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Báo cáo y học: "The use and abuse of commercial kits used to detect autoantibodies" ppsx

Báo cáo y học:

Báo cáo y học: "The use and abuse of commercial kits used to detect autoantibodies" ppsx

... high level of security, of scrutiny and of standardization, and under good labora-tory practices and quality control. Many of these compa-nies subscribe to and offer postmarketing qualityassurance ... chain of production, use and application of autoantibody test kits. 198PatientThe ongoing demands of quality control and quality assur-ance are highly dependent on the availability of prototypesera ... specificity), reliability, and quality of many commercial kits. In many cases the manu-facturer has been assumed the root cause for these short-comings; however, the use of commercial kits and theirappropriate...
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Báo cáo y học: "Alcohol use and abuse in training conscripts of the Hellenic navy" pps

... differentfrom those used in older age groups [13]. It is very impor-tant for the Hellenic Navy to have a profile of alcohol use and abuse of the training conscripts, firstly because theNavy is responsible ... of alcohol use and abuse were measured in a sample of 650male training conscripts of the Hellenic Navy. The tools used are: (a) two questionnaires measuringfrequency and quantity of alcohol ... frequency and quantity of alcohol use, along with psy-chosocial complications related to alcohol use. Problematic alcohol use is considered to be a predictor forfuture alcohol abuse and/ or addiction...
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Báo cáo Y học: The processivity and fidelity of DNA synthesis exhibited by the reverse transcriptase of bovine leukemia virus pot

Báo cáo Y học: The processivity and fidelity of DNA synthesis exhibited by the reverse transcriptase of bovine leukemia virus pot

... activity of RT specifically hydrolysesthe RNA in these heteroduplexes. Finally, the plus-senseDNA strand is synthesized by copying of the minus-senseDNA strand by the DNA-dependent DNA polymerase(DDDP) ... processivity and fidelity of DNA synthesis exhibitedby the reverse transcriptase of bovine leukemia virusOrna Avidan, Michal Entin Meer, Iris Oz and Amnon HiziDepartment of Cell Biology and Histology, ... Virology 259, 176–189].In the p resent study, we have studied in vitro two features of the DNA polymerase activity of BLV RT, t he processivity of DNA synthesis and the fidelity of DNA synthesis....
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Báo cáo y học:

Báo cáo y học: "The identification and characterization of a novel protein, c19orf10, in the synovium" docx

... Canada2Department of Physics and Astronomy, University of Manitoba, 510 Allen Building, Winnipeg, Manitoba, R3T 2N2, Canada3Section of Rheumatology, Department of Internal Medicine, Faculty of Medicine, ... fusion protein and the reac-tivity and specificity of the purified IgY were confirmed usingGST-c19orf10 and a panel of unrelated His and GST fusionproteins. The antibody was then used to establish ... properly cited.AbstractJoint inflammation and destruction have been linked to thederegulation of the highly synthetic fibroblast-like synoviocytes(FLSs), and much of our current understanding of...
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Báo cáo y học: "The promise and reality of personal genomics" pot

... likely to be easy to both genotype and sequence. The sensitivity of SNP and indel detection in repetitive or copy-number-variable regions will be lower. Finally, a non-trivial proportion of any ... missed is likely to be substantially higher, however, as the set of ‘true’ calls used to derive the SNP sensitivity estimates (from the Illumina 610K genotyping array) is biased towards regions ... (Solexa) [4] and Applied Biosystem’s SOLiD [5] systems - but no explicit comparison of the two versions has yet been published.MinireviewThe promise and reality of personal genomicsBryndis Yngvadottir,...
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Báo cáo y học: " The yin and yang of chromatin spatial organization" ppt

... article and many more, are likely be important in dynamically shaping the spatial environment and organization of the genome.Specialized transcriptionfactoryTranscription factoryRegulatory proteinNuclear ... factory simultaneously. is may stabilize their presence at the shared factory through factor sharing, in other words the increased local concentration of specific regulatory factors may increase ... JA, Horton A, Wood AL, Bolland DJ, Corcoran AE, Fraser P: Myc dynamically and preferentially relocates to a transcription factory occupied by IgH. PLoS Biol 2007, 5:e192.18. Lin C, Yang L,...
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Báo cáo y học: "The promise and limitations of population exomics for human evolution studies" doc

... strategy used to generate an exome dataset differs slightly between population genetics and phenotype association studies. In association analyses, the goal is usually to maximize the number of ... population size to detecting positive selective sweeps, and they may be missed by other methods. However, phenotypically causal noncoding variants and truly neutral regions far from genes and free ... targets of selection, such as the regulatory region of the lactase gene LCT, may leave little detectable signature in exomes [13].Finally, exomes present the difficulty of a deluge of data. Storing...
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Báo cáo y học: "The contact-mediated response of peripheral-blood monocytes to preactivated T cells is suppressed by serum factors in rheumatoid arthritis" ppt

... initially been implied in thepathogenesis of the disease because of the association of related HLA DRB1 alleles with susceptibility to and severity of the disease, and have subsequently been found to ... also used as stimulators and found to be potentinducers of cytokine production in monocytic THP-1 cells [27],in monocytes from healthy donors [10,28] and in mononuclearcells isolated from synovial ... preserved the inhibitory activity,whereas increasing the temperature to 70 or 95°C resulted ina loss of that inhibitory activity. Thus, the inhibitory activity isdue to heat-labile factors.Direct...
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Báo cáo y học: "The use of 3D surface scanning for the measurement and assessment of the human foot" doc

... that arecustomised to the individual. Suggestions are made for future areas of research and for the standardization of theprotocols used to produce foot scans.BackgroundThe use of 3D surface ... approaches and ana-tomical landmarks are used to define foot length. Typi-callyitistakenasbeingfromthepterniontothetipofthe second toe but on the Brannock device it is definedby using an ... can be used to inform the design of the orthotic, and while this can currently be achieved using kinematicanalysis of motion capture data from gait labs, themajority of podiatrists and other...
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Báo cáo y học: " The use of partial exchange blood transfusion and anaesthesia in the management of sickle cell disease in a perioperative setting: two case reports" pot

... anartery catheter can be used to analyze blood gas and monitor the haemoglobin level during the surgicalprocedure.Because patients with SCD generally have a history of chronic pain and thus a history ... cases of longer procedures withincreased fluid shifts, a urinary catheter i s indicated to monitor urinary volume. Hypoxemia due to hypoventila-tion must be avoided by way of adequate monitoringthroughout ... mmol/litre, and the hematocrit was 0.36.On the day of the surgery, the boy received 3 mg of Midazolam intravenously. The oxygen saturation wasmonitored using pulse oximetry. His body temperaturewas...
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