... histone H3, biotinyl-ated at K4, K9 and K18. DiscussionThis study provides evidence (a) that K4, K9 and K18 in histone H3 are good targets for biotinylation by human biotinidase; (b) that K14 and ... ofbiotinylated lysines in histone H3: N1)9(including K4 and K9) , N9)16(including K9 and K14), N16)23(inclu-ding K18 and K23), and N18)25(including K18 and K23); subscripts denote the amino acid ... K23 are relativelypoor targets for biotinylation; (c) that human cellscontain histone H3, biotinylated in positions K4, K9 and K18; and (d) that dimethylation of arginine resi-dues in histone...