... substrates, including vincristine, requireGSH for their transport and that vincristine inhibits the high affinity DNP-SG transport in the presence but not in the absence of GSH [12,45,46]. Thus the effect ... Unoninh; 1 ¼ ni¼ 2 ð3Þwhere I is the concentration of the inhibitor, IC50is the inhibitor concentration producing 50% inhibition of the inhibitable component, U0is the uptake in the absence ... 1A). Uptake of [3H]cGMP in the absence of ATP but in the presence of the nonhydrolysableATP analogue, ATP-c-S, was less than 5% of the uptake in the presence of ATP. The amount of [3H]cGMP...