Báo cáo y học: "The role of cyclooxygenase-2 in bone repair" doc

Báo cáo Y học: The role of zinc in the methylation of the coenzyme M thiol group in methanol:coenzyme M methyltransferase from Methanosarcina barkeri New insights from X-ray absorption spectroscopy doc

Báo cáo Y học: The role of zinc in the methylation of the coenzyme M thiol group in methanol:coenzyme M methyltransferase from Methanosarcina barkeri New insights from X-ray absorption spectroscopy doc

... & Penner-Hahn, J.E. (1998) Characterization of the zinc binding site in methionine synthase enzymes of Escherichia coli – the role of zinc in the methylation of homocysteine. J. Am. Chem Soc. 120, 8410–8416. 15. ... to ligation of the thiol group of coenzyme M. Mutations in His237 or Cys239, which are proposed to be involved in ligating zinc, resulted in an over 90...
Ngày tải lên : 17/03/2014, 23:20
  • 7
  • 464
  • 0
Báo cáo y học: "The role of Probiotics in allergic diseases" pptx

Báo cáo y học: "The role of Probiotics in allergic diseases" pptx

... allergy. factors influencing development of the microbiota. Ann Med 1999, 31(4):288-92. 15. Kalliomaki M, Isolauri E: Role of intestinal flora in the develop- ment of allergy. Curr Opin Allergy Clin ... The role of the intestinal microflora for the development of the immune system in early childhood. Eur J Nutr 2002, 41(Suppi 1):I32-7. 18. Penders J, et al.: Molecular finger...
Ngày tải lên : 08/08/2014, 21:20
  • 7
  • 560
  • 0
Báo cáo y học: "The role of osteoprotegerin in arthritis" ppsx

Báo cáo y học: "The role of osteoprotegerin in arthritis" ppsx

... consequently lead to increasing inter- est in the role of osteoclasts in local bone erosion that is driven by the hypothesis that synovial pannus makes use Review The role of osteoprotegerin in arthritis Georg ... the spreading of inflammatory synovial tissue [8]. Evidence for a pivotal role of osteoclasts in local bone erosions Bone erosion requires osteoclasts an...
Ngày tải lên : 09/08/2014, 01:23
  • 7
  • 343
  • 0
Báo cáo y học: "The role of leptin in innate and adaptive immune responses" doc

Báo cáo y học: "The role of leptin in innate and adaptive immune responses" doc

... an inflammatory challenge by altering production of proinflammatory and anti-inflammatory cytokines and may also affect cytokine signaling by a variety of mechanisms, including induction of SOCS-3 ... whereas in processes involving innate immunity, anti-inflammatory effects of leptin are prevalent. However, it is difficult to elucidate the role, if any, of leptin during inflammat...
Ngày tải lên : 09/08/2014, 08:22
  • 10
  • 469
  • 0
Báo cáo khoa học: The role of DYRK1A in neurodegenerative diseases docx

Báo cáo khoa học: The role of DYRK1A in neurodegenerative diseases docx

... of DYRK1A detected by immuno- cytochemistry (Fig. 1) indicate that the role of DYRK1A in development, maturation, aging and degeneration may vary in different brain structures and with the types ... observed in rat [16] and mouse [17] brains. The difference in phosphorylation of DYRK1A in cell compartments indicates that intra- cellular trafficking of DYRK1A may be regulate...
Ngày tải lên : 22/03/2014, 16:21
  • 10
  • 446
  • 0
Báo cáo Y học: The role of the second binding loop of the cysteine protease inhibitor, cystatin A (stefin A), in stabilizing complexes with target proteases is exerted predominantly by Leu73 pdf

Báo cáo Y học: The role of the second binding loop of the cysteine protease inhibitor, cystatin A (stefin A), in stabilizing complexes with target proteases is exerted predominantly by Leu73 pdf

... glycosylated proteins of about 50–90 kDa. The single polypeptide chain of a kininogen contains three domains resembling family 2 cystatins. Cystatins competitively inhibit the activity of papain- like ... second binding loops of cystatin B and family 2 cystatins and also what residues of this loop in cystatin A may participate in the interaction. To elucidate the role of the...
Ngày tải lên : 17/03/2014, 10:20
  • 10
  • 533
  • 0
Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf

Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf

... Tyr. These mutations may in uence the shape and volume of the acyl binding pocket and thereby alter the binding mode and affinity of the enzyme for PAA and derivatives thereof, while maintaining the ... phenylglycyl- and p-hydroxyphe- nylglycyl-enzyme of bF24A, as indicated by, respectively, a twofold and fourfold increased V s /V h ratiocomparedtothe wild-type (Table 4). The V s /V h r...
Ngày tải lên : 17/03/2014, 23:20
  • 8
  • 561
  • 0
Báo cáo Y học: The role of arginine residues in substrate binding and catalysis by deacetoxycephalosporin C synthase potx

Báo cáo Y học: The role of arginine residues in substrate binding and catalysis by deacetoxycephalosporin C synthase potx

... carboxyl group of the a-aminoadipoyl- side-chain of penicillin N (1), with arginines 74 and 75 apparently playing a less important role in side-chain binding. Taken together, the results of this ... ternary com- plex to oxygen binding, thereby initiating catalysis and ensuring coupling of 2-oxoglutarate conversion to prime substrate oxidation. In the case of DAOCS it has been...
Ngày tải lên : 18/03/2014, 01:20
  • 5
  • 462
  • 0
Báo cáo y học: "The role of cyclooxygenase-2 in bone repair" doc

Báo cáo y học: "The role of cyclooxygenase-2 in bone repair" doc

... their role in bone metabolism and repair remains unclear. Review of the evidence To determine the role of COX-2 in bone repair, investiga- tors have studied fracture healing in animal models of COX-2 ... 17:963-976. 11. Einhorn TA. Do inhibitors of cyclooxygenase-2 impair bone healing? J Bone Miner Res 2002, 17:977-978. 12. Zhang X, Schwarz EM, Young DA, Puzas JE,...
Ngày tải lên : 09/08/2014, 01:21
  • 3
  • 475
  • 0
Báo cáo y học: "The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis" ppt

Báo cáo y học: "The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis" ppt

... occurs at the β-carbon of the asparagine residue, consequently (by way of steric hindrance) preventing the interaction of the HIF-α C-TAD with the cysteine/histidine-rich 1 domain of p300, a co-activator ... variation in the relative expression of the PHD isoforms in different cells, with PHD-2 being the most abundant HIF prolyl hydroxylase. Specific ‘silencing’ of all three e...
Ngày tải lên : 09/08/2014, 01:22
  • 9
  • 499
  • 0

Xem thêm

Từ khóa: