... (SBs) are important intermediates for the synthesis of some bioactive compounds such as ß-lactams [16–18], and employed as ligands for the complexation of metal ions [19]. SBs and their complexes ... HNNNHNHNSNH2NHHNNOThiosemicarbazideScheme 29. Pandeya SN, Sriram D, Nath G, De Clercq E (1999) Synthesis antibacterial antifungal and anti-HIV activities of Schiff and Mannich bases derived from isatin derivatives and N-[4-(4'-chlorophenyl)thiazol-2-yl]thiosemicarbazide. ... (1964) The quantitative analysis of drugs, vol 3. Chapman and Hall Ltd., Tokyo, pp 456–458 28. Duh PD, Tu YY, Yen GC (1999) Antioxidant activity of water extract of Harng Jyur (Chyrsanthemum...