báo cáo khoa học: "Prognostic factors in patients with node-negative gastric cancer: an Indian experience" pdf

... 6RESEARCH Open AccessPrognostic factors in patients with node-negative gastric cancer: an Indian experienceRamakrishnan A Seshadri1*, Sunil B Jayanand1and Rama Ranganathan2AbstractBackground: ... gastric cancer, we wished to study the factors influencing thesurvival in Indian patients with node-negative gastric cancer, most of whom have advanced gastric cancer.This will help in the o ... Although the incidenceof gastric cancer in Indi a is less than other Asian coun-tries like Japan, Korea and China, the age-standardized(world) incidence of gastric cancer in Chennai (12.2 and6.0/100,000...

Báo cáo khoa học: "Prognostic factors in primary adenocarcinoma of the small intestine: 13-year single institution experience" ppt

... of any cur-ative surgical approach in patients with adenocarcinomaof the small bowel. The first step in improving the prog-nosis is to have an aggressive diagnostic approach in patients with ... purposes) with the tumor site, size, and existence of ulceration. Thecommon presenting signs and symptoms in our serieswere nausea, vomiting, abdominal pain, melena, weightloss, anemia, and a ... Uppergastrointestinal tract series with small intestinal followthrough is one of the most useful diagnostic tests. It yields an accurate diagnosis in 50 to 70% of patients with theneoplasm of small intestine...

Báo cáo khoa học: "Palliative radiotherapy in patients with a symptomatic pelvic mass of metastatic colorectal cancer" pot

... marginallysignificant factor (p = 0.0644) on univariate analysis in all cases. (b) In patients with pain, higher BED and CCRT was associated with improvedoutcome with statistical significance. (c) In patients ... presenting symptoms were pain(68 cases), bleeding (18 cases), and obstruction (nine cases). The pelvic mass originated from rectal cancer in 58 patients (73%) and from colon cancer in 22 patients ... Initially 72 patients (90%) were treated with surgery,including 64 complete local excisions; 77% in colon cancer and 81% in rectal cancer. The total RT dose ranged 8-60 Gy (median: 36 Gy) with...

Báo cáo khoa học: " Oral Pirfenidone in patients with chronic fibrosis resulting from radiotherapy: a pilot study" ppsx

... muscle testing and administeredquestionnaires as per the protocol. Cervical range ofmotion, using an inclinometer, was measured in 4 planesof motion including flexion, extension, right and left ... several animalmodels as well as human in vitro studies to alter cytokinesignaling and reduce or eliminate pulmonary inflamma-tion and fibrosis. Pirfenidone is currently being evaluated in phase ... radiotherapy[27]. Many studies of pentoxifylline include the additionof Vitamin E analogues, but studies investigating the com-bination treatment have also had varying degrees of suc-cess [12]. An animal...

Báo cáo y học: "Foot kinematics in patients with two patterns of pathological plantar hyperkeratosi" pdf

... (MTD), and Toe Off (TO). In addition, the range of motion (ROM)ateachjointand in each plane of motion was derived durin g HC to FF,FFtoAN,ANtoHO,HOtoMADandHOtoTO.Finally, the timing of FF, AN, ... 1988, 68:678-682.21. Freeman AC: A study of inter-observer and intra-observer reliability in the measurement of resting calcaneal stance position, and neutralcalcaneal stance position. Bri J Pod ... classi-fied using side (i.e. differences between left and rightlimb), to determine if any variances in these data weredue to interaction or covariance of these factors; ANOVA was computed with ‘Two-Factor...

Báo cáo khoa học: " JC virus in the pathogenesis of colorectal cancer, an etiological agent or another component in a multistep process?" pdf

... resulting in silentor abortive infection, or probably in cell transformationand cancer [28]. Despite these evidences, the role ofJCV in human malignancies, and of its oncoproteins in promoting ... sporadic in theirorigin and associated to different risk factors, such as adiet rich in fat and animal protein intake [13].JCV infection in human populationThe extent of the exposure to JCV infection ... instability in cells containingJCV [48]. JCV also by a hit and run mechanism, that isa transient effect, is able to trigg er genetic instability byinteracting with p53 and b-catenin in colonic...

Báo cáo khoa học: "Prognostic factors for lymph node metastasis from advanced squamous cell carcinoma of the skin of the trunk and extremities" doc

... signif-icant.ResultsWe included 57 patients in this study. They were 34 menand 23 women; mean age was 61.9 years (range 30–91years). 48 were Caucasians and 48 came from urban areas.Preceding chronic skin lesions ... issue.BackgroundSquamous cell carcinoma of the skin (SCCS) is one of themost common cancers around the word [1,2], with an increasing incidence at a rapid rate among Caucasians in Europe, America and Australia ... was T3 in 36 cases and T4 in 21 cases.11 patients initially presented with lymph node metasta-sis (N1).Surgery was performed in 46 patients; exclusive radiationtherapy in 11. Eight patients...

Báo cáo khoa học: " Audiological findings in patients treated with radio- and concomitant chemotherapy for head and neck tumors" potx

... audiological findings in 15 patients with head and neck tumors, treated with radio- and concomitant chemotherapy, using the samecriteria to define ototoxicity. Their results showed that85% of patients ... importance of making the audi-tory evaluation, pre and post-treatment, in all patients submitted to conventional radiotherapy treatment com-bined with chemotherapy with cisplatin for head andneck ... study of inner ear radiation dose and hearingloss in head-and-neck cancer patients. Int J Radiat Oncol Biol Phys2005, 61:1393-1402.12. Blakley BW, Gupta AK, Myres SF, Schwan S: Risk factors...

Báo cáo khoa học: Protein transport in organelles: The Toc complex way of preprotein import pdf

... asso-ciated with the Toc complex and contains three TPR motifsforming the docking site for Hsp90-bound preproteins. AtToc12 (12)exposes a J-domain (J) into the intermembrane space and has arole in anchoring ... sequence spans the intermembrane spaceand is cleaved by an envelope bound type-I signal pep-tidase. A polyglycine stretch in the C-terminal partappears to play an essential role in retaining Toc75 ... A. thaliana Toc proteinsinvolved in preprotein translocation across the outer membrane ofchloroplasts. The Toc core complex is formed by the two GTP-bind-ing proteins atToc159 (159) and atToc33...

Báo cáo khoa học: Functional symmetry in the isolated domain demonstrated by N-ethylmaleimide labelling pdf

... chain to the nucleotide-binding pocket [3].We describe the engineering, expression and puriﬁcation ofsingle-cysteine-containing proteins comprising either theC-terminal NBD or the N-terminal ... NBDs interact in a similar manner with 2-deoxy-ATP and CTP. Lastly, the data provide evidencethat ITP and dTTP bind weakly, and that their respectiveinteraction with the N-terminal and C-terminal ... 75-kDafusion protein containing a single cysteine residue located in the ATP-binding pocket. The production of a similar fusionprotein containing the C-terminal NDB of P-glycoprotein ishampered...

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