... Open Access
The role of 18F-FDG-PET/CT in the preoperative
staging and posttherapy follow up of
gastriccancer: Comparison with spiral CT
Elgin Ozkan, Mine Araz
*
, Cigdem Soydal and Ozlem N Kucuk
Abstract
Background: ... limitation th at the number of patients is
small especially in the first group, the number of studies
intheliteratureinvestigating...
... kinetically in uential
ionizations were identified in plots of k
lim
⁄ K
d
of pK
a
values 7.1 and 9.3,
again with the maximum value realized in the alkaline region. The poten-
tial origin of these kinetically ... substrate carbinolamine intermediate;
III, iminoquinone intermediate; IV, product Schiff base intermediate;
V, aminoquinol intermediate. In the oxidative half...
... compromised by the inhibition of
PI3K signaling with LY294002 in a fully supplemented
medium and within the tested time period (Fig. 3B, D).
QDs induce the formation of LDs in PC12 cells
in a growth ... possibility; however, the inhibition
of PI3K with LY294002 and the inhibition of FAS
with cerulenin caused the disappearance of droplets
and prevented...
... cm
)1
correlates with a broad
band around 1400 cm
)1
at 25 °C of about the same
integral intensity, indicating a larger population of lin-
ear conformers. The upshift and increase in intensity
of the peak ... SRE
fos
and SRE
Gfos
,
on the one hand, and SRE
GGfos
, on the other hand,
consists in the distinct strains acting on the helix ply of
these oligonucleo...
... less than the eight man-months spent
developing and testing the LSP definition grammar.
Tagging and head finding were performed on
a sample of 2157 noun definition texts, covering the
nouns ... working on improving the head
finder, as well as developing similar "grammars" for
posmominal phrases and for the major phrase
str~tures of other definition types....
... described for the
sulfuration of the C-terminal glycine in ThiS and
MoaD, involved in thiamine biosynthesis and molyb-
dopterin biosynthesis, respectively, and for the sulfura-
tion of uridine in tRNA ... methylases
[9]. How the sulfur is transferred into the carboxamide
group of glycine in the peptide chain remains to be
shown.
Neither the functions of th...
... escaping to the cytoplasm.
In order to gain insight into the interaction of the
stator arginine with the binding site, we modeled a
stretch of seven amino acids of helix 4 of subunit a
into the ... atoms of the c-ring, with the intention that only
the residues of the a subunit and the side chains of the
c-ring should be free to move during minimizat...
... this
treatment. The high degree of protection by ADP sug-
gests that the mitochondrial injury is caused by open-
ing of the mPTP. There is evidence that ADP inhibits
opening of the mPTP by occupying binding ... to the induction
of oxidative stress during ischemia ⁄ reperfusion in
brain.
There is a growing body of information concerning
the mechanism of ROS generation...
... mutagenesis of the involve-
ment of some of these residues in the docking and catalysis
of cinnamic acid. The impact of the active site mutations on
the binding and metabolism of cinnamic acid ... affect the binding of cinna-
mate and the coupling of the hydroxylation reaction [9].
This effect was probably due to a direct interaction of its
side-chain...
... the end of the simulation, despite having a close prox-
imity between Tyr hydroxyl groups (e.g. 2–3 A
˚
) and
the substrate in the initial model.
In addition to reducing the flexibility of the ... pep-
tides, often at the same cleavage site. Rather, the evi-
dence in this paper supports a role for the conserved
Gly residues (599, 603, 604, 611) in the loop,...