Báo cáo y học: "Clinical and functional remission: even though biologics are superior to conventional DMARDs overall success rates remain low – results from RABBIT, the German biologics register" doc
... carrying the N-linked
oligosaccharide and the core CTLD. Bands corresponding
to Glu-C and trypsin enzymes were identified on the basis of
molecular mass. The bands smaller than 14 kDa in the
trypsin ... Materials and metho ds. The top row of p hotos is of ice
crystals with their c axis in the plane of the page. The bottom row
shows ice crystals with their c axis norma...
... after
stimulation from upper and lower limbs. The statistical Analysis included 1 and 2-way MANCOVAs
and Factor analysis
Results: The N13 latency was significantly prolonged, the N19 amplitude was lower, the ...
3
Laboratory of Neurophysiology, Mental Hospital of Thessaloniki, Greece,
4
2nd
Department of Psychiatry, Aristotle University of Thessaloniki, Greece and
5
Lab...
... investigate the functional
and anatomical heterogeneity of these cell subsets in relation to
the expression of the inflammatory chemokine receptors
CXCR3 and CCR5. Memory T cells freshly isolated from the
peripheral ... be broadly
classified into two groups: inflammatory and homeostatic
[4]. The inflammatory chemokines are induced by proin-
flammatory stimuli and con...
... for their reactivity
with recombinant tissue inhibitors of metalloproteinases (TIMPs)
1 to 4 by an ELISA and were compared with blood from 62
healthy controls and 21 synovial fluid samples from ... In the present study, we show that RA
patients frequently develop autoimmune response to TIMPs that
may act as a functionally significant regulator of MMP activity
and thereby of jo...
... withdrawal of
the offending drug usually leads to resolution of the syndrome
without further therapy, whereas the IVs must always be
treated with immunosuppressive and anti-inflammatory drugs,
and sometimes ... myeloperoxidase. Twenty-
nine of these patients suffered from Wegener’s granulomatosis,
23 from microscopic polyangiitis, four from Churg–Strauss
syndrome, and 16...
... immuno-reg-
ulatory activity have been described, including T regulatory
(T
REG
) lymphocytes, and type-1 T regulatory (Tr1) cells [8,9].
T
REG
lymphocytes are characterized by the expression of CD4
and by ... (0.5 to 1.0 g at days 1 and 15) was added to the
immunosuppressive therapy and its therapeutic effect was
evaluated. In addition, the levels and function of regul...
... 1
Flow cytometry of B-cell subsets in synovial fluid (SF) and peripheral blood (PB) from juvenile idiopathic arthritis (JIA) patientsFlow cytometry of B-cell subsets in synovial fluid (SF) and ... 0.0006
a
Results represent median percentage of positive cells as assessed with flow cytometry. Values in parentheses are minimum and maximum values.
b
P values were calculated by compa...
... [12]. These obser-
vations, together with knowledge of the hierarchy of
regulatory networks, have led to the hypothesis of ‘analog’
and ‘digital’ components of gene regulation in bacteria.
The ... expression are
still not clear. Because nucleoid organization can be
described on both a physical and a functional basis, these
two properties should be analyzed and understood...
... Organization and evolutionary
trajectory of the mating type (MAT) locus in the dermatophyte and
dimorphic fungal pathogens. Eukaryotic Cell 2010, 9:46-58.
39. Aimanianda V, Bayry J, Bozza S, Kniemeyer ... ability of
dermatophytes to specifically infect superficial host
structuresmaybesupportedbythepossessionofa
broad repertoire of genes encoding hydrolytic enzymes,
the expression...