array signal and correlation model, the linear accelerator was movedby the robotic arm in real time to maintain alignmentwith ... Takeda A, Kunieda E, Ishizaka A, Takemasa K, Shimada K,Yamamoto S, Shigematsu N, Kawaguchi O, Fukada J, Ohashi T,Kuribayashi S, Kubo A: Radiation injury after hypofractionatedstereotactic radiotherapy...

Tài liệu Báo cáo Y học: Granule-bound starch synthase I A major enzyme involved in the biogenesis of B-crystallites in starch granules ppt

... in Chlamydomonasstarch appeared 10- to 50-fold higher than that measured in vascular plant starches [24].We now report the cloning and characterization of cDNAs and gDNAs corresponding to a ... Strain IJ2 has been already describedelsewhere [22] and contains mutations at both the STA2 and STA3 loci. Mutation in the latter leads to the completedisappearance of the major soluble starch ... displays a typical rediodine stain. Stains of others strains result from various levels of phenotypic complementation indicating, in most cases (except for strain N), a partial restoration of amylose...

Báo cáo khoa học: Amyloid-b protoﬁbril levels correlate with spatial learning in Arctic Alzheimer’s disease transgenic mice docx

... area) and platform crossings. The escape latency at the last trial of training was subtracted from mean escapelatency at the ﬁrst day of training, to measure the improve-ment in spatial learning. ... three-wayfactorial ANOVA with genotype, age and time as categori-cal factors. After analyzing the effect of age on escape laten-cies with single variance analysis, age groups were pooled and escape ... USA). Custom-mademacros were used to measure the stained area of interest aspercentage of total tissue area.Biochemical Ab analysisCortical and cerebellar brain tissues from perfused animalswere...

Báo cáo khoa học: "Fast Online Training with Frequency-Adaptive Learning Rates for Chinese Word Segmentation and New Word Detection" docx

... requiring more than 50 passes. The ADFtraining is about an order magnitude faster than the SGD online training and more than an ordermagnitude faster than the LBFGS batch training.Finally, ... dimensionalfeatures. In the proposed training method, we try to use more reﬁned learning rates. Instead of using a single learning rate (a scalar) for all weights,we extend the learning rate scalar to a learningrate ... Instead of using a single learning rate (a scalar) for all weights, we extend the learning ratescalar to a learning rate vector, which has the samedimension of the weight vector www. The learningrate...

Báo cáo khoa học: 9-Deazaguanine derivatives connected by a linker to diﬂuoromethylene phosphonic acid are slow-binding picomolar inhibitors of trimeric purine nucleoside phosphorylase potx

... 5¢-phosphate of 5-fluoroadnenosine arabinoside, fludarabine [30], and 5¢-triphosphates of cytarabine (araCTP), gemcita-bine (dFdCTP) and floxuridine (FdUTP) [31]. Wealso plan to mark DFPP-DG with a fluorescencedye ... total ligand concentration [L], and [Eact] the total concentration of enzyme binding sites. Experimen-tal data were fitted to the above equation, using nonlinearregression analysis, obtaining ... the range 0.05–6.4 lm.Concentrations of protein and ligand refer to the situationprior to mixing in the stopped-flow apparatus (i.e. to the concentrations in the syringes, and not the final concentra-tions...

Báo cáo khoa học: "Planning target volume margins for prostate radiotherapy using daily electronic portal imaging and implanted fiducial markers" docx

... SteveAngyalfi, Alex Balogh, Siraj Husain, Harold Lau, David Skarsgard, Jackson Wu;Saskatoon Cancer Center, Saskatoon SK Canada: Ali El-Gayed, DavidSkarsgard; Cross Cancer Institute, Edmonton AB Canada: ... Canadian provinces of Alberta and Saskatchewan, to evaluate acute and latetoxicity associated with the u se of a hypofractionatedRT schedule of 55 Gy in 16 fractions over four weeks(4 fractions/week), ... the combined systematic and random error to within 3 mm along the L-R and S-I axes and 2 mmalong the A- P axis.Our image guidance procedure of taking a pre-treat-ment EPI, comparing it to the...

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