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Báo cáo y học: "Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis" pptx

Báo cáo y học:

Báo cáo y học: "Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis" pptx

... articleRegional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritisAllan A Young1, Margaret M Smith1, Susan M Smith1, Martin A ... used an ovine meniscectomy model of OA to evaluate changes in chondrocyte expression of types I,II and III collagen; aggrecan; the small leucine-richproteoglycans (SLRPs) biglycan, decorin, ... OAchondrocytes synthesize SLRPs that are differently glyco-sylated, and that nonglycosylated biglycan and decorin aremore abundant in OA cartilage [20]. Changes in glycosylation of the SLRPs, whether by...
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Báo cáo y học: "Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis" ppt

... course of the expression of prostaglandin E synthase (PGES) and cyclooxygenase (COX) isoenzymes in chondrocytes stimulated with interleukin-1β (IL-1β)Time course of the expression of prostaglandin ... (TBS-T) and 5% skimmed milk,the primary antibody (rabbit anti-human mPGES-1 anti-body, rabbit anti-human cPGES antibody, mouse anti-human COX-1 antibody, or rabbit anti-human COX-2 anti-body) ... conversion of Figure 4 Expression of membrane-associated prostaglandin E synthase (mPGES-1) and cyclooxygenase-2 (COX-2) protein in cytokine-stimu-lated chondrocytesExpression of membrane-associated...
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Báo cáo y học: "Candida albicans induces cyclo-oxygenase 2 expression and prostaglandin E2 production in synovial fibroblasts through an extracellular-regulated kinase 1/2 dependent pathway" pps

... β-glucan receptor, has a number of antimi-crobial functions in phagocytes including induction of cytokines and chemokines, possibly by collaborating withTLRs, involvement in endocytosis and phagocytosis ... chamber interaction and subsequent assessment of COX-2 gene expression in synovial fibroblasts (lanes 1 and 2) and C. albi-cans (lane 3). Lane 1: synovial fibroblasts in the upper chamber and no ... isinduced in human joint tissues, including chondrocytes and synoviocytes, by inflammatory stimuli such as interleukin 1β(IL1β), IL17, and tumor necrosis factor (TNF) [12-20] and hasroles in...
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Báo cáo y học: " Immune Restoration Syndrome with disseminated Penicillium marneffei and Cytomegalovirus co-infections in an AIDS patient" pps

... bamboo rats(Rhizomys sinensis) in Vietnam [7]. It is a facultative intra-cellular pathogen and is capable of causing disseminatedinfection in both humans and animals. It is endemic in Southeast ... Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi 110029, India and 2Department of Internal Medicine, All India Institute of Medical Sciences, New Delhi 110029, IndiaEmail: ... regression of lymph nodes and decrease in the size of liver and spleen.After 10 months of therapy, he has gained 20 kg weight,his vision is 6/6 in both eyes and his liver and spleen arenot palpable,...
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Báo cáo y học: "Health system weaknesses constrain access to PMTCT and maternal HIV services in South Africa: a qualitative enquiry" pptx

... psycho-social assistance.Across the four facilities, the training and repeat train-ing of health personnel (nurses and lay counsellors) in quality HIV and infant feeding counselling is essential.Improved ... HIV services in labour wards; ensuring quality HIV and in fant feeding counsellin g; and improvedmonitoring for performance management using robust systems for data collection and utilisation.Background In ... monitoring and evaluation for performancemana gement are equally i mportant in enhancing servicedelivery [39]. In South Africa, van der Merwe et al.underscore that strengthening linkages and integratingkey...
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Báo cáo y học: "Relationship among Dexamethasone Suppression Test, personality disorders and stressful life events in clinical subtypes of major depression: An exploratory study" pot

... Review. In Handbook of Clinical Psychoneuroendocrinology Edited by:Nemeroff CB and Loosen PT. New York, John Wiley and Sons;1987:313-335. 6. Mendlewicz J, Hubain PP, Koumakis C: Further Investigation ... and G Kaprinis1Address: 1Lab of Psychophysiology, 3rd Department of Psychiatry, Aristotle University of Thesssaloniki, Greece, 2Lab of Clin Neurophysiology, 1st Department of Neurology ... Journal of Medical Psychology 1977, 50:73-78.18. Rahe R: Stress and Psychiatry. In Comprehensive Textbook of Psychi-atry, 6th Edition Edited by: Kaplan HI and Sadock BJ. Baltimore, Wil-liams and...
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Báo cáo y học: "PLCb1-SHP-2 complex, PLCb1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling?" ppt

... from the ItalianSociety of Hypertension (SIIA) to LAC, by a grant from Italian Ministry of theUniversity and Scientific and Technological Research (MURST) to GC and bya grant and from Associazione ... I,Semplicini A, Pessina AC: Silencing regulator of G protein signaling-2(RGS-2) increases angiotensin II signaling: insights into hypertensionfrom findings in Bartter’s/Gitelman’s syndromes. J Hypertens ... blotting using antiPLCb1, anti SHP-2 and anti phospho tyrosine antibo-dies. In addition, we probed Ang II signaling processesrelated to this complex by assessing the effects of losar-tan, an Ang...
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Báo cáo y học: " High-risk HPV E5-induced cell fusion: a critical initiating event in the early stage of HPV-associated cervical cancer" pptx

... KnebelDoeberitz M: DNA aneuploidy and integration of human papillomavirustype 16 e6/e7 oncogenes in intraepithelial neoplasia and invasivesquamous cell carcinoma of the cervix uteri. Clin Cancer Res 2004,10:3059-3063.21. ... Tetraploidy and chromosomal instability are early eventsduring cervical carcinogenesis. Carcinogenesis 2006, 27:337-343.16. Incassati A, Patel D, McCance DJ: Induction of tetraploidy through loss of p53 ... progression of cervical cancer. Additionally,establishment of a role of cell fusion in carcinogenesis of cervical cancer is of reference value for understandingthe pathogenesis of other virus-associated...
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Báo cáo y học: " Candida soluble cell wall β-glucan facilitates ovalbumin-induced allergic airway inflammation in mice: Possible role of antigen-presenting cells" ppt

... alsogreater in the CSBG + OVA group than in the CSBG groupHistological findings of hematoxylin and eosin (H&E)-stained lungsFigure 2Histological findings of hematoxylin and eosin (H&E)-stained ... wasProtein levels of cytokines and chemokines in the lung homogenatesFigure 4Protein levels of cytokines and chemokines in the lung homogenates. The 4 groups of mice were intratra-cheally inoculated ... pulmonary exposureto CSBG induces lung inflammation characterized by theinfiltration of inflammatory leukocytes including eosi-nophils with an enhanced lung expression of proinflam-matory cytokines...
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Báo cáo Y học: Molecular mechanisms underlying SHP-1 gene expression potx

Báo cáo Y học: Molecular mechanisms underlying SHP-1 gene expression potx

... activity in SKOV3 cells. In our EMSA analyses, aside from the shifted band thatcontained USF1 and USF2, we observed other shiftedbands (X and Y) . As bands X and Y were only partiallyinhibited by ... and differentiation, and of pathological events such as malignanttransformation. Protein tyrosine kinases and phosphatasesare the key players in the regulation of protein tyrosinephosphorylation. ... protein tyrosinephosphatases, SHP-1 and SHP-2 are distinguished by thepresence of two tandem src-homology 2 domains. Src-homology 2 domains interact with phospho-tyrosine resi-dues in many growth...
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