... Schroen
1*
Abstract
Background: Lumpectomy re-excision to obtain negative margins is common. We compare the effect of two
specimen orientation approaches on lumpectomy re-excision rates.
Methods: All women undergoing lumpectomy ... Singh et al.: The effect of intraoperative specimen
inking on lumpectomy re-excision rates. World Journal of Surgical
Oncology...
... recogni-
tion, the ionic strength of the medium would be
expected to have an effect on the binding [43]. To
study the effect of ionic strength on the conformation
of ToxRp in the presence of ZnO NP, CD ... Titration
experiments consisted of 25 successive injections of ToxRp
protein (injection volume 10 lL; concentration 160 lm) into
the reaction cell (1.4 mL) containing Zn...
... supporting
the possibility of an autocrine mechanism for the suppres-
sion of colony formation (Fig. 5).
Finally, we confirmed the inhibitory effect of the ST2
protein on colony formation in soft agar by adding
exogenous ... were
carried out in conventional culture conditions. In these
studies, we could not draw any significant conclusions about
the effect of ST2 expression on c...
... day of chemotherapy
Xia et al. Radiation Oncology 2011, 6:50
http://www.ro-journal.com/content/6/1/50
Page 8 of 9
RESEARCH Open Access
The effect of bioequivalent radiation dose on
survival of ... Jeremic B: Effects of prolongation of overall treatment
time due to unplanned interruptions during radiotherapy of different
tumor sites and practical methods for compensation. Int...
... radio-adaptive response can be measured in terms of
cell survival – as performed in our study -, of reduction of
chromosomal aberrations, of micronuclei formation or of
mutations [3,22-24]. It ... experi-
mental conditions [12,13].
Most radio-adaptive response experiments focussed on
basic research of this phenomenon, with only few studies
concentrating on its clinical applica...
... Arg-HCl
in the absence of the chaperone precluded analysis of
the effect of this concentration on the protective
ability of aB-crystallin.
Reduction-induced aggregation of the insulin B-chain
Light ... incubated alone (Fig. 2A,C). Addition of Arg-HCl
(up to 250 mm) had a negligible effect on the amount
of precipitation. Similarly, low and intermediate con-
centrations o...
... addition
of 100 lLof2· Kirby buffer [25] and 80 lLofH
2
O, and
rRNA was obtained by precipitation after two phenol–
chloroform extractions. Four micrograms of rRNA were
treatedwith20lL of acetic-aniline ... effect of substitutions
made at each of the arginyl residues on catalytic activity of
RTA, the ability of each of the purified RTA variants to
depurinate yeast ribosomes...
... attentional
salience. One determiner of whether attentional
or propositional effects are dominant is the type of
information provided by the accented constituent.
Because nonpronominals contribute ... may be nonlexical
representations of concepts, or some hybrid of lexical,
conceptual and sensory data.
is preferred over a sequence of retentions, which is
preferred over a seq...
... interactions (Fig. 4D).
Effect of the M100K mutation on the stability
of the native state
The effect on protein stability upon introduction of a
Lys ligand to the heme-iron has been assessed for the
M100K ... amounts
of guanidinium hydrochloride (GdmHCl) the protein
unfolds resulting in the perturbation of a number of
electronic absorption bands and the appearance in the
s...
... counteracting long-range electrostatic
interactions that would otherwise act as destabilizing
forces for native-like conformations.
Conclusions
The comparison of apo- and holo-lMb by MD simu-
lations reveals ... be
taken as a model of an unstable intermediate in holo-
lMb unfolding on loss of the cofactor. The MD simu-
lation results provide an explanation of why such a
conformation...