Báo cáo khoa học: "Mucin pattern reflects the origin of the adenocarcinoma in Barrett''''''''s esophagus: a retrospective clinical and laboratorial study" ppsx

Tài liệu Báo cáo khoa học: Multifunctional host defense peptides: Antimicrobial peptides, the small yet big players in innate and adaptive immunity docx

... MINIREVIEW Multifunctional host defense peptides: Antimicrobial peptides, the small yet big players in innate and adaptive immunity Constance Auvynet1,2,* and Yvonne Rosenstein11 Instituto de Biotecnologia, ... [13]. Cathelicidins killGram-positive and Gram-negative bacteria and Trypanosoma cruzi. Similar to defensins, cathelicidinsparticipate actively in linking innate and adaptive immunity and in modulating ... as in epithelial cellmigration, further suggesting a function for hBD2 in healing and protection of the intestinal epithelialbarrier [70].Proinﬂammatory and anti -in ammatory signalsof antimicrobial...

Tài liệu Báo cáo khoa học: An engineered disulﬁde bridge mimics the effect of calcium to protect neutral protease against local unfolding docx

... FEBS An engineered disulﬁde bridge mimics the effect of calcium to protect neutral protease against local unfolding Peter Duărrschmidt*, Johanna Mansfeld and Renate Ulbrich-HofmannDepartment of ... Model of the 3D structure of the neutral protease from Bacillus stearothermo-philus, including the position of the disulﬁde bridge in mutant G8C ⁄ N60C. The modelwas created on the basis of the ... act as an indicator for the occurrence of the intermediate in the unfolding. Calcium ions are the main contributory factor to enzyme stability The binding of calcium ions seems to be the mainsource...

Tài liệu Báo cáo khoa học: Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat docx

... Tat cell penetrating peptide uptake (Eur. J. Biochem. 269) 501 Different mechanisms for cellular internalization of the HIV-1 Tat- derived cell penetrating peptide and recombinant proteins fused ... internalization of the full-length Tat protein construct and the Tat CPPDifferences in the mechanisms of internalization between the Tat peptide a nd the Tat fused p rotein was a lsoestablished by adding the ... translocation of the full-length Tat protein and cellular uptake o f its basicdomain make u se of the s ame mechanism. B oth g enetic and biological evidence indicates that the cellular uptake of the Tat...

Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx

... meaning. It is the in interaction of the results of these asynchronous processes that the process of comprehension is defined. The processes are independent of the know- ledge representations ... activation of all meanings of each recognized word in HOPE, the determination of the phonetic representation of a recognized word determines the breadth of active competition amon 9 meanings ... time depending on the input, interconnections to other information, and an automatic activity decay scheme. In addition, the decay scheme is based on the state of the information, whether it...

Báo cáo khoa học: Leishmania donovani methionine adenosyltransferase Role of cysteine residues in the recombinant enzyme pptx

... [16].Ó FEBS 2003 Cysteine residues in leishmanial MAT (Eur. J. Biochem. 270)31 Leishmania donovani methionine adenosyltransferase Role of cysteine residues in the recombinant enzyme Yolanda Pe´rez-Pertejo1, ... domain of eachsubunit, in the interface between the two dimers compri-sing the tetrameric structure [29]. This domain containsﬁve cysteine residues, two of them (Cys35 and Cys61)forming a ... min. The role of the seven cysteine residues in L. donovani MAT was studied using the site-directed mutagenesisapproach, in which seven single mutants were produced,each lacking one of the sulfhydryl...

Báo cáo khoa học: "GRAMMATICAL AN ALYSIS BY COMPUTER OF THE LANCASTER OSLO/BERGEN (LOB) CORPUS OF BRITISH ENGLISH TEXTS." potx

... ANALYSIS BY COMPUT~ OF THE LANCASTER- OSLO/BERGEN (LOB) CORPUS OF BRITISH ~NGLISH TEXTS. Andrew David Beale Unit for Computer Research on the English Language Bowland College, University of ... potential tag B divided by the frequency of A. Subsequently, it was changed to the frequency of A followed by B divided by the product of the frequency of A and the frequency of B (Marshall, 1983: ... complexity of ordinary sentences in the corpus, and partly to create a databank of manually parsed samples of the LOB corpus, for the purposes of providing a first- approximation of the statistical...

Báo cáo khoa học: Broad antibiotic resistance proﬁle of the subclass B3 metallo-b-lactamase GOB-1, a di-zinc enzyme potx

... reverse:(5Â-GATCTTGCTGCTTACTGCGGCTCACTACGACCATACAGG-3Â)(5Â-GCACCTGTATGGTCGTAGTGAGCCGCAGTAAGCAGC-3Â)For the Q116N mutant forward and reverse:(5Â-GATCTTGCTGCTTACTAACGCTCACTACGACCATACAGG-3Â)(5Â-GCACCTGTATGGTCGTAGTGAGCGTTAGTAAGCAGC-3Â)For ... reverse:(5Â-GATCTTGCTGCTTACTAACGCTCACTACGACCATACAGG-3Â)(5Â-GCACCTGTATGGTCGTAGTGAGCGTTAGTAAGCAGC-3Â)For the Q116H mutant forward and reverse:(5Â-GATCTTGCTGCTTACTCATGCTCACTACGACCATACAGG-3Â)(5Â-GCACCTGTATGGTCGTAGTGAGCATGAGTAAGCAGC-3Â)Production and ... to the mass of the last three amino acids of the signal peptide, LNA. Another of the unidentiﬁedpeptides, of mass 1282, is the mass of the N-terminalpeptide less 17 Da, suggesting that the...

Báo cáo khoa học: cAMP increases mitochondrial cholesterol transport through the induction of arachidonic acid release inside this organelle in Leydig cells pdf

... Journal compilation ª 2006 FEBS cAMP increases mitochondrial cholesterol transport through the induction of arachidonic acid release inside this organelle in Leydig cells Ana Fernanda Castillo, ... mitochondria. The absence of hormone ⁄ cAMP- induced steroidsynthesis when protein synthesis is inhibited can beexplained now by the inhibition in the induction of ACS4 [28] during the early response ... feature in the regu-lation of cholesterol transport by arachidonic acid and the release of arachidonic acid in specialized compartment of the cells could offer novelmeans for understanding the regulation...

Báo cáo khóa học: Nerve growth factor mediates activation of the Smad pathway in PC12 cells doc

... represents the limiting component of TGF-b1 signaling in PC12 cells. Smad2 phosphorylationwasanalysedinparentalPC12cellsandinstablePC1 2cells expressing TbRII-wt under the control of a doxycycline-inducible ... stimulation of PC12 cells results in activation of the Smad pathway independently of TGF-b1. This activation is direct andresults in nuclear translocation of Smad3 within only30 min of NGF treatment. ... Coexpression of Smad3 and Smad4 , however, enhances the Smad3 effect. In Fig. 3. Mode of Smad activation by NGF. (A) Induction of speciﬁcR-Smads was investigated using the p3TP-luc(+) reporter. PC12 cells were...

Báo cáo khoa học: "Redundancy Ratio: An Invariant Property of the Consonant Inventories of the World’s Languages" pdf

... span amuch larger range for the vowel inventories than for the consonant inventories. The signiﬁcance of the difference in the nature of the distribution of RRs for the vowel and the conso-nant ... measure of redun-dancy is almost an invariance over the consonant inventories of the world’s languages. The observa-tion is important since it can shed enough light on the organization of the consonant ... LinguisticsRedundancy Ratio: An Invariant Property of the Consonant Inventories of the World’s LanguagesAnimesh Mukherjee, Monojit Choudhury, Anupam Basu, Niloy GangulyDepartment of Computer Science and Engineering,Indian...

Báo cáo khoa học: Complement factor 5a receptor chimeras reveal the importance of lipid-facing residues in transport competence doc

... suggestingthat the lipid-facing residues within a single TM segment are not essentialfor oligomerization. These studies highlight the importance of the lipid-facing residues in the complement factor ... dense packing of TM1 with the other helices,causing a slight shift of TM1 relative to the rest of the bundle (Fig. 3A). At the same time, the main kinks in the TM helices of rhodopsin (e.g. the functionallyimportant ... inter-action of the calcitonin -receptor- like receptor and the receptor- activity modifying proteins to dictate the ligand speciﬁcity of the receptor [14].Another possibility is that the lipid-facing residues may...

Báo cáo khoa học: Cupiennin 1a, an antimicrobial peptide from the venom of the neotropical wandering spider Cupiennius salei, also inhibits the formation of nitric oxide by neuronal nitric oxide synthase pptx

... 2007 FEBS Cupiennin 1a, an antimicrobial peptide from the venom of the neotropical wandering spider Cupiennius salei, also inhibits the formation of nitric oxide by neuronal nitric oxide synthase Tara ... inhibit the formation of NO by neuronal nitric oxide synthase (nNOS) [10]. Theseparticular amphibian peptides (e.g. the caerins 1 andsplendipherin [11]), are basic and hinged, and inhibit the operation ... synthase at an IC50concentration of 1.3 ± 0.3 lm. This is the ﬁrst report of neuronal nitric oxide synthase inhi-bition by a component of a spider venom. The mechanism by which cupi-ennin 1a inhibits...

Báo cáo khoa học: "Last but Definitely not Least: On the Role of the Last Sentence in Automatic Polarity-Classification" pdf

... 2010.c2010 Association for Computational Linguistics Last but Definitely not Least: On the Role of the Last Sentence in Automatic Polarity-Classification Israela Becker and Vered Aharonson AFEKA – ... experiment we examined the readers’ rating of the same re-views based on reading single sentences ex-tracted from these reviews: the last sentence or the second one. The second sentence could ... for last sentence only (b), and for second sentence only (c). 334 of paragraphs they were asked to read by rely-ing on sentences in initial positions. These find-ing subsequently gained...

Báo cáo hóa học: " Research Article Simple Statistical Analysis of the Impact of Some Nonidealities in Downstream VDSL with Linear Precoding" doc

... ProcessingVolume 2010, Article ID 454871, 14 pagesdoi:10.1155/2010/454871 Research Article Simple Statistical Analysis of the Impact of Some Nonidealities in Downstream VDSL with Linear PrecodingMarco ... obtained to express their impact. A simple approach is presentedfor computing the maximum line length where linear precoding overcomes the noncoordinate system. Then, the eﬀect of out -of- domain ... Signal Processingline whereas dnis the length of the considered in- domaindisturbed line.To evaluate the impact of the out -of- domain crosstalk,we introduce the following two parameters:Tn1=CnI−CnVACnI·100,Tn2=CnVA−CnNACnVA·100,(36)where,...

Báo cáo khoa học: "Mucin pattern reflects the origin of the adenocarcinoma in Barrett''''s esophagus: a retrospective clinical and laboratorial study" ppsx

... same pattern already described for incom-plete intestinal metaplasia of the stomach, and is furtherevidence that BE and incomplete intestinal metaplasia of the stomach are the same condition and ... adenocarcinoma arising in Barrett's esophagus (BE)may indicate the carcinogenesis pathway. The aim of this study was to evaluate resected specimens of adenocarcinoma in BE for the pattern of ... the pathologists and involved in laboratory investi-gation. AVSR was involved in collecting data, laboratoryinvestigation, carried out the immunoassays. All authorsread and approved the final...

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