... cofactor for
L. donovani interaction with ECM and BM. Both Zn
2+
and
free sulfhydryls may be required for LBP binding site on
laminin a s e videnced by the stimulatory and inhibitory
effects of ... protein
of
Leishmania
is stimulated by zinc and may involve laminin
zinc-finger like sequences
Keya Bandyopadhyay, Sudipan Karmakar, Abhijit Ghosh and Pijush K. Das
Molecular Cell Bi...
... activation of the corresponding phosphatases.
Lastly, our data reveal a multiplicity of effects of cell
stresses on translation regulators, and their profound
inhibitory effect on protein synthesis. ... consequences of toxic effects leading
to a loss of cell viability.
In view of this substantial inhibition of protein
synthesis, it will be important to consider their...
... form, affinity chroma-
tography was then used to purify PAK68. The autophos-
phorylation and kinase activity of PAK were stimulated by
binding to activated Rac/Cdc42, which thereby directly
modulates ... antibodies, and poly-
clonal antibodies to PAK65 and to PAK62 were obtained
from Santa Cruz Biotech, Inc. Polyclonal antibodies to
human gp91phox and Rac1 were kindly provi...
...
level of prior to surgery, 1 day after surgery, and 3
days after surgery, the amount of transfusion during
surgery, estimated blood loss during operation, pla-
cental accreta, hysterectomy, myomectomy, ... parity,
history of cesarean section and history of abortion
should be adjusted when demographic investigation
on placenta previa is pursued [1].
In our study, in additi...
... inflam-
mation, fatty liver and IMT to explore as to which of
these factors are related to IMT.
Subjects and Methods
Subjects
A total of 86 obese Chinese children were
enrolled from July 2008 to March ...
intra-assay and inter-assay coefficient of variations
were less than 2.1% and 4.4%, respectively. Plasma
levels of IL-6 and TNF were measured by en-
zyme-l...
... assessment of the severity of the liver
disease. During each follow-up, signs and symptoms of
possible adverse effects should be evaluated. If treatment
is continued in the presence of adverse effects, ... weighed by the severity of
disease, the predicted success rate, the anticipated adverse
effects and the cost and availability of the drugs. The
decision t...
... treatment [16].
4. Indications of HBV Treatment
Historically, levels of HBV DNA and ALT, and histological activity of liver biopsy have been used as the three main factors to
determine if a patient ... On-treatment Monitoring and Duration of Therapy
Patients who receive HBV treatment should be monitored regularly. The interval of follow-up visits may vary depending on
r...
... [5–16]. How-
ever, very few cases of human obesity are reported to
be caused by genetic factors [17], leaving western-type
diet and sedentary lifestyle, physical inactivity and
imbalance in caloric ... in the
delivery of nonhydrolyzed dietary lipids to adipose
tissue. Taken together, our data establish that ApoE is
a key mediator of diet-induced obesity in response to
western-...
... interesting to analyze the binding specificity of the
different types of importin a toNLD-INLSandtothe
putative NLD-I type NLSs present in other nuclear
proteins.
ACKNOWLEDGEMENTS
We wish to thank ... 265–306.
14. Miyamoto, Y. , Imamoto, N., Sekimoto, T., Tachibana, T., Seki,
T., Tada, S., Enomoto, T. & Yoneda, Y. (1997) Differential modes
of nuclear localization signal (NLS) re...
... metric.
Another way to determine if an update is required is by
monitoring the nearby topology and disseminating update
packets only when a minimum level of topology change oc-
curs. To do this, ... periodically maintains the nearby topology by employ-
ing a proactive routing strategy (such as distance vector or
link state) and maintain approximate routes or on-demand
routes for...