báo cáo khoa học: "Gastrointestinal Stromal Tumours treated before and after the advent of c-kit immunostaining" pptx
báo cáo khoa học: "Gastrointestinal Stromal Tumours treated before and after the advent of c-kit immunostaining" pptx
... AccessGastrointestinal Stromal Tumours treated before and after the advent of c-kit immunostainingPaolo G Sorelli1*, Patrizia Cohen2, Bafour Amo-Takyi2, Nikitas A Theodorou1 and Peter M Dawson1AbstractBackground: ... allGISTs are characterised by the expression of the c-kit receptor (CD117), as is their cell of origin, the intersti-tial cell of Cajal [2]. Detection of the c-kit protein intumour cells by ... Mesenchymal tumours of the gastrointestinal tract: a paradisefor acronyms (GUMP, GIST, GANT, and now GIPACT). Implications of c-kit in genesis, and yet another of many emerging roles of the interstitialcell...
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Tài liệu Báo cáo khoa học: Long-distance interactions between enhancers and promoters The case of the Abd-B domain of the Drosophila bithorax complex pdf
... However, when the combination of the PTS and the bound-ary is placed 3¢ to one of the reporter genes, the enhancer istargeted to one or the other promoter over the boundary (lowerpanel). E1 and E2: ... later than in the case of the histone gene cluster [10]. This difference in the tim-ing of somatic pairing perhaps reflects the differencebetween the complexities of the regulation of the twosystems: ... locate and physically approach theirproper target promoter in the viscous environment of the nucleus.Somatic pairing of chromosomes and the regulation of Abd-BA peculiarity of Drosophila is the...
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Báo cáo khoa học: " Loratadine dysregulates cell cycle progression and enhances the effect of radiation in human tumor cell lines" pot
... dividing the density of the released DNA band by the density of the total DNA in the l ane (the released DNAband plus the unreleased DNA remaining in the well).Cell Cycle Analysis The effect of loratadine ... increase in the percen-tage of cells in the G2/M phase of the cell cycle. Since the G2/M phase of the cell cycle is one of the most sen-sitive to radiation [17], this could explain some of the increased ... Both ends of the tubing were clamped, and the tubing was immersed inan ice bath to rapidly solidify the agarose. The agarosewas then extruded f rom the tubing, cut into 5 mmlengths, and the se...
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báo cáo khoa học: "Gastrointestinal stromal tumors: correlation between symptoms at presentation, tumor location and prognostic factors in 47 consecutive patients" pot
... Sant’Andrea Hospital, Faculty of Medicine and PsychologyUniversity of Rome “La Sapienza, Italy.3Department of Pathology,Sant’Andrea Hospital, Faculty of Medicine and Psychology University of Rome ... all deaths occur-ring in the gastric group were related to other diseases, and none of them were related to the disease progression.Figure 3b shows the comparison of the overall survivalcurves ... Italy.4Department of Oncology, Sant’Andrea Hospital,Faculty of Medicine and Psychology University of Rome “La Sapienza”, Italy.Authors’ contributionsSC, MC and VZ designed the study; NP, LL, EP, AR and...
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Báo cáo khoa học: "Gastrointestinal stromal tumor" potx
... changed GIST therapy. This drug inhibits the KIT and PDGFR tyrosine kinases as well as other mem-bers of the type III group of tyrosine kinases [68,69]. How-ever, after the introduction of molecular ... occupa-tion. The most common location of GIST is stomach (50-60%) and small intestine (30%-40%). Five to ten percent of GISTs arise from the colon and rectum, and 5% arelocated in the esophagus. Other ... paragangliomatouspattern [12]. Diagnosis of GIST is often delayed, due to the vague nature of symptoms, for even 6 months after the onset of the symptoms. [10]. Although, the diagnosticprocedure includes...
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Báo cáo khoa học: "Gastrointestinal stromal tumor of the stomach with lymph node metastasis" ppsx
... editing of the manuscript, ON wrote the pathologicalpart of the manuscript and OS performed the IHC and contributed the IHC part of the manuscript and photom-icrographs. All authors read and approved ... contributed fordecision of the adjuvant treatment planning. The postop-erative course of the patient was uneventful.Reported recurrence rates of 17–21% and 5-year survivalrates of 48–70% even in ... rate, C-KIT and PDGFRAgenotype are the major determinants of malignant poten-tial of the tumor which have significant impact on prog-nosis [20-22]. A practical grading system for GIST after surgical...
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Báo cáo khoa học: "Gastrointestinal stromal tumour and hypoglycemia in a Fjord pony: Case report" pps
... cytoplasm and oval nuclei. Many of thesecells seemed to be adherent to each other. The blood ves-sels penetrated the muscular layers of the stomach and entered the tumour. This mass consisted of densely ... kg. The tumour was enclosed within the omentum majus, located between the liver and stomach cranially and the colon caudally, and attached by a relatively small stalk to the pyloric part of the ... 37 kg and was enclosed within the greater omentum, locatedbetween the liver and stomach cranially and the coloncaudally, and attached by a relatively small stalk to the pyloric part of the stomach....
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Tài liệu Báo cáo khoa học: Erythrochelin – a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea docx
... characterization of these compounds isgrowing and may result in the synthesis of specificinhibitors based on the structure of the pathogensiderophore [16].A promising approach for the isolation of secondarymetabolites, ... to the identification of the second siderophore(data not shown). We therefore assume that either the extraction conditions were inadequate for the iso-lation of the natural product, or that the ... in the etc gene cluster. The N-terminal C-domain of the NRPS catalyzes the a-N-acetylation of haOrn1in cis.Cyclorelease of the assembled tetrapeptide mediated by the C-terminal C-domain of...
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Tài liệu Báo cáo khóa học: Determination by electrospray mass spectrometry and 1H-NMR spectroscopy of primary structures of variously fucosylated neutral oligosaccharides based on the iso-lacto-N-octaose core doc
... Leadeterminant.As the C3aion is at m/z 690, this excludes the possibility of the other Fuc being at the Gal next to the subterminalGlcNAc. The position of the second Fuc 3-linked to the internal ... 6-branch, and believed to befrom a contaminant (see below), having the same molecularmass with one Fuc in each of the 3- and 6-branches.Comparison of the product-ion spectra of the singly and doubly ... downfield from the Fuc IX H5 proton. ForTFiLNO, the same temperature would have resulted in totaloverlap of the H2O signal with the Fuc X and XI H5protons. Therefore the temperature of 27 °C was...
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Tài liệu Báo cáo khoa học: An immunomodulator used to protect young in the pouch of the Tammar wallaby, Macropus eugenii pptx
... (i.e. when the young has no immune system of its own), whenthere is a profound fall in the microbial flora of the pouch [6]. Neither eugenin nor other low molecularmass components of the pouch ... asstimulation of the proliferation of lymphocytes, activa-tion of CCK receptors stimulate production of inter-leukins and secretion of immunoglobulins on the mucosal surface of the intestine [49,50]. The ... Eugenin corresponds to the caeruleins in having the same first four residues, but the sequence after the Tyr(SO3) residue of eugenin is different from those of the other mammalian and amphibian analogues...
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