Báo cáo khoa học: "Granulosa cell tumor of the ovary and antecedent of adjuvant tamoxifen use for breast cancer" pot

... random appearance and tamoxifen use does not appear to increase the risk of granulosa cell tumor of the ovary. ConsentWritten informed consent was obtained from the patient for publication of this ... Granulosa cell tumor of the ovary and antecedent of adjuvant tamoxifen use for breast cancer. WorldJournal of Surgical Oncology 2010 8:67.Submit your next manuscript to BioMed Central and take ... receive tamoxifen therapy and only two previous cases has beenreported in literature till date. It’s probable that the association of granulosa cell tumor and the use of tamoxifen for breast...

Báo cáo khoa học: "Malignant mixed tumor in the salivary gland of a cat" potx

... caudal base of the right ear. The mass was surgically removed and histopathologically confirmed as a malignant mixed tumor, suggesting local recurrence of the primary tumor. The radiotherapy was ... medicine, there are three types of malignant mixed tumors of the salivary glands, carcinoma ex mixed tumors, carcinosarcomas, and metastatic mixed tumors with a benign appearance [3]. Nearly 99% of ... fluctuated and painless subcutaneous swelling was palpated and found to contain a firm mass in the right mandibular region. In addition, the left mandibular lymph node was enlarged and the right mandibular...

báo cáo khoa học: "Topoisomerase II alpha gene copy loss has adverse prognostic significance in ERBB2-amplified breast cancer: a retrospective study of paraffin-embedded tumor specimens and medical charts" ppsx

... different chemotherapeutic agents.With the recent approval of Trastuzumab for the adjuvant treatment of BC and expanding its use, the importance of exploring molecular markers in the vicinity of ERBB2 ... BT and RR gathered and interpreted clinical data. LM and KJperformed the FISH analysis and interpreted the data. AZ and SB performed statistical analysis and helped to format and interpret the ... Isolated tumor cells in the bone marrow (ITC-BM) of breast cancer patients before and after anthracyclin based therapy: influenced by the HER2- and Topoisomerase IIalpha-status of the primary tumor? ...

Tài liệu Báo cáo khoa học: An alternative isomerohydrolase in the retinal Muller cells of a cone-dominant species doc

... from the area of the 11cROL and 13cROL peaks and expressed as the mean ± SD of three independent measurements.Retinal cell dissociation The zebraﬁsh eyes were enucleated, and the corneas and ... afterincubation of the atRE-liposomes with 125 lg of total cell lysate expressing RPE65c. The time courses of 11cROL and 13cROL production appeared linear in the initial phase (Fig. 5A). Therefore, all of ... software for evolutionaryanalysis of DNA and protein sequences. Brief Bioinform9, 299–306.53 Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of...

Tài liệu Báo cáo khoa học: Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae docx

... space, and the proteolysis must therefore represent a loss of 2 kDafrom the N-terminus. Given there are seven arginine and lysine residues spread through the N-terminalstretch of Om14, the three ... structuredwithin the plane of the membrane. Initial proteomics on the outer mem-brane from yeast mitochondria suggest that while most of the proteincomponents are integral in the membrane, most of these ... the membrane and most of the integral outer membrane proteins behave as if theyhave a-helical transmembrane segments, partitioninginto the detergent phase after Triton X-114 extraction of the...

Tài liệu Báo cáo khoa học: "Finding Synonyms Using Automatic Word Alignment and Measures of Distributional Similarity" pdf

... in the vector of the target word under consideration. The alignment frequencies are used for weighting the features and for applying the frequency cutoff.In the following section we describe the ... applied and the results of the synonymextraction task.5.1.1 Data and ResourcesAs our data we used the Dutch CLEF QA cor-pus, which consists of 78 million words of Dutch2Note that we use the ... a well-known combinatorialmeasure that computes the ratio between the size of the intersection of two feature sets and the sum of the sizes of the individual feature sets. Dice†is a measure...

Báo cáo khoa học: Staphylococcus aureus elongation factor G – structure and analysis of a target for fusidic acid pdf

... Comparison of the positions of the tip of domain IV inall available EF-G structures in the PDB. The structures were superimposed on the basis of domains I and II. Looking from the direction of the ... new conformation is signiﬁ-cant, as it demonstrates the size of the conforma-tional space of EF-G when not bound to the ribosome. The active conformation of EF-G is the one thatoccurs on the ... is the connection to domain IV. (C) Mutation sites in helices AV and BVat the surface of domain V. Gly621 and Gly617 are in the area of contact with the 1095 and 2473 regions of 23S RNA. The...

Báo cáo khoa học: Protein transport in organelles: The Toc complex way of preprotein import pdf

... in the expression of the corre-sponding genes [17,65]. Therefore, the extent of the physical involvement of the two receptors, atToc33 and atToc159, in the translocation of the photosyn-thetic ... indicate the presence of multiple cop-ies of at least some of the components and that the Toc core complex is oligoheteromeric. A stoichiometry of the puriﬁed pea Toc core complex of 1 : 4–5 : 4 for Toc159 ... together with the Toc75 channel, form the core of the Toc com-plex. The two GTPases act as GTP-dependent receptors at the chloroplastsurface and promote insertion of the preprotein across the Toc75...

Báo cáo khoa học: Glutamic acid residues in the C-terminal extension of small heat shock protein 25 are critical for structural and functional integrity pptx

... shown), and is a predominant residue in the ﬂexible regions of both human and murine sHsps. The majority of residues present in the ﬂexible regions of the extensions (71% and 74% for human and mur-ine, ... onto the column. The peak positions of the elution of molecular standards are indicated at the top of the graph. The elution of wild-type Hsp25 corresponds to an averagemolecular mass of 613 ... extension. Because of the proximity between the E190 residue of Hsp25 and the Fig. 7. Chaperone activity of wild-type and mutant Hsp25, as measured by the suppression of precipitation of insulin...

Báo cáo khoa học: Relation between domain evolution, speciﬁcity, and taxonomy of the a-amylase family members containing a C-terminal starch-binding domain pot

... separate evolution of this domain [30].This together with the ﬁndings of the present study indicatesa separate evolution of the domains C and E compared to the domains A and B. The recent introduction ... performed using the programCLUSTAL W[90] and then manually tuned whererequired. The method used for building the evolutionarytrees was the neighbour-joining method [91] with the Phylip format ... in the SBDtree. For comparison, the values of sequence identity for the SBD from B. circulans strain 251 CGTase with the SBDsfrom the CGTases from Thermococcus sp. B1001, Bacillusohbensis,andThermoanaerobacter...

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