Báo cáo y học: "Gene expression profiles in the rat streptococcal cell wall-induced arthritis model identified using microarray analysis" docx
Báo cáo y học: "Gene expression profiles in the rat streptococcal cell wall-induced arthritis model identified using microarray analysis" docx
... the time course study in the streptococcal cell wall (SCW)-induced arthritis in Lewis (LEW/N) ratHeat map diagram of differential gene expression in joints from the time course study in the streptococcal ... calculated by divid-ing the mean intensity signal from all the individual SCW-injected rats included in each group by the mean intensitysignal from the corresponding PBS control group. The levelof ... search analysisTemporal gene expression profiles in the reactivation model of streptococcal cell wall (SCW)-induced arthritis in rat identified using Spotfire® profile search analysis. The seven...
- 17
- 487
- 0
Báo cáo y học: "Gene expression profiles in BCL11B-siRNA treated malignant T cells" ppt
... analysis. The reason may be due to a systemic error on the microarr ay analysis. Interestingly, unlike the result fromMolt-4 cells, the alteration of the CREBBP expression level in primary T-All ... reportedachangeinCREBBP expression in T cell lines afterBCL11B-siRNA treatment. In the present study, downre-gulation of CREBBP was identified in the microarray analysis, but not confirmed by real-time ... proteins BIK and BNIP3, which werelocated upstream of BCL-2 (Figure 2), may enhancetheir binding to BCL-2, thereby inhibiting the anti-apop-totic function. Thus, we analyzed the BCL-2 proteinexpression...
- 6
- 328
- 0
Báo cáo y học: "Gene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis" doc
... baseline depending on response to therapy, weperformed immunostaining experiments on the synovial biopsyspecimens obtained from the 25 patients included in the study. We evaluated the synovial expression ... significantly overexpressed at baseline in poor responders are induced by several cytokines in FLSs,thereby suggesting a role for these cytokines in the resistanceto TNF blockade in RA.ANOVA: analysis ... treatment, thereby preventing disease progression in these patients and saving unnecessary costs.TNF antagonists interfere with many pathways involved in RAsynovial inflammatory processes; these include...
- 13
- 486
- 0
Báo cáo y học: "Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation" pps
... arthritis (RA), the gene expression profile is extremely complexowing to the diversity of cell types involved in the pathologyand the polygenic character of the autoimmune disease [1-5]. The ... high-density oligonucleotidearrays interrogating the entire mouse genome. Arthritis wasinduced in severe combined immunodeficient mice by using adoptive transfer of lymphocytes from proteoglycan-immunizedarthritic ... BALB/cmice migrate and interact with the intact innate immunityenvironment in the joints of BALB/cSCID mice. The gene expression profiles in normal, pre-arthritic and arthriticjoints of the recipient...
- 12
- 546
- 0
Báo cáo y học: "Gene expression induced by interleukin-17 in fibroblast-like synoviocytes of patients with rheumatoid arthritis: upregulation of hyaluronan-binding protein TSG-6" doc
... of interleukin-8 (IL-8) levels in joint fluids of patientswith rheumatoid arthritis and the induction by IL-8 of leuko-cyte infiltration and synovitis in rabbit joints. LymphokineCytokine ... IL-17-induced inflammation and jointdamage, implying a pathway independent of IL-1 [40]. The interaction of the cytokines IL-1β, IL-17, and TNF-α sus-tained inflammatory processes within the joint and ... Fas expression in synoviocytes [37]. The present study demonstrates the potency of IL-17, IL-1β,and TNF-α alone and also in combination to induce the syn-thesis of IL-6, IL-8, and TSG-6 by SFCs....
- 7
- 323
- 0
Báo cáo y học: "Gene expression signatures for autoimmune disease in peripheral blood mononuclear cells" potx
... activity as measured by the SLEDAI, reinforcing the hypothesis that the IFN signatureis a measure of disease activity or severity [16].Inspection of gene expression data generated in our studyof ... While early studies using this approachwere largely in oncology, many new reports are emerging in other fields including infectious diseasesand pharmacology, and applications in autoimmunity have ... groups (working in MS and SLE) by including patients with RA and IDDM,and by offering direct comparisons between them. The similar gene expression findings in these clinically diverseconditions...
- 9
- 428
- 0
Báo cáo y học: "Gene expression and activity of cartilage degrading glycosidases in human rheumatoid arthritis and osteoarthritis synovial fibroblast" potx
... glycosidaseactivities in RA joints were probably not due to enhanced gene expression of resident SFs, but rather resulted from enzymerelease by cells (including infiltrating inflammatory cells) within the joints.Competing ... [13].There is increasing evidence that SFs are key players in the pathogenesis of RA by invading and eroding hyaline cartilage.SFs, activated locally, produce a variety of cytokines, chemok-ines ... an effect. Finally, we were inter-ested in whether gene expression of the glycosidases wasinfluenced by nitric oxide. In the presence of NOC-18 therewas no change in the gene expression, except...
- 13
- 681
- 1
Báo cáo y học: "Gene expression profile and synovial microcirculation at early stages of collagen-induced arthritis" pot
... β1/β2 integrins, P-selectin is the predom-inant adhesion molecule, mediating monocyte binding toinflamed synovial venules [23]. Similarly, increased cellularinfiltration and increased expression ... circulating leucocytes, andtheir interaction with the endothelial lining followed by subse-quent transendothelial migration and infiltration into tissue rep-resent the first and determining step in ... role in diseaseremains unclear [31]. The chemokine ligand CCL-27 wasrecently shown to bind the P-selectin glycoprotein ligand 1 –a molecule that plays a role in homing of T lymphocytes [32].The...
- 9
- 429
- 0
Báo cáo khoa học: "MicroRNA expression profiles in human cancer cells after ionizing radiation" pps
... especially focusing on clinically relevant endpoints like radiation induced cell death,proliferation, migration and metastasis.IntroductionMicroRNAs are small non-coding RNAs of typically 20 -22 ... significant changes in microRNA expression profiles in 3 glioma and 3squamous cell carcinoma cell lines. The functional relevance of these changes is not addressed but should byanalyzed by future work ... to increase migrationand intra-he patic metastasis in hepatocellular carcinoma[15]. Indeed, enhanced migration of malignant gliomacells was observed in response to radiotherapy [20,21].Another...
- 5
- 191
- 0
Báo cáo y học: "Antiphospholipid antibody profiles in lupus nephritis with glomerular microthrombosis: a prospective study of 124 cases" pot
... renal tissue injuryRenal tissue injury was evaluated using activity and chronicityindices as previously reported by Austin and colleagues [34]. The activity index was the sum of the scores (on ... nephropathy, postpartum renal failure, preeclampsia, HIVinfection, or cyclosporine therapy [6,8]. The patients were informed of the purpose of the study andgave their informed consent. The institutional ... plasmin, and hinder the antithrombininactivation of thrombin. The purpose of this study was toinvestigate the prevalence of GMT in LN patients and examine the relation between the aPL profiles...
- 9
- 413
- 0
Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnmẫu báo cáo y học cổ truyềnbao cao y hoc colchicinphan ban luan trong bao cao y hoc co truyenestablishment of a gene expression programme in the hindbraingene expression profiling in the process of osteochondro inductive events in the spinestep by step in situ hybridization method for localizing gene expression changes in the brainbáo cáo khoa học y họcbáo cáo y tế học đườngmẫu báo cáo y tế học đườngbáo cáo y tế học đường cuối nămbáo cáo y tế học đường năm 2012báo cáo y tế học đường trường mầm nonbiểu mẫu báo cáo y tế trường họcBáo cáo quy trình mua hàng CT CP Công Nghệ NPVchuyên đề điện xoay chiều theo dạngMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngChuong 2 nhận dạng rui roTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2chuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)Chiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015HIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀM