... ch ELISA wasperformed as described previously [6,9,10]. Each samplewas assayed in duplicate and intra-assay coefficients ofvariation sample values were always <15%. Clinicalinvestigatorswereunawareofthelaboratoryresultsuntil ... study. MRY, MM, helpedto acquired, analyzed and interpreted the clinical data and made criticalrevision of the manuscript. All authors read and approved the finalmanuscript.Competing interestsThe ... AD, JC have conceived and designed the research; analyzed and interpreted the data; performed statistical analysis, handled funding and supervision and drafted the manuscript. RRG, DB, OM, have...