Báo cáo khoa học: " Synergistic effect of ERK inhibition on tetrandrine-induced apoptosis in A549 human lung carcinoma cells" docx
Báo cáo khoa học: " Synergistic effect of ERK inhibition on tetrandrine-induced apoptosis in A549 human lung carcinoma cells" docx
... Synergistic effect of ERK inhibition on tetrandrine-induced apoptosis in A549 human lung carcinoma cells 27Fig. 7. The effects of a PI3K/Akt inhibitor and an MEK /ERK inhibitor on tetrandrine ... carcinogen modulates the phenotype of normal human airway epithelial cells. J Clin Invest 2003, 111, 81-90. Synergistic effect of ERK inhibition on tetrandrine-induced apoptosis in A549 human lung ... resulted in a decrease in Akt and ERK expression. PI3K inhibition had no clear synergistic effect on tetradrine-induced apoptosis, however, ERK inhibition resulted in a significant synergistic effect...
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Tài liệu Báo cáo khoa học: "The Effect of Pitch Accenting on Pronoun Referent Resolution" ppt
... sequence of shifts. When intonation and centering collide My synthesis of the claims in PH90 and GJW89 pro- duces an attentional interpretation of pitch accents, modeled by operations on Cf, ... corresponding propositional effect as described in PH90. The corollaries for pitch accented pronominals are: (1) when a pitch accent is applied to a pronominal, its main effect is attentional, on ... interpreted for what they say about attentional salience. One determiner of whether attentional or propositional effects are dominant is the type of information provided by the accented constituent....
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Báo cáo khoa học: The effect of HAMP domains on class IIIb adenylyl cyclases from Mycobacterium tuberculosis pptx
... MCP, suggest an interaction of a HAMP domain with a flavin adenine dinucleotide-bindingPAS-domain (acronym for period clock protein, arylhydrocarbon receptor, single-minded protein) [13]. Further,it ... to contain 16–25 mMMn2+ in the cytosol [18]demonstrating that some bacteria indeed accumulateMn2+to high concentrations.An interesting question concerns the role of the HAMP-region and ... may result in rather individual structure-function relationships includingcrosstalk between HAMP-domains and their adjoiningeffector modules [11].Correspondence to J. U. Linder, Abteilung Pharmazeutische...
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Báo cáo khoa học: "Prophylactic effect of plaster and cataplasm contained ketoprofen in rats with adjuvant arthritis" pot
... bone mineral density in ovariecto-mized rat. Calcif. Tissue. Int. 1993, 52, 442-446.18. Thompson, D. D. and Rodan, G. A. Indomethacin inhibi-tion of tenotomy-induced bone resorption in rats. ... 138137LA)suspended in 0.1 ml of paraffin oil.Measurements of foot sizeFoot volumes of the injected (right hindpaw) and non-injected (left hindpaw) paws were measured up to a markmade on the tibiotarsal joint ... 7 after the adjuvant injection. After day 7, the CTseemed to be the more effective in the non-injected paw.Fig. 1. Changes of paw edema by injection of adjuvant in the control (●), plaster-...
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Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx
... 100Counts020406080100Counts020406080100Counts100101102103104100101102103104100101102103104100101102103104100101102103104100101102103104None+saponin+saponin– saponin+saponin– saponinRabbit IgsNone+saponinRabbit IgsABCDCD1d upregulation in iron-loaded HepG2 cells M. Cabrita et al.154 ... ferritin expression in nonpermeabilized (thin lines,– saponin) and permeabilized cells (thick lines, + saponin) cells cul-tured without and with iron as indicated. (D) Perls’ staining of cyto-spins ... further increase in ROS production as deter-mined by an increase in DCFH mean fluorescenceintensity (Fig. 2B, thick line). In addition, determin-ation of acrolein adducts, a marker of oxidative...
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báo cáo hóa học: " The effect of pharmacological treatment on gait biomechanics in peripheral arterial disease patients" pptx
... decrease in range of motion of thehip during stance as it was found in our study. This is log-ical when considering the entire kinetic chain. Whenmotion at one joint is decreased, another joint in ... and the increased range of motion during stance, are affected by changes that occurfurther up in the kinetic chain at the hip joint. Theincrease in the range of motion of the ankle during stancewas ... values are in degrees of motion. AROM - Ankle range of motion; KROM - Knee range of motion; HROM - Hip range of motion.Huisinga et al. Journal of NeuroEngineering and Rehabilitation 2010, 7:25http://www.jneuroengrehab.com/content/7/1/25Page...
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báo cáo hóa học:" The effect of oxygen tension on calcium homeostasis in bovine articular chondrocytes" pptx
... perturbation of normal Ca2+ levelsFigure 3 Effect of hypoxia and antimycin A on mitochondrial membrane pd of bovine articular chondrocytes. Chondrocytes were isolated as in Figure 1, being maintained ... antimycin A) all resulted in decreasedCa2+. Hypoxia also induced depolarization of mitochon-dria, indicative of a reduction in electron flow throughthe mitochondrial electron transport chain, ... Wilkins RJ: Rapid effects of hypoxia on H+ homeostasis in articular chondrocytes. Pflug Archiv 2009, 458:1085-1092.61. Browning JA, Wilkins RJ: The effect of intracellular alkalinisation on...
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Báo cáo hóa học: " The Effect of Interface Texture on Exchange Biasing in Ni80Fe20/Ir20Mn80 Syste" potx
... A˚under conditions (a)–(c), Hextends to saturate.The last phenomenon is consistent with X-ray and X-TEMresults indicating that the continuation of the (111)Fig. 1 The hysteresis loop of a glass/Ta(30 ... xincreases beyond 90 A˚. Hcis inversely proportional to x,which is caused by the spin coupling or decoupling effect near the NiFe/IrMn interface.Experiment DetailsThe top-configuration ... / Published online: 25 November 2008Ó to the authors 2008Abstract Exchange-biasing phenomenon can induce anevident unidirectional hysteresis loop shift by spin cou-pling effect in the ferromagnetic...
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Tài liệu Báo cáo khoa học: The effect of small molecules in modulating the chaperone activity of aB-crystallin against ordered and disordered protein aggregation pdf
... precipitation in the presence of high concentrations of Arg-HCl in the absence of the chaperone precluded analysis of the effect of this concentration on the protectiveability of aB-crystallin.Reduction-induced ... specifically increase theactivity of aB-crystallin against DTT-induced precipi-tation of insulin at intermediate and high concentra-tions, and it also increased the activity of aB-crystallin in preventing ... analysis of the purified proteins indicated thatthey contained < 5% contaminating proteins. The concen-trations of proteins used in these studies were determinedby spectrophotometric methods using...
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Tài liệu Báo cáo khóa học: The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain pptx
... challenged withincreasing concentrations of toxin at 37 °C for 4 h. Remaining proteinsynthesis after this time was measured by the incorporation of (35S)methionine. Symbols indicate the mean of four ... challengedwith increasing concentrations of ricin (d),orricinN78S(j)at37°Cfor 4 h. Remaining protein synthesis after this time was measured bythe incorporation of (35S)methionine. Symbols indicate ... majority of the interactions thatwere seen in the first model are maintained. However, theinteraction between G4andAsn122cannolongerbemadeas G4is in an altered position making a continuous...
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