... a- chain, tropomyosin b-chain, myosin regulatory light chain 2, myosin light chain 3, and parvalbumin -a. Analyses of mRNA have revealed that PPARa suppressed the genes encodingthese proteins in a ... is a target for thisinhibitor. The basal activation of the Jak/STAT pathwayinvolved in IL-2R signal transduction in CALO and INBL cellssuggest that this pathway may play a role in the pathogenesis ... throughincreased binding of the Ternary Complex Factor (TCF), such asElk-1, to the SRE and transcriptional activation, and activation of a histone kinase, such as the MAPK-activated protein kinase(MAPKAP-K)...